CatLogenzyme kinetics catalog

EC 2.6.1.85: aminodeoxychorismate synthase

TransferasesOpen in Browse

CatLog read 14 records for EC 2.6.1.85 from 2 papers, for 2 organisms. Names in these papers: 4-amino-4-deoxychorismate synthase (ADCS, PabB), aminodeoxychorismate synthase (AtADCS).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 23 records for EC 2.6.1.85 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.6.1.85 in Browse.

Papers

PaperOrganismsRecords
Conservation of mechanism in three chorismate-utilizing enzymesEscherichia coli9
Folate synthesis in plants: purification, kinetic properties, and inhibition of aminodeoxychorismate synthaseArabidopsis thaliana5

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
4-amino-4-deoxychorismate synthase (ADCS, PabB)Escherichia coliammonium0.0321452.2 × 10⁻⁴ calc.pH 8.5, 25 °CPMID 14982443Open
4-amino-4-deoxychorismate synthase (ADCS, PabB)Escherichia colichorismatecosubstrate glutamine (PabA + Gln nitrogen source)0.530.01341 calc.pH 8.5, 25 °CPMID 14982443Open
4-amino-4-deoxychorismate synthase (ADCS, PabB)Escherichia colichorismate200 mM NH4+ as nitrogen source (100 mM (NH4)2SO4); no PabA0.0320.0580.55 calc.pH 8.5, 25 °CPMID 14982443Open
4-amino-4-deoxychorismate synthase (ADCS, PabB)variant K274AEscherichia coliammonium0.0331692.0 × 10⁻⁴ calc.pH 8.5, 25 °CPMID 14982443Open
4-amino-4-deoxychorismate synthase (ADCS, PabB)variant K274AEscherichia colichorismatePabA + glutamine as nitrogen source0.002——pH 8.5, 25 °CPMID 14982443Open
4-amino-4-deoxychorismate synthase (ADCS, PabB)variant K274AEscherichia colichorismate200 mM NH4+ as nitrogen source (100 mM (NH4)2SO4); no PabA0.0260.0970.27 calc.pH 8.5, 25 °CPMID 14982443Open
4-amino-4-deoxychorismate synthase (ADCS, PabB)variant K274AEscherichia colichorismatePabA + glutamine + 200 mM NH4+ as nitrogen sources0.01——pH 8.5, 25 °CPMID 14982443Open
4-amino-4-deoxychorismate synthase (ADCS, PabB)variant K274REscherichia colichorismatePabA + glutamine as nitrogen source8.3 × 10⁻⁴——pH 8.5, 25 °CPMID 14982443Open
4-amino-4-deoxychorismate synthase (ADCS, PabB)variant K274REscherichia colichorismate200 mM NH4+ as nitrogen source; no PabA9.8 × 10⁻⁵——pH 8.5, 25 °CPMID 14982443Open
aminodeoxychorismate synthase (AtADCS)Arabidopsis thalianachorismate0.25 mM L-glutamine; cosubstrate L-glutamine (0.25 mM)0.0450.002816pH 8, 37 °CPMID 16466344Open
aminodeoxychorismate synthase (AtADCS)Arabidopsis thalianachorismate5 mM L-glutamine; cosubstrate L-glutamine (5 mM)0.150.0013100pH 8, 37 °CPMID 16466344Open
aminodeoxychorismate synthase (AtADCS)Arabidopsis thalianaL-glutamineglutaminase reaction without chorismate0.0452.20.02pH 8, 37 °CPMID 16466344Open
aminodeoxychorismate synthase (AtADCS)Arabidopsis thalianaL-glutamine50 µM chorismate; cosubstrate chorismate (50 µM)0.150.60.25pH 8, 37 °CPMID 16466344Open
aminodeoxychorismate synthase (AtADCS)Arabidopsis thalianaNH30.116001.8 × 10⁻⁴pH 8, 37 °CPMID 16466344Open