EC 2.6.1.19: 4-aminobutyrate-2-oxoglutarate transaminase
TransferasesOpen in Browse
CatLog read 61 records for EC 2.6.1.19 from 2 papers, for 2 organisms. Names in these papers: γ-aminobutyrate aminotransferase (GABA-AT), MdGABA-T1, MdGABA-T2.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 88 records for EC 2.6.1.19 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.6.1.19 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Kinetic and crystallographic analysis of active site mutants of Escherichia coli gamma-aminobutyrate aminotransferase | Escherichia coli | 53 |
| doi:10.1016/j.postharvbio.2012.08.005 | Malus × domestica | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| MdGABA-T1 | Malus × domestica | glyoxylate | 2.6 | 0.039 | 66.6 | pH 9, 25 °C | doi:10.1016/j.postharvbio.2012.08.005 | Open record: MdGABA-T1, glyoxylate |
| MdGABA-T1 | Malus × domestica | pyruvate | 2.7 | 0.023 | 116 | pH 9, 25 °C | doi:10.1016/j.postharvbio.2012.08.005 | Open record: MdGABA-T1, pyruvate |
| MdGABA-T1 | Malus × domestica | γ-aminobutyratecosubstrate pyruvate | 2.6 | 0.165 | 16.1 | pH 9, 25 °C | doi:10.1016/j.postharvbio.2012.08.005 | Open record: MdGABA-T1, γ-aminobutyrate |
| MdGABA-T1 | Malus × domestica | γ-aminobutyratecosubstrate glyoxylate | 2.7 | 0.135 | 19.5 | pH 9, 25 °C | doi:10.1016/j.postharvbio.2012.08.005 | Open record: MdGABA-T1, γ-aminobutyrate |
| MdGABA-T2 | Malus × domestica | glyoxylate | 0.74 | 0.0165 | 45.7 | pH 9, 25 °C | doi:10.1016/j.postharvbio.2012.08.005 | Open record: MdGABA-T2, glyoxylate |
| MdGABA-T2 | Malus × domestica | pyruvate | 0.8 | 0.0188 | 42.7 | pH 9, 25 °C | doi:10.1016/j.postharvbio.2012.08.005 | Open record: MdGABA-T2, pyruvate |
| MdGABA-T2 | Malus × domestica | γ-aminobutyratecosubstrate pyruvate | 0.84 | 0.0773 | 10.9 | pH 9, 25 °C | doi:10.1016/j.postharvbio.2012.08.005 | Open record: MdGABA-T2, γ-aminobutyrate |
| MdGABA-T2 | Malus × domestica | γ-aminobutyratecosubstrate glyoxylate | 1 | 0.0997 | 10.4 | pH 9, 25 °C | doi:10.1016/j.postharvbio.2012.08.005 | Open record: MdGABA-T2, γ-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT) | Escherichia coli | 2-oxoglutarateping-pong GABA/α-KG transamination; global fit | — | 1.07 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT), 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT) | Escherichia coli | 2-oxoglutarateL-aspartate/α-KG transamination; cosubstrate L-aspartate | — | 0.8 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT), 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT) | Escherichia coli | D,L-α-methylaspartate | 8.6 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT), D,L-α-methylaspartate |
| γ-aminobutyrate aminotransferase (GABA-AT) | Escherichia coli | D,L-α-methylglutamate | 9.2 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT), D,L-α-methylglutamate |
| γ-aminobutyrate aminotransferase (GABA-AT) | Escherichia coli | D-glutamate | 1.5 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT), D-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT) | Escherichia coli | gamma-aminobutyrate | 47.4 | 5.8 | 8.172 | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT), gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT) | Escherichia coli | L-aspartate | 0.016 | 150 | 1.1 × 10⁻⁴ calc. | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT), L-aspartate |
| γ-aminobutyrate aminotransferase (GABA-AT) | Escherichia coli | L-glutamate | 6 × 10⁻⁵ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT), L-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S | Escherichia coli | 2-oxoglutarateping-pong GABA/α-KG transamination; global fit | — | 0.0021 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S, 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S | Escherichia coli | 2-oxoglutarateL-aspartate/α-KG transamination; cosubstrate L-aspartate | — | 0.0018 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S, 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S | Escherichia coli | D,L-α-methylglutamate | 2.4 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S, D,L-α-methylglutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S | Escherichia coli | D-glutamate | 1.8 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S, D-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S | Escherichia coli | gamma-aminobutyrate | 0.56 | 86 | 0.0065 | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S | Escherichia coli | L-aspartate | 0.073 | 56 | 0.0013 calc. | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S, L-aspartate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S | Escherichia coli | L-glutamate | 1.6 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S, L-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G | Escherichia coli | D,L-α-methylglutamate | 1.1 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G, D,L-α-methylglutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G | Escherichia coli | gamma-aminobutyrate | 0.003 | — | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G | Escherichia coli | L-glutamate | 9 × 10⁻⁵ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G, L-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77K | Escherichia coli | 2-oxoglutarate | — | 0.72 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77K, 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77K | Escherichia coli | D,L-α-methylaspartate | 3.8 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77K, D,L-α-methylaspartate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77K | Escherichia coli | D,L-α-methylglutamate | 0.00104 | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77K, D,L-α-methylglutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77K | Escherichia coli | D-glutamate | 6.9 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77K, D-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77K | Escherichia coli | gamma-aminobutyrate | 0.25 | 5.9 | 0.042 | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77K, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77K | Escherichia coli | L-glutamate | 5.2 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77K, L-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77R | Escherichia coli | D,L-α-methylaspartate | 1.4 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77R, D,L-α-methylaspartate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77R | Escherichia coli | D-glutamate | 1.1 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77R, D-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77R | Escherichia coli | gamma-aminobutyrate | 5 × 10⁻⁴ | — | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77R, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50G/C77R | Escherichia coli | L-glutamate | 1.9 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50G/C77R, L-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80D | Escherichia coli | D,L-α-methylaspartate | 7.4 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80D, D,L-α-methylaspartate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80D | Escherichia coli | D,L-α-methylglutamate | 0.0017 | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80D, D,L-α-methylglutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80D | Escherichia coli | D-glutamate | 9.8 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80D, D-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80D | Escherichia coli | gamma-aminobutyrate | 2.3 × 10⁻⁴ | — | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80D, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80D | Escherichia coli | L-glutamate | 6.1 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80D, L-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80T | Escherichia coli | 2-oxoglutarate | — | 0.063 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80T, 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80T | Escherichia coli | D,L-α-methylaspartate | 1.4 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80T, D,L-α-methylaspartate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80T | Escherichia coli | D-glutamate | 1.5 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80T, D-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50H/V80T | Escherichia coli | gamma-aminobutyrate | 0.106 | 146 | 7.3 × 10⁻⁴ | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50H/V80T, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50N/V80D | Escherichia coli | gamma-aminobutyrate | 0.0075 | — | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50N/V80D, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50N/V80T | Escherichia coli | D,L-α-methylaspartate | 1.4 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50N/V80T, D,L-α-methylaspartate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50N/V80T | Escherichia coli | D,L-α-methylglutamate | 2.8 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50N/V80T, D,L-α-methylglutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50N/V80T | Escherichia coli | gamma-aminobutyrate | 0.0058 | — | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50N/V80T, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50N/V80T | Escherichia coli | L-glutamate | 1.9 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50N/V80T, L-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant E211S/I50Q/G295Y/V241A | Escherichia coli | gamma-aminobutyrate | 0.004 | — | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant E211S/I50Q/G295Y/V241A, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant I50Q | Escherichia coli | 2-oxoglutarate | — | 46 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant I50Q, 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant I50Q | Escherichia coli | D,L-α-methylaspartate | 4 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant I50Q, D,L-α-methylaspartate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant I50Q | Escherichia coli | D,L-α-methylglutamate | 7 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant I50Q, D,L-α-methylglutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant I50Q | Escherichia coli | D-glutamate | 1 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant I50Q, D-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant I50Q | Escherichia coli | gamma-aminobutyrate | 13.5 | 68 | 0.199 | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant I50Q, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant I50Q | Escherichia coli | L-glutamate | 2.2 × 10⁻⁴ | — | — | 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant I50Q, L-glutamate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant I50Q/G295Y | Escherichia coli | 2-oxoglutarate | — | 0.78 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant I50Q/G295Y, 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant I50Q/G295Y | Escherichia coli | gamma-aminobutyrate | 0.028 | 4.7 | 0.0059 | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant I50Q/G295Y, gamma-aminobutyrate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant V241A | Escherichia coli | 2-oxoglutarate | — | 0.13 | — | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant V241A, 2-oxoglutarate |
| γ-aminobutyrate aminotransferase (GABA-AT)variant V241A | Escherichia coli | gamma-aminobutyrate | 1.93 | 30 | 0.064 | pH 7.8, 25 °C | PMID 15723541 | Open record: γ-aminobutyrate aminotransferase (GABA-AT) variant V241A, gamma-aminobutyrate |