CatLogenzyme kinetics catalog

EC 2.7.1.60: N-acylmannosamine kinase

TransferasesOpen in Browse

CatLog read 33 records for EC 2.7.1.60 from 4 papers, for 3 organisms. Names in these papers: N-acetyl-D-mannosamine kinase (NanK), N-acetylmannosamine kinase (SaNanK), NanK (N-acetyl-D-mannosamine kinase), N-acetylglucosamine kinase NagK.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 11 records for EC 2.7.1.60 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.1.60 in Browse.

Papers

PaperOrganismsRecords
Divergent evolution of function in the ROK sugar kinase superfamily: role of enzyme loops in substrate specificityEscherichia coli17
The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureusStaphylococcus aureus9
Identifying latent enzyme activities: substrate ambiguity within modern bacterial sugar kinasesEscherichia coli4
Evaluation and Comparison of Candida albicans vs Mammalian 6-O-Phospho-Kinases: Substrate Specificity and ApplicationsHomo sapiens3

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
N-acetyl-D-mannosamine kinase (NanK)Escherichia coli1,5-anhydroglucitol——0.0017pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)Escherichia coliATP5 mM phosphoenolpyruvate; 5 mM KCl; 6-26 mM MgCl2—0.26—pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)Escherichia coliATP8.5 mM MgCl2; cosubstrate D-glucose—1.2—pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)Escherichia coliD-glucose22201.1pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)Escherichia coliD-mannose25840.3pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)Escherichia coliN-acetyl-D-mannosamine560.36150pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant L84PEscherichia coli1,5-anhydroglucitol——0.01pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant L84PEscherichia coliATP5 mM phosphoenolpyruvate; 5 mM KCl; 6-26 mM MgCl2—0.084—pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant L84PEscherichia coliATP8.5 mM MgCl2; cosubstrate D-glucose—0.92—pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant L84PEscherichia coliD-glucose846.413pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant L84PEscherichia coliD-mannose62232.8pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant L84PEscherichia coliN-acetyl-D-mannosamine180.2378pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant L84P/V138MEscherichia coliD-glucose——5.3pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant V138MEscherichia coliATP5 mM phosphoenolpyruvate; 5 mM KCl; 6-26 mM MgCl2—0.11—pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant V138MEscherichia coliATP8.5 mM MgCl2; cosubstrate D-glucose—0.63—pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant V138MEscherichia coliD-glucose608.67pH 7.6, 25 °CPMID 17979299Open
N-acetyl-D-mannosamine kinase (NanK)variant V138MEscherichia coliN-acetyl-D-mannosamine200.16120pH 7.6, 25 °CPMID 17979299Open
N-acetylglucosamine kinase NagKHomo sapiensN-acetylglucosamine3.60.06555.325 °CPMID 39661445Open
N-acetylglucosamine kinase NagKHomo sapiensN-acetylglucosamine3.520.12129.137 °CPMID 39661445Open
N-acetylglucosamine kinase NagKHomo sapiensN-acetylmuramic acid0.680.3571.937 °CPMID 39661445Open
N-acetylmannosamine kinase (SaNanK)Staphylococcus aureusadenosine 5'-triphosphate—0.73—pH 8.5, 25 °CPMID 31949045Open
N-acetylmannosamine kinase (SaNanK)Staphylococcus aureusglucose60154pH 8.5, 25 °CPMID 31949045Open
N-acetylmannosamine kinase (SaNanK)Staphylococcus aureusN-acetyl-D-glucosamine23.40.2690pH 8.5, 25 °CPMID 31949045Open
N-acetylmannosamine kinase (SaNanK)Staphylococcus aureusN-acetylmannosamine2630.3871pH 8.5, 25 °CPMID 31949045Open
N-acetylmannosamine kinase (SaNanK)variant R164KStaphylococcus aureusN-acetylmannosamine3.20.2612 calc.pH 8.5, 25 °CPMID 31949045Open
N-acetylmannosamine kinase (SaNanK)variant Y160AStaphylococcus aureusN-acetyl-D-glucosamine17.80.057310pH 8.5, 25 °CPMID 31949045Open
N-acetylmannosamine kinase (SaNanK)variant Y160AStaphylococcus aureusN-acetylmannosamine2231.34167pH 8.5, 25 °CPMID 31949045Open
N-acetylmannosamine kinase (SaNanK)variant Y160FStaphylococcus aureusN-acetyl-D-glucosamine19.10.049390pH 8.5, 25 °CPMID 31949045Open
N-acetylmannosamine kinase (SaNanK)variant Y160FStaphylococcus aureusN-acetylmannosamine2161.27171pH 8.5, 25 °CPMID 31949045Open
NanK (N-acetyl-D-mannosamine kinase)Escherichia coliadenosine 5'-triphosphatecosubstrate D-glucose—2.9—pH 7.6, 25 °CPMID 15157072Open
NanK (N-acetyl-D-mannosamine kinase)Escherichia coliadenosine 5'-triphosphatecosubstrate N-acetyl-D-mannosamine—0.51—pH 7.6, 25 °CPMID 15157072Open
NanK (N-acetyl-D-mannosamine kinase)Escherichia coliD-glucose9.1180.51pH 7.6, 25 °CPMID 15157072Open
NanK (N-acetyl-D-mannosamine kinase)Escherichia coliN-acetyl-D-mannosamine830.31270pH 7.6, 25 °CPMID 15157072Open