EC 2.3.1.9: acetyl-CoA C-acetyltransferase

TransferasesOpen in Browse

CatLog read 49 records for EC 2.3.1.9 from 7 papers, for 7 organisms. Names in these papers: 3-ketoacyl-CoA thiolase Tfu_0875, acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, 3-oxoacyl-CoA thiolase A (thiolase A), mitochondrial acetoacetyl-CoA thiolase (T2) and 4 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 45 records for EC 2.3.1.9 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.9 in Browse.

Papers

Papers with records for EC 2.3.1.9
Paper	Organisms	Records
Enhancing the activity and succinyl-CoA specificity of 3-ketoacyl-CoA thiolase Tfu_0875 through rational binding pocket engineering	Thermobifida fusca	16
Enterococcus faecalis acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, a dual-function protein of isopentenyl diphosphate biosynthesis	Enterococcus faecalis	13
Substrate specificities of 3-oxoacyl-CoA thiolase A and sterol carrier protein 2/3-oxoacyl-CoA thiolase purified from normal rat liver peroxisomes. Sterol carrier protein 2/3-oxoacyl-CoA thiolase is…	Rattus norvegicus	8
Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function	Homo sapiens	7
Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target	Aspergillus fumigatus	3
Effect of an oxygen-tolerant bifurcating butyryl coenzyme A dehydrogenase/electron-transferring flavoprotein complex from Clostridium difficile on butyrate production in Escherichia coli	Clostridium difficile	1
Conversion of 4-hydroxybutyrate to acetyl coenzyme A and its anapleurosis in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate carbon fixation pathway	Metallosphaera sedula	1

