EC 2.7.1.136: macrolide 2'-kinase
TransferasesOpen in Browse
CatLog read 8 records for EC 2.7.1.136 from 1 paper, for 1 organism. Names in these papers: MphB.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 3 records for EC 2.7.1.136 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.1.136 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The evolution of substrate discrimination in macrolide antibiotic resistance enzymes | Escherichia coli | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| MphB | Escherichia coli | Azithromycin | 0.189 | 0.0029 | 66 | pH 7.5 | PMID 29317655 | Open record: MphB, Azithromycin |
| MphB | Escherichia coli | Erythromycin | 0.0412 | 0.0016 | 25 | pH 7.5 | PMID 29317655 | Open record: MphB, Erythromycin |
| MphB | Escherichia coli | GTP | 0.602 | 0.0083 | 73 | pH 7.5 | PMID 29317655 | Open record: MphB, GTP |
| MphB | Escherichia coli | Josamycin | 1.2 | 8.3 × 10⁻⁴ | 1.5 × 10³ | pH 7.5 | PMID 29317655 | Open record: MphB, Josamycin |
| MphB | Escherichia coli | Roxithromycin | 0.025 | 0.0015 | 17 | pH 7.5 | PMID 29317655 | Open record: MphB, Roxithromycin |
| MphB | Escherichia coli | Spiramycin | 0.11 | 0.002 | 55 | pH 7.5 | PMID 29317655 | Open record: MphB, Spiramycin |
| MphB | Escherichia coli | Telithromycin | 0.77 | 0.0066 | 120 | pH 7.5 | PMID 29317655 | Open record: MphB, Telithromycin |
| MphB | Escherichia coli | Tylosin | 0.07 | 0.0018 | 94 | pH 7.5 | PMID 29317655 | Open record: MphB, Tylosin |