EC 2.7.4.4: nucleoside-phosphate kinase
TransferasesOpen in Browse
CatLog read 15 records for EC 2.7.4.4 from 2 papers, for 2 organisms. Names in these papers: adenylate kinase, adenylate kinase 1 (AK1).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 7 records for EC 2.7.4.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.4.4 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Mechanism of adenylate kinase. The conserved aspartates 140 and 141 are important for transition state stabilization instead of substrate-induced conformational changes | Gallus gallus | 14 |
| Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite | Homo sapiens | 1 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| adenylate kinase | Gallus gallus | 2'-deoxyadenosine 5'-monophosphate | 87 | 2.1 | 41 | PMID 8132532 | Open record: adenylate kinase, 2'-deoxyadenosine 5'-monophosphate | |
| adenylate kinase | Gallus gallus | adenosine 5'-monophosphate | 500 | 0.15 | 3.3 × 10³ | PMID 8132532 | Open record: adenylate kinase, adenosine 5'-monophosphate | |
| adenylate kinasevariant D140A | Gallus gallus | 2'-deoxyadenosine 5'-monophosphate | 0.1 | 3.9 | 0.025 | PMID 8132532 | Open record: adenylate kinase variant D140A, 2'-deoxyadenosine 5'-monophosphate | |
| adenylate kinasevariant D140A | Gallus gallus | adenosine 5'-monophosphateboth MgATP and AMP varied | 8.3 | 0.55 | 15 | PMID 8132532 | Open record: adenylate kinase variant D140A, adenosine 5'-monophosphate | |
| adenylate kinasevariant D140A | Gallus gallus | adenosine 5'-monophosphate | 6 | 1.4 | 4.3 | PMID 8132532 | Open record: adenylate kinase variant D140A, adenosine 5'-monophosphate | |
| adenylate kinasevariant D140A | Gallus gallus | MgATP | — | 0.25 | 33 | PMID 8132532 | Open record: adenylate kinase variant D140A, MgATP | |
| adenylate kinasevariant D141A | Gallus gallus | 2'-deoxyadenosine 5'-monophosphate | 0.27 | 10.3 | 0.026 | PMID 8132532 | Open record: adenylate kinase variant D141A, 2'-deoxyadenosine 5'-monophosphate | |
| adenylate kinasevariant D141A | Gallus gallus | adenosine 5'-monophosphateboth MgATP and AMP varied | 38 | 0.84 | 45 | PMID 8132532 | Open record: adenylate kinase variant D141A, adenosine 5'-monophosphate | |
| adenylate kinasevariant D141A | Gallus gallus | adenosine 5'-monophosphate | 22 | 1.8 | 12 | PMID 8132532 | Open record: adenylate kinase variant D141A, adenosine 5'-monophosphate | |
| adenylate kinasevariant D141A | Gallus gallus | MgATP | — | 0.51 | 74 | PMID 8132532 | Open record: adenylate kinase variant D141A, MgATP | |
| adenylate kinasevariant R132M/D141A | Gallus gallus | adenosine 5'-monophosphate | 0.04 | 1.8 | 0.023 | PMID 8132532 | Open record: adenylate kinase variant R132M/D141A, adenosine 5'-monophosphate | |
| adenylate kinasevariant R132M/D141A | Gallus gallus | MgATP | — | 1.2 | — | PMID 8132532 | Open record: adenylate kinase variant R132M/D141A, MgATP | |
| adenylate kinasevariant R138M/D140A | Gallus gallus | adenosine 5'-monophosphate | 0.04 | 1.4 | 0.028 | PMID 8132532 | Open record: adenylate kinase variant R138M/D140A, adenosine 5'-monophosphate | |
| adenylate kinasevariant R138M/D140A | Gallus gallus | MgATP | — | 0.3 | 0.133 | PMID 8132532 | Open record: adenylate kinase variant R138M/D140A, MgATP | |
| adenylate kinase 1 (AK1) | Homo sapiens | adenosine monophosphate | 24.95 | 0.756 | 33 | pH 7.5, 37 °C | PMID 42363837 | Open record: adenylate kinase 1 (AK1), adenosine monophosphate |