EC 2.5.1.19: 3-phosphoshikimate 1-carboxyvinyltransferase
TransferasesOpen in Browse
CatLog read 58 records for EC 2.5.1.19 from 4 papers, for 3 organisms. Names in these papers: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase), 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), EPSP synthase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 85 records for EC 2.5.1.19 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.5.1.19 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Catalytic residues and an electrostatic sandwich that promote enolpyruvyl shikimate 3-phosphate synthase (AroA) catalysis | Escherichia coli | 28 |
| Characterization of Streptococcus pneumoniae 5-enolpyruvylshikimate 3-phosphate synthase and its activation by univalent cations | Streptococcus pneumoniae | 16 |
| Structural basis of glyphosate resistance resulting from the double mutation Thr97 -> Ile and Pro101 -> Ser in 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli | Escherichia coli | 8 |
| doi:10.1016/j.procbio.2006.11.006 | Pseudomonas aeruginosa | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | 5-enolpyruvylshikimate 3-phosphate | 0.23 | 0.00195 | 120 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), 5-enolpyruvylshikimate 3-phosphate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | phosphate | 0.22 | 0.343 | 0.64 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), phosphate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | phosphoenolpyruvate[NH4+] 1 mM; [K+] 0 mM | 2.1 | 0.1 | 21 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), phosphoenolpyruvate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | phosphoenolpyruvate[NH4+] 10 mM; [K+] 0 mM | 2.8 | 0.091 | 31 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), phosphoenolpyruvate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | phosphoenolpyruvate[NH4+] 100 mM; [K+] 0 mM | 3 | 0.022 | 140 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), phosphoenolpyruvate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | phosphoenolpyruvate[NH4+] 1 mM; [K+] 100 mM | 12.8 | 0.023 | 560 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), phosphoenolpyruvate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | phosphoenolpyruvate[NH4+] 1 mM; [K+] 75 mM | 7.6 | 0.028 | 270 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), phosphoenolpyruvate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | phosphoenolpyruvate[NH4+] 1 mM; [K+] 50 mM | 6.5 | 0.047 | 140 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), phosphoenolpyruvate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | phosphoenolpyruvate[NH4+] 1 mM; [K+] 10 mM | 2 | 0.085 | 24 calc. | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), phosphoenolpyruvate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | shikimate 3-phosphate[NH4+] 1 mM; [K+] 0 mM | — | 0.145 | — | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), shikimate 3-phosphate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | shikimate 3-phosphate[NH4+] 10 mM; [K+] 0 mM | — | 0.118 | — | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), shikimate 3-phosphate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | shikimate 3-phosphate[NH4+] 100 mM; [K+] 0 mM | — | 0.031 | — | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), shikimate 3-phosphate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | shikimate 3-phosphate[NH4+] 1 mM; [K+] 100 mM | — | 0.109 | — | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), shikimate 3-phosphate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | shikimate 3-phosphate[NH4+] 1 mM; [K+] 75 mM | — | 0.06 | — | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), shikimate 3-phosphate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | shikimate 3-phosphate[NH4+] 1 mM; [K+] 50 mM | — | 0.029 | — | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), shikimate 3-phosphate |
| 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase) | Streptococcus pneumoniae | shikimate 3-phosphate[NH4+] 1 mM; [K+] 10 mM | — | 0.049 | — | pH 7, 25 °C | PMID 10601870 | Open record: 5-enolpyruvylshikimate 3-phosphate synthase (EPSP synthase), shikimate 3-phosphate |
| 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) | Escherichia coli | phosphoenolpyruvate | — | 0.045 | 930 | pH 7.5 | PMID 19211556 | Open record: 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), phosphoenolpyruvate |
| 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) | Escherichia coli | shikimate-3-phosphate | — | 0.048 | 910 | pH 7.5 | PMID 19211556 | Open record: 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), shikimate-3-phosphate |
| 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)variant P101S | Escherichia coli | phosphoenolpyruvate | — | 0.071 | 250 | pH 7.5 | PMID 19211556 | Open record: 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) variant P101S, phosphoenolpyruvate |
| 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)variant P101S | Escherichia coli | shikimate-3-phosphate | — | 0.071 | 240 | pH 7.5 | PMID 19211556 | Open record: 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) variant P101S, shikimate-3-phosphate |
| 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)variant T97I | Escherichia coli | phosphoenolpyruvate | — | 0.38 | 23 | pH 7.5 | PMID 19211556 | Open record: 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) variant T97I, phosphoenolpyruvate |
| 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)variant T97I | Escherichia coli | shikimate-3-phosphate | — | 0.077 | 120 | pH 7.5 | PMID 19211556 | Open record: 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) variant T97I, shikimate-3-phosphate |
| 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)variant T97I/P101S | Escherichia coli | phosphoenolpyruvate | — | 0.1 | 57 | pH 7.5 | PMID 19211556 | Open record: 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) variant T97I/P101S, phosphoenolpyruvate |