Records

Records for EC 2.3.1.9 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
3-ketoacyl-CoA thiolase Tfu_0875	Thermobifida fusca	acetyl-CoA	0.0035	2.28	0.0015	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875, acetyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875	Thermobifida fusca	glutaryl-CoA	0.0035	2.33	0.0015	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875, glutaryl-CoA
3-ketoacyl-CoA thiolase Tfu_0875	Thermobifida fusca	malonyl-CoA	0.0032	3.32	0.001	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875, malonyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875	Thermobifida fusca	succinyl-CoA	0.0053	2.1	0.0025	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875, succinyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W	Thermobifida fusca	acetyl-CoA	0.0052	1.15	0.0045	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W, acetyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W	Thermobifida fusca	glutaryl-CoA	0.0033	2.27	0.0015	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W, glutaryl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W	Thermobifida fusca	malonyl-CoA	0.0035	2.89	0.0012	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W, malonyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W	Thermobifida fusca	succinyl-CoA	0.0055	1.37	0.004	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W, succinyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W/L163H	Thermobifida fusca	acetyl-CoA	0.0037	2.19	0.0017	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W/L163H, acetyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W/L163H	Thermobifida fusca	glutaryl-CoA	0.0033	2.28	0.0015	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W/L163H, glutaryl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W/L163H	Thermobifida fusca	malonyl-CoA	0.0033	2.77	0.0012	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W/L163H, malonyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W/L163H	Thermobifida fusca	succinyl-CoA	0.0065	1.14	0.0057	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W/L163H, succinyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W/L163H/E217L	Thermobifida fusca	acetyl-CoA	0.0043	2.18	0.002	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W/L163H/E217L, acetyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W/L163H/E217L	Thermobifida fusca	glutaryl-CoA	0.005	2.2	0.0023	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W/L163H/E217L, glutaryl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W/L163H/E217L	Thermobifida fusca	malonyl-CoA	0.003	2.57	0.0012	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W/L163H/E217L, malonyl-CoA
3-ketoacyl-CoA thiolase Tfu_0875variant N249W/L163H/E217L	Thermobifida fusca	succinyl-CoA	0.0098	0.59	0.0167	pH 7.4, 37 °C	PMID 38694995	Open record: 3-ketoacyl-CoA thiolase Tfu_0875 variant N249W/L163H/E217L, succinyl-CoA
3-oxoacyl-CoA thiolase A (thiolase A)	Rattus norvegicus	3-Oxohexadecanedioyl-CoA	—	0.0034	—	pH 8, 25 °C	PMID 9325339	Open record: 3-oxoacyl-CoA thiolase A (thiolase A), 3-Oxohexadecanedioyl-CoA
3-oxoacyl-CoA thiolase A (thiolase A)	Rattus norvegicus	3-Oxooctanoyl-CoA	—	0.0091	—	pH 8, 25 °C	PMID 9325339	Open record: 3-oxoacyl-CoA thiolase A (thiolase A), 3-Oxooctanoyl-CoA
3-oxoacyl-CoA thiolase A (thiolase A)	Rattus norvegicus	3-Oxopalmitoyl-CoA	—	0.0078	—	pH 8, 25 °C	PMID 9325339	Open record: 3-oxoacyl-CoA thiolase A (thiolase A), 3-Oxopalmitoyl-CoA
3-oxoacyl-CoA thiolase A (thiolase A)	Rattus norvegicus	Acetoacetyl-CoA	—	0.0077	—	pH 8, 25 °C	PMID 9325339	Open record: 3-oxoacyl-CoA thiolase A (thiolase A), Acetoacetyl-CoA
3-oxoacyl-CoA thiolase A (thiolase A)	Rattus norvegicus	CoAAcetoacetyl-CoA fixed at 25 μM; cosubstrate Acetoacetyl-CoA	—	0.0078	—	pH 8, 25 °C	PMID 9325339	Open record: 3-oxoacyl-CoA thiolase A (thiolase A), CoA
3-oxoacyl-CoA thiolase A (thiolase A)	Rattus norvegicus	CoA3-Oxooctanoyl-CoA fixed at 10 μM	—	0.009	—	pH 8, 25 °C	PMID 9325339	Open record: 3-oxoacyl-CoA thiolase A (thiolase A), CoA
3-oxoacyl-CoA thiolase A (thiolase A)	Rattus norvegicus	CoA3-Oxopalmitoyl-CoA fixed at 10 μM	—	0.0045	—	pH 8, 25 °C	PMID 9325339	Open record: 3-oxoacyl-CoA thiolase A (thiolase A), CoA
3-oxoacyl-CoA thiolase A (thiolase A)	Rattus norvegicus	CoA3-Oxohexadecanedioyl-CoA fixed at 10 μM	—	0.0085	—	pH 8, 25 °C	PMID 9325339	Open record: 3-oxoacyl-CoA thiolase A (thiolase A), CoA
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), acetoacetyl-CoA thiolase activity	Enterococcus faecalis	acetoacetyl-coenzyme A	—	0.088	—	pH 9.5, 37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), acetoacetyl-CoA thiolase activity, acetoacetyl-coenzyme A
