CatLogenzyme kinetics catalog

EC 2.6.1.62: adenosylmethionine-8-amino-7-oxononanoate transaminase

TransferasesOpen in Browse

CatLog read 19 records for EC 2.6.1.62 from 2 papers, for 2 organisms. Names in these papers: 7,8-diaminopelargonic acid synthase (DAPA synthase), 7,8-diaminopelargonic acid synthase (DAPAS).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 42 records for EC 2.6.1.62 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.6.1.62 in Browse.

Papers

PaperOrganismsRecords
Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysisEscherichia coli18
Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetaseMycobacterium tuberculosis1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
7,8-diaminopelargonic acid synthase (DAPA synthase)Escherichia coli7,8-diaminopelargonic acid0.790.001790 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)Escherichia coliS-adenosyl-(5')-3-methylthiopropylamine0.0160.750.021 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)Escherichia coliS-adenosyl-L-methionineapparent Km0.0160.30.053 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)Escherichia coliS-adenosyl-L-methionine——0.053pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253AEscherichia coli7,8-diaminopelargonic acid1.30.0022590 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253KEscherichia coli7,8-diaminopelargonic acid1.38 × 10⁻⁴1.6 × 10³ calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253KEscherichia coliS-adenosyl-(5')-3-methylthiopropylamine0.0160.10.16 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253KEscherichia coliS-adenosyl-L-methionineapparent Km0.0090.010.90 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253KEscherichia coliS-adenosyl-L-methionine——0.9pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253MEscherichia coli7,8-diaminopelargonic acid0.676 × 10⁻⁴1.1 × 10³ calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253QEscherichia coli7,8-diaminopelargonic acid1.70.00141.2 × 10³ calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253QEscherichia coliS-adenosyl-L-methionineapparent Km0.0740.1050.70 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant R253QEscherichia coliS-adenosyl-L-methionine——0.7pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant Y144FEscherichia coli7,8-diaminopelargonic acid0.040.150.27 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant Y144FEscherichia coliS-adenosyl-L-methionine——0.016pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant Y17FEscherichia coli7,8-diaminopelargonic acid0.0120.020.60 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant Y17FEscherichia coliS-adenosyl-L-methionineapparent Km0.00350.0630.056 calc.pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPA synthase)variant Y17FEscherichia coliS-adenosyl-L-methionine——0.056pH 9PMID 14756557Open
7,8-diaminopelargonic acid synthase (DAPAS)Mycobacterium tuberculosissinefungin0.0090.70.013pH 8.5PMID 20565114Open