CatLogenzyme kinetics catalog

EC 2.4.1.122: N-acetylgalactosaminide beta-1,3-galactosyltransferase

TransferasesOpen in Browse

CatLog read 14 records for EC 2.4.1.122 from 1 paper, for 1 organism. Names in these papers: C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1), DmC1GalT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase C1GalT1).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 8 records for EC 2.4.1.122 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.1.122 in Browse.

Papers

PaperOrganismsRecords
Structural basis for the synthesis of the core 1 structure by C1GalT1Drosophila melanogaster14

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterAla-Pro-Asp-Ser(alpha-D-GalNAc)-Arg-Pro-NH20.03180.24620.13pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterAla-Pro-Asp-Thr(alpha-D-GalNAc)-Arg-Pro-NH2secreted from HEK293 cells0.05880.1950.3pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterAla-Pro-Asp-Thr(alpha-D-GalNAc)-Arg-Pro-NH2residues S73-Q388; mellitin signal; Endo-H treated0.07850.32260.243 calc.pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterPhe-Ala-Ala-Thr(alpha-D-GalNAc)-Gly-Pro-Phe-NH20.08270.110.75pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterPro-Ala-Ala-Thr(alpha-D-GalNAc)-Gly-Pro-Phe-NH20.0320.055140.57pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterPro-Ala-Ala-Thr(alpha-D-GalNAc)-Gly-Pro-Tyr-NH20.05650.050061.13pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterTyr-Ala-Ala-Thr(alpha-D-GalNAc)-Gly-Pro-Phe-NH20.0270.083020.33pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterTyr-Ala-Ala-Thr(alpha-D-GalNAc)-Gly-Pro-Tyr-NH20.060.078170.77pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterTyr-Ala-Asp-Thr(alpha-D-GalNAc)-Gly-Pro-Phe-NH20.06680.13960.479 calc.pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasterTyr-Ala-Glu-Thr(alpha-D-GalNAc)-Gly-Pro-Phe-NH20.0860.11880.72 calc.pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasteruridine diphosphate galactoseAPDT*RP fixed at 1 mM; cosubstrate APDT*RP (1000 µM)0.05230.088270.6pH 7.5, 37 °CPMID 35504880Open
C1GalT1 (core 1 beta1,3-galactosyltransferase, T-synthase; DmC1GalT1)Drosophila melanogasteruridine diphosphate galactoseP4 fixed at 250 µM; cosubstrate P4 (PAAT*GPY, 250 µM)0.0560.035331.58pH 7.5, 37 °CPMID 35504880Open
DmC1GalT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase C1GalT1)Drosophila melanogasterAla-Pro-Asp-Thr(alpha-GalNAc)-Arg-Pro-NH2 (MUC1 glycopeptide, GalNAc alpha-O-linked to Thr)0.0580.1950.30 calc.pH 7.5, 37 °CPMID 35504880Open
DmC1GalT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase C1GalT1)Drosophila melanogasteruridine diphosphate galactose—0.088—pH 7.5, 37 °CPMID 35504880Open