| 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)variant T97I/P101S | Escherichia coli | shikimate-3-phosphate | — | 0.071 | 74 | pH 7.5 | PMID 19211556 | Open record: 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) variant T97I/P101S, shikimate-3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) | Escherichia coli | phosphoenolpyruvate50 mM KCl | — | 0.04 | 800 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase), phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) | Escherichia coli | phosphoenolpyruvate100 mM KCl | — | 0.15 | 90 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase), phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) | Escherichia coli | phosphoenolpyruvate100 mM KCl | — | 0.16 | 86 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase), phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) | Escherichia coli | shikimate 3-phosphate50 mM KCl | 32 | 0.018 | 1.8 × 10³ | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase), shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) | Escherichia coli | shikimate 3-phosphate100 mM KCl | 13 | 0.11 | 150 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase), shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) | Escherichia coli | shikimate 3-phosphate100 mM KCl | 14 | 0.14 | 96 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase), shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant D313A | Escherichia coli | phosphoenolpyruvate | — | 0.28 | 0.004 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant D313A, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant D313A | Escherichia coli | shikimate 3-phosphate | 0.0012 | 0.21 | 0.006 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant D313A, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant D313C | Escherichia coli | phosphoenolpyruvate | — | 1.3 | 0.02 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant D313C, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant D313C | Escherichia coli | shikimate 3-phosphate | 0.026 | 0.4 | 0.068 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant D313C, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant D313L | Escherichia coli | phosphoenolpyruvate | — | 1.6 | 7 × 10⁻⁴ | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant D313L, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant D313L | Escherichia coli | shikimate 3-phosphate | 0.0011 | 0.7 | 0.0016 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant D313L, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant D313N | Escherichia coli | phosphoenolpyruvate | — | 0.19 | 0.01 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant D313N, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant D313N | Escherichia coli | shikimate 3-phosphate | 0.0018 | 0.2 | 0.009 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant D313N, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant E341A | Escherichia coli | phosphoenolpyruvate | — | 0.05 | 0.009 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant E341A, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant E341A | Escherichia coli | shikimate 3-phosphate | 4.2 × 10⁻⁴ | 0.1 | 0.005 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant E341A, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant E341C | Escherichia coli | phosphoenolpyruvate | — | 0.17 | 0.021 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant E341C, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant E341C | Escherichia coli | shikimate 3-phosphate | 0.0036 | 0.08 | 0.044 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant E341C, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant E341M | Escherichia coli | phosphoenolpyruvate | — | 1.9 | 9 × 10⁻⁴ | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant E341M, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant E341M | Escherichia coli | shikimate 3-phosphate | 0.0017 | 0.035 | 0.05 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant E341M, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant E341Q | Escherichia coli | phosphoenolpyruvate | — | 0.9 | 0.0013 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant E341Q, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant E341Q | Escherichia coli | shikimate 3-phosphate | — | 0.04 | 0.027 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant E341Q, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant H385A | Escherichia coli | phosphoenolpyruvate | — | 1.5 | 0.3 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant H385A, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant H385A | Escherichia coli | shikimate 3-phosphate | 0.41 | 0.09 | 4 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant H385A, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant K22A | Escherichia coli | phosphoenolpyruvate | — | — | 0.009 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant K22A, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant K22A | Escherichia coli | shikimate 3-phosphate | — | 2 | — | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant K22A, shikimate 3-phosphate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant K22R | Escherichia coli | phosphoenolpyruvate | — | 2.5 | 1.2 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant K22R, phosphoenolpyruvate |
| enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase)variant K22R | Escherichia coli | shikimate 3-phosphate | 3 | 0.19 | 16 | pH 7.5, 25 °C | PMID 19271774 | Open record: enolpyruvyl shikimate 3-phosphate synthase (AroA, EPSP synthase) variant K22R, shikimate 3-phosphate |
| EPSP synthase | Pseudomonas aeruginosa | 5-enolpyruvylshikimate-3-phosphate | 7.4 | 0.0022 | 3.4 × 10³ | pH 7, 25 °C | doi:10.1016/j.procbio.2006.11.006 | Open record: EPSP synthase, 5-enolpyruvylshikimate-3-phosphate |
| EPSP synthase | Pseudomonas aeruginosa | phosphate | 5.4 | 5.6 | 0.96 | pH 7, 25 °C | doi:10.1016/j.procbio.2006.11.006 | Open record: EPSP synthase, phosphate |
| EPSP synthasevariant G99A | Pseudomonas aeruginosa | 5-enolpyruvylshikimate-3-phosphate | 1.2 | 0.0019 | 660 | pH 7, 25 °C | doi:10.1016/j.procbio.2006.11.006 | Open record: EPSP synthase variant G99A, 5-enolpyruvylshikimate-3-phosphate |
| EPSP synthasevariant G99A | Pseudomonas aeruginosa | phosphate | 1 | 7.3 | 0.13 | pH 7, 25 °C | doi:10.1016/j.procbio.2006.11.006 | Open record: EPSP synthase variant G99A, phosphate |
| EPSP synthasevariant L104P | Pseudomonas aeruginosa | 5-enolpyruvylshikimate-3-phosphate | 2.7 | 0.0025 | 1.1 × 10³ | pH 7, 25 °C | doi:10.1016/j.procbio.2006.11.006 | Open record: EPSP synthase variant L104P, 5-enolpyruvylshikimate-3-phosphate |
| EPSP synthasevariant L104P | Pseudomonas aeruginosa | phosphate | 2.8 | 24.8 | 0.11 | pH 7, 25 °C | doi:10.1016/j.procbio.2006.11.006 | Open record: EPSP synthase variant L104P, phosphate |