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), acetoacetyl-CoA thiolase activity	Enterococcus faecalis	acetyl-coenzyme A	—	0.6	—	pH 10.5, 37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), acetoacetyl-CoA thiolase activity, acetyl-coenzyme A
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), acetoacetyl-CoA thiolase activity	Enterococcus faecalis	coenzyme A	—	0.01	—	pH 9.5, 37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), acetoacetyl-CoA thiolase activity, coenzyme A
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	3-hydroxy-3-methylglutaryl-coenzyme A	—	0.02	—	pH 6.5, 37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, 3-hydroxy-3-methylglutaryl-coenzyme A
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	coenzyme Areaction 5; oxidative acylation of mevaldehyde to HMG-CoA	—	0.22	—	37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, coenzyme A
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	coenzyme Areaction 6; oxidative acylation of mevalonate to HMG-CoA	—	0.23	—	37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, coenzyme A
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	mevaldehyde	—	3.8	—	pH 7, 37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, mevaldehyde
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	mevaldehyde	—	0.66	—	37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, mevaldehyde
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	mevalonate	—	1	—	37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, mevalonate
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	NADP+reaction 5; oxidative acylation of mevaldehyde to HMG-CoA	—	0.67	—	37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, NADP+
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	NADP+reaction 6; oxidative acylation of mevalonate to HMG-CoA	—	0.25	—	37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, NADP+
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	NADPH	—	0.03	—	pH 6.5, 37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, NADPH
acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity	Enterococcus faecalis	NADPH	—	0.25	—	pH 7, 37 °C	PMID 11914342	Open record: acetoacetyl-CoA thiolase/HMG-CoA reductase (mvaE gene product), HMG-CoA reductase activity, NADPH
Acetoacetyl-CoA β-ketothiolase	Metallosphaera sedula	acetoacetyl-CoA	1 × 10³	0.18	5.6 × 10³	pH 7.5, 70 °C	PMID 24532060	Open record: Acetoacetyl-CoA β-ketothiolase, acetoacetyl-CoA
Acetyl-CoA C-acetyltransferase (thiolase, THIA1)	Clostridium difficile	Acetoacetyl-CoA	469	0.033	1.4 × 10⁴	pH 8	PMID 23772070	Open record: Acetyl-CoA C-acetyltransferase (thiolase, THIA1), Acetoacetyl-CoA
AfERG10A (mitochondrial acetyl-CoA acetyltransferase)	Aspergillus fumigatus	acetoacetyl-coenzyme A	3	0.043	70 calc.	pH 8.1, 30 °C	PMID 32005728	Open record: AfERG10A (mitochondrial acetyl-CoA acetyltransferase), acetoacetyl-coenzyme A
AfERG10A (mitochondrial acetyl-CoA acetyltransferase)	Aspergillus fumigatus	acetyl-coenzyme A	7	0.232	30 calc.	pH 7.4, 30 °C	PMID 32005728	Open record: AfERG10A (mitochondrial acetyl-CoA acetyltransferase), acetyl-coenzyme A
AfERG10A (mitochondrial acetyl-CoA acetyltransferase)	Aspergillus fumigatus	coenzyme A	5	0.026	190 calc.	pH 8.1, 30 °C	PMID 32005728	Open record: AfERG10A (mitochondrial acetyl-CoA acetyltransferase), coenzyme A
mitochondrial acetoacetyl-CoA thiolase (T2)	Homo sapiens	2-methylacetoacetyl-coenzyme A40 mM KCl	61	0.008	7.6 × 10³ calc.	pH 8.1, 25 °C	PMID 17371050	Open record: mitochondrial acetoacetyl-CoA thiolase (T2), 2-methylacetoacetyl-coenzyme A
mitochondrial acetoacetyl-CoA thiolase (T2)	Homo sapiens	2-methylacetoacetyl-coenzyme A40 mM NaCl	14	0.008	1.8 × 10³ calc.	pH 8.1, 25 °C	PMID 17371050	Open record: mitochondrial acetoacetyl-CoA thiolase (T2), 2-methylacetoacetyl-coenzyme A
mitochondrial acetoacetyl-CoA thiolase (T2)	Homo sapiens	acetoacetyl-coenzyme A40 mM KCl	21	0.004	5.2 × 10³ calc.	pH 8.1, 25 °C	PMID 17371050	Open record: mitochondrial acetoacetyl-CoA thiolase (T2), acetoacetyl-coenzyme A
mitochondrial acetoacetyl-CoA thiolase (T2)	Homo sapiens	acetoacetyl-coenzyme A40 mM NaCl	7.4	0.008	920 calc.	pH 8.1, 25 °C	PMID 17371050	Open record: mitochondrial acetoacetyl-CoA thiolase (T2), acetoacetyl-coenzyme A
mitochondrial acetoacetyl-CoA thiolase (T2)	Homo sapiens	acetyl-coenzyme A	3.5	0.508	6.9 calc.	pH 7.4, 30 °C	PMID 17371050	Open record: mitochondrial acetoacetyl-CoA thiolase (T2), acetyl-coenzyme A
mitochondrial acetoacetyl-CoA thiolase (T2)	Homo sapiens	coenzyme A40 mM KCl	18	0.02	900 calc.	pH 8.1, 25 °C	PMID 17371050	Open record: mitochondrial acetoacetyl-CoA thiolase (T2), coenzyme A
mitochondrial acetoacetyl-CoA thiolase (T2)	Homo sapiens	coenzyme A40 mM NaCl	7	0.066	110 calc.	pH 8.1, 25 °C	PMID 17371050	Open record: mitochondrial acetoacetyl-CoA thiolase (T2), coenzyme A