CatLogenzyme kinetics catalog

EC 2.3.3.10: hydroxymethylglutaryl-CoA synthase

TransferasesOpen in Browse

CatLog read 28 records for EC 2.3.3.10 from 2 papers, for 2 organisms. Names in these papers: HMG-CoA synthase (avian cytosolic, recombinant), 3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 71 records for EC 2.3.3.10 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.3.10 in Browse.

Papers

PaperOrganismsRecords
The influence of conserved aromatic residues in 3-hydroxy-3-methylglutaryl-CoA synthaseGallus gallus17
Brassica juncea 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase 1: expression and characterization of recombinant wild-type and mutant enzymesBrassica juncea11

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)Brassica junceaacetyl-CoA0.4150.0439.7 calc.pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant C212SBrassica junceaacetyl-CoA0.0680.0292.4 calc.pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant H188NBrassica junceaacetoacetyl-CoA—0.012—pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant H188NBrassica junceaacetyl-CoA0.0480.0550.88 calc.pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant H188N/S359ABrassica junceaacetoacetyl-CoA—0.0029—pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant H188N/S359ABrassica junceaacetyl-CoA3.780.1232 calc.pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant N115ABrassica junceaacetyl-CoA0.390.02714 calc.pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant R157ABrassica junceaacetyl-CoA0.0280.0520.54 calc.pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant S356ABrassica junceaacetyl-CoA0.2680.02610 calc.pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant S359ABrassica junceaacetyl-CoA3.5680.024150 calc.pH 7.5, 30 °CPMID 15233626Open
3-hydroxy-3-methylglutaryl-CoA synthase 1 (BjHMGS1)variant S89ABrassica junceaacetyl-CoA0.1270.0187.0 calc.pH 7.5, 30 °CPMID 15233626Open
HMG-CoA synthase (avian cytosolic, recombinant)variant F204LGallus gallusacetyl-CoA—0.26—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant F204LGallus gallusacetyl-CoA—0.022—PMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y130FGallus gallusacetyl-CoA—0.565—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y130FGallus gallusacetyl-CoA—0.028—PMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y130LGallus gallusacetoacetyl-CoA—0.0033—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y130LGallus gallusacetyl-CoA—0.992—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y130LGallus gallusacetyl-CoA—1.268—PMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y163LGallus gallusacetyl-CoA—0.2—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y163LGallus gallusacetyl-CoA—0.012—PMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y225LGallus gallusacetyl-CoA—0.125—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y225LGallus gallusacetyl-CoA—0.002—PMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y346LGallus gallusacetyl-CoA—0.604—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y346LGallus gallusacetyl-CoA—0.02—PMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y376FGallus gallusacetyl-CoA—0.307—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y376LGallus gallusacetoacetyl-CoA—0.0031—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y376LGallus gallusacetyl-CoA—0.604—pH 8.2, 30 °CPMID 12743118Open
HMG-CoA synthase (avian cytosolic, recombinant)variant Y376LGallus gallusacetyl-CoA—0.608—PMID 12743118Open