CatLogenzyme kinetics catalog

EC 2.5.1.78: 6,7-dimethyl-8-ribityllumazine synthase

TransferasesOpen in Browse

CatLog read 51 records for EC 2.5.1.78 from 2 papers, for 2 organisms. Names in these papers: 6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase), 6,7-dimethyl-8-ribityllumazine synthase.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 28 records for EC 2.5.1.78 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.5.1.78 in Browse.

Papers

PaperOrganismsRecords
Enzyme catalysis via control of activation entropy: site-directed mutagenesis of 6,7-dimethyl-8-ribityllumazine synthaseBacillus subtilis37
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombeSchizosaccharomyces pombe14

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
6,7-dimethyl-8-ribityllumazine synthaseSchizosaccharomyces pombe3,4-dihydroxy-2-butanone 4-phosphate—0.067—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthaseSchizosaccharomyces pombe5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.005—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27FSchizosaccharomyces pombe3,4-dihydroxy-2-butanone 4-phosphate—0.065—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27FSchizosaccharomyces pombe5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.003—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27GSchizosaccharomyces pombe3,4-dihydroxy-2-butanone 4-phosphate—0.168—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27GSchizosaccharomyces pombe5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.43—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27HSchizosaccharomyces pombe3,4-dihydroxy-2-butanone 4-phosphate—0.145—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27HSchizosaccharomyces pombe5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.4—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27ISchizosaccharomyces pombe3,4-dihydroxy-2-butanone 4-phosphate—0.137—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27ISchizosaccharomyces pombe5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.23—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27SSchizosaccharomyces pombe3,4-dihydroxy-2-butanone 4-phosphate—0.187—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27SSchizosaccharomyces pombe5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.46—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27YSchizosaccharomyces pombe3,4-dihydroxy-2-butanone 4-phosphate—0.086—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthasevariant W27YSchizosaccharomyces pombe5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.003—pH 7, 37 °CPMID 11856310Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)Bacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.05570.054661.02 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)Bacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.00857—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant A56SBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.04530.070150.646 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant A56SBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.0042—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant D138ABacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.0510.063640.80 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant D138ABacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.00996—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant E58QBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.03910.1460.268 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant E58QBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.1732—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F113SBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.00380.066450.057 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F113SBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.2785—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F22DBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.00810.67480.012 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F22SBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.02630.13730.191 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F22SBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.1405—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F22VBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.01470.12440.118 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F22VBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.01072—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F22WBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.02440.059830.408 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F22WBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.00612—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F57SBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.02440.080070.305 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant F57SBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.03449—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant H88ABacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.00670.060120.11 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant H88ABacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.1465—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant H88KBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.00220.042190.052 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant H88KBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.05557—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant K131NBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.00540.28250.019 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant K131NBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.03552—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant K131RBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.01660.049980.332 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant K131RBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.01379—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant K135ABacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.01220.16660.0732 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant K135ABacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.01148—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant N23SBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.01220.058080.210 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant N23SBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.01191—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant R127HBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.03883.1380.0124 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant R127HBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.08492—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant S142LBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.03470.090520.383 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant S142LBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.01148—pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant T80VBacillus subtilis3,4-dihydroxy-2-butanone 4-phosphate0.03070.041960.732 calc.pH 7, 37 °CPMID 12581640Open
6,7-dimethyl-8-ribityllumazine synthase (lumazine synthase)variant T80VBacillus subtilis5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione—0.00406—pH 7, 37 °CPMID 12581640Open