EC 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase
TransferasesOpen in Browse
CatLog read 34 records for EC 2.5.1.54 from 5 papers, for 3 organisms. Names in these papers: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS), 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS) and 1 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 48 records for EC 2.5.1.54 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.5.1.54 in Browse.
Papers
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase | Neisseria meningitidis | D-erythrose 4-phosphate | — | 0.043 | 590 | pH 6.8 | PMID 23754471 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase | Neisseria meningitidis | D-erythrose 4-phosphatewith 300 microM L-Phe | — | 0.092 | 75 | pH 6.8 | PMID 23754471 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase | Neisseria meningitidis | phosphoenolpyruvate | 25.5 | 0.011 | 2.3 × 10³ | pH 6.8 | PMID 23754471 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase | Neisseria meningitidis | phosphoenolpyruvatewith 300 microM L-Phe | 6.9 | 0.021 | 330 | pH 6.8 | PMID 23754471 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthasevariant S213G | Neisseria meningitidis | D-erythrose 4-phosphate | — | 0.04 | 370 | pH 6.8 | PMID 23754471 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase variant S213G, D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthasevariant S213G | Neisseria meningitidis | D-erythrose 4-phosphatewith 300 microM L-Tyr | — | 0.021 | 290 | pH 6.8 | PMID 23754471 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase variant S213G, D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthasevariant S213G | Neisseria meningitidis | phosphoenolpyruvate | 14.8 | 0.0087 | 1.7 × 10³ | pH 6.8 | PMID 23754471 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase variant S213G, phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthasevariant S213G | Neisseria meningitidis | phosphoenolpyruvatewith 300 microM L-Tyr | 6 | 0.0054 | 1.11 × 10³ | pH 6.8 | PMID 23754471 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase variant S213G, phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS) | Neisseria meningitidis | D-erythrose 4-phosphate | — | 0.037 | — | pH 6.8, 25 °C | PMID 26828675 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS), D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS) | Neisseria meningitidis | phosphoenolpyruvate | 27.1 | 0.015 | 1.8 × 10³ calc. | pH 6.8, 25 °C | PMID 26828675 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS), phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS)variant R126S | Neisseria meningitidis | D-erythrose 4-phosphate | — | 0.0134 | — | pH 6.8, 25 °C | PMID 26828675 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS) variant R126S, D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS)variant R126S | Neisseria meningitidis | phosphoenolpyruvate | 12.6 | 0.025 | 500 calc. | pH 6.8, 25 °C | PMID 26828675 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (NmeDAH7PS) variant R126S, phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS) | Thermotoga maritima | D-erythrose 4-phosphate | — | 0.013 | 900 | pH 7.3 | PMID 23916814 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS), D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS) | Thermotoga maritima | phosphoenolpyruvate | 11.7 | 0.00485 | 2.4 × 10³ | pH 7.3 | PMID 23916814 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS), phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS)variant H29A | Thermotoga maritima | D-erythrose 4-phosphate | — | 0.03 | 580 | pH 7.3 | PMID 23916814 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS) variant H29A, D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS)variant H29A | Thermotoga maritima | phosphoenolpyruvate | 17.5 | 0.0128 | 1.4 × 10³ | pH 7.3 | PMID 23916814 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS) variant H29A, phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS)variant H29S/S31H | Thermotoga maritima | D-erythrose 4-phosphate | — | 0.028 | 500 | pH 7.3 | PMID 23916814 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS) variant H29S/S31H, D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS)variant H29S/S31H | Thermotoga maritima | phosphoenolpyruvate | 14.1 | 0.039 | 360 | pH 7.3 | PMID 23916814 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS) variant H29S/S31H, phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS)variant S31G | Thermotoga maritima | D-erythrose 4-phosphate | — | 0.033 | 430 | pH 7.3 | PMID 23916814 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS) variant S31G, D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS)variant S31G | Thermotoga maritima | phosphoenolpyruvate | 14.3 | 0.021 | 700 | pH 7.3 | PMID 23916814 | Open record: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (TmaDAH7PS) variant S31G, phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | 2-deoxy-D-erythrose 4-phosphate | 3 | 0.006 | 490 | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), 2-deoxy-D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | 2-deoxy-D-ribose 5-phosphate | 1.7 | 2.5 | 0.69 | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), 2-deoxy-D-ribose 5-phosphate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | D-arabinose 5-phosphate | 1.1 | 2.7 | 0.4 | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), D-arabinose 5-phosphate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | D-erythrose 4-phosphate | 1.4 | 0.009 | 160 | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), D-erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | D-ribose 5-phosphate | 2.5 | 1.58 | 1.6 | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), D-ribose 5-phosphate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | phosphoenolpyruvate20-600 µM PEP varied with 480 µM E4P; cosubstrate E4P | — | 0.093 | — | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | phosphoenolpyruvate20-600 µM PEP varied with 66 µM 2dE4P; cosubstrate 2dE4P | — | 0.033 | — | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | phosphoenolpyruvate20-600 µM PEP varied with 9 mM A5P; cosubstrate A5P | — | 0.062 | — | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | phosphoenolpyruvate20-600 µM PEP varied with 4.5 mM R5P; cosubstrate R5P | — | 0.036 | — | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS) | Pyrococcus furiosus | phosphoenolpyruvate28-280 µM PEP varied with 4.5 mM 2dR5P; cosubstrate 2dR5P | — | 0.035 | — | pH 6.8, 60 °C | PMID 16142893 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (Pf-DAH7PS), phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (PfuDAH7PS) | Pyrococcus furiosus | erythrose 4-phosphate | — | 0.092 | 60 | pH 7.5, 60 °C | PMID 24239948 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (PfuDAH7PS), erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (PfuDAH7PS) | Pyrococcus furiosus | phosphoenolpyruvate | 5.5 | 0.112 | 49 | pH 7.5, 60 °C | PMID 24239948 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (PfuDAH7PS), phosphoenolpyruvate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (PfuDAH7PS)variant I181D | Pyrococcus furiosus | erythrose 4-phosphate | — | 0.071 | 210 | pH 7.5, 60 °C | PMID 24239948 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (PfuDAH7PS) variant I181D, erythrose 4-phosphate |
| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (PfuDAH7PS)variant I181D | Pyrococcus furiosus | phosphoenolpyruvate | 14.9 | 0.066 | 220 | pH 7.5, 60 °C | PMID 24239948 | Open record: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (PfuDAH7PS) variant I181D, phosphoenolpyruvate |