EC 2.4.99.23: lipopolysaccharide heptosyltransferase I
TransferasesOpen in Browse
CatLog read 25 records for EC 2.4.99.23 from 2 papers, for 1 organism. Names in these papers: heptosyltransferase I (HepI).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 4 records for EC 2.4.99.23 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.4.99.23 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between the Substrate and Positively Charged Residues | Escherichia coli | 17 |
| Lipopolysaccharide biosynthesis without the lipids: recognition promiscuity of Escherichia coli heptosyltransferase I | Escherichia coli | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| heptosyltransferase I (HepI) | Escherichia coli | fully deacylated Kdo2-LipidAno detergent (without Triton X-100) | 0.76 | 2.8 × 10⁻⁴ | 2.7 × 10³ | PMID 22059588 | Open record: heptosyltransferase I (HepI), fully deacylated Kdo2-LipidA | |
| heptosyltransferase I (HepI) | Escherichia coli | fully deacylated Kdo2-LipidAwith Triton X-100 | 1.05 | 5 × 10⁻⁴ | 2.1 × 10³ | PMID 22059588 | Open record: heptosyltransferase I (HepI), fully deacylated Kdo2-LipidA | |
| heptosyltransferase I (HepI) | Escherichia coli | Kdo-LipidA (Re-LipidA)no detergent (without Triton X-100) | 8 | 0.046 | 170 | PMID 22059588 | Open record: heptosyltransferase I (HepI), Kdo-LipidA (Re-LipidA) | |
| heptosyltransferase I (HepI) | Escherichia coli | Kdo-LipidA (Re-LipidA)with Triton X-100 | 5.5 | 0.016 | 340 | PMID 22059588 | Open record: heptosyltransferase I (HepI), Kdo-LipidA (Re-LipidA) | |
| heptosyltransferase I (HepI) | Escherichia coli | Kdo2-LipidAno detergent (without Triton X-100) | 6.6 | 0.029 | 220 | PMID 22059588 | Open record: heptosyltransferase I (HepI), Kdo2-LipidA | |
| heptosyltransferase I (HepI) | Escherichia coli | Kdo2-LipidAwith Triton X-100 | 4.7 | 0.009 | 520 | PMID 22059588 | Open record: heptosyltransferase I (HepI), Kdo2-LipidA | |
| heptosyltransferase I (HepI) | Escherichia coli | O-deacylated Kdo2-lipid A | 0.36 | 0.0029 | 124 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI), O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI) | Escherichia coli | O-deacylated Kdo2-LipidAno detergent (without Triton X-100) | 1.06 | 9 × 10⁻⁴ | 1.1 × 10³ | PMID 22059588 | Open record: heptosyltransferase I (HepI), O-deacylated Kdo2-LipidA | |
| heptosyltransferase I (HepI) | Escherichia coli | O-deacylated Kdo2-LipidAwith Triton X-100 | 1.47 | 4 × 10⁻⁴ | 3.7 × 10³ | PMID 22059588 | Open record: heptosyltransferase I (HepI), O-deacylated Kdo2-LipidA | |
| heptosyltransferase I (HepI)variant K192A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.14 | 0.014 | 11 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant K192A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant K64A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.33 | 0.008 | 41 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant K64A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant K64A/R63A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.25 | 0.04 | 7 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant K64A/R63A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant K64A/R63A/R60A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.2 | 0.02 | 10 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant K64A/R63A/R60A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant K64A/R63A/R61A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.21 | 0.037 | 6 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant K64A/R63A/R61A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant K64A/R63A/R61A/R60A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.28 | 0.056 | 5 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant K64A/R63A/R61A/R60A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant K98A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.21 | 0.016 | 13.1 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant K98A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R120A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.32 | 0.015 | 21 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R120A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R120A/K64A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.47 | 0.034 | 14 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R120A/K64A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R120A/R60A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.281 | 0.0014 | 200 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R120A/R60A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R120A/R61A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.26 | 0.0029 | 90 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R120A/R61A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R120A/R63A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.37 | 0.011 | 30 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R120A/R63A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R189A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.116 | 0.006 | 19 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R189A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R60A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.198 | 0.006 | 33 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R60A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R61A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.36 | 0.0025 | 140 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R61A, O-deacylated Kdo2-lipid A |
| heptosyltransferase I (HepI)variant R63A | Escherichia coli | O-deacylated Kdo2-lipid A | 0.41 | 0.01 | 41 | pH 7.5, 37 °C | PMID 32011131 | Open record: heptosyltransferase I (HepI) variant R63A, O-deacylated Kdo2-lipid A |