EC 2.7.4.6: nucleoside-diphosphate kinase

TransferasesOpen in Browse

CatLog read 74 records for EC 2.7.4.6 from 8 papers, for 7 organisms. Names in these papers: adenylate kinase, UMP/CMP kinase 1 (UMP/CMPK1), mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3), nucleoside diphosphate kinase and 7 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 60 records for EC 2.7.4.6 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.4.6 in Browse.

Papers

Papers with records for EC 2.7.4.6
Paper	Organisms	Records
Physiological and biochemical characterization of three nucleoside diphosphate kinase isozymes from rice (Oryza sativa L.)	Oryza sativa	18
Mechanism of adenylate kinase. The conserved aspartates 140 and 141 are important for transition state stabilization instead of substrate-induced conformational changes	Gallus gallus	14
Recombinant rat nucleoside diphosphate kinase isoforms (alpha and beta): purification, properties and application to immunological detection of native isoforms in rat tissues	Rattus norvegicus	12
Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1	Homo sapiens	11
Structure and mutational analysis of a plant mitochondrial nucleoside diphosphate kinase. Identification of residues involved in serine phosphorylation and oligomerization	Pisum sativum	6
Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase	Aspergillus fumigatus	6
Kinetic studies of yeast nucleoside diphosphate kinase	yeast	6
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite	Homo sapiens	1

Records

Records for EC 2.7.4.6 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
adenylate kinase	Gallus gallus	2'-deoxyadenosine 5'-monophosphate	87	2.1	41		PMID 8132532	Open record: adenylate kinase, 2'-deoxyadenosine 5'-monophosphate
adenylate kinase	Gallus gallus	adenosine 5'-monophosphate	500	0.15	3.3 × 10³		PMID 8132532	Open record: adenylate kinase, adenosine 5'-monophosphate
adenylate kinasevariant D140A	Gallus gallus	2'-deoxyadenosine 5'-monophosphate	0.1	3.9	0.025		PMID 8132532	Open record: adenylate kinase variant D140A, 2'-deoxyadenosine 5'-monophosphate
adenylate kinasevariant D140A	Gallus gallus	adenosine 5'-monophosphateboth MgATP and AMP varied	8.3	0.55	15		PMID 8132532	Open record: adenylate kinase variant D140A, adenosine 5'-monophosphate
adenylate kinasevariant D140A	Gallus gallus	adenosine 5'-monophosphate	6	1.4	4.3		PMID 8132532	Open record: adenylate kinase variant D140A, adenosine 5'-monophosphate
adenylate kinasevariant D140A	Gallus gallus	MgATP	—	0.25	33		PMID 8132532	Open record: adenylate kinase variant D140A, MgATP
adenylate kinasevariant D141A	Gallus gallus	2'-deoxyadenosine 5'-monophosphate	0.27	10.3	0.026		PMID 8132532	Open record: adenylate kinase variant D141A, 2'-deoxyadenosine 5'-monophosphate
adenylate kinasevariant D141A	Gallus gallus	adenosine 5'-monophosphateboth MgATP and AMP varied	38	0.84	45		PMID 8132532	Open record: adenylate kinase variant D141A, adenosine 5'-monophosphate
adenylate kinasevariant D141A	Gallus gallus	adenosine 5'-monophosphate	22	1.8	12		PMID 8132532	Open record: adenylate kinase variant D141A, adenosine 5'-monophosphate
adenylate kinasevariant D141A	Gallus gallus	MgATP	—	0.51	74		PMID 8132532	Open record: adenylate kinase variant D141A, MgATP
adenylate kinasevariant R132M/D141A	Gallus gallus	adenosine 5'-monophosphate	0.04	1.8	0.023		PMID 8132532	Open record: adenylate kinase variant R132M/D141A, adenosine 5'-monophosphate
adenylate kinasevariant R132M/D141A	Gallus gallus	MgATP	—	1.2	—		PMID 8132532	Open record: adenylate kinase variant R132M/D141A, MgATP
adenylate kinasevariant R138M/D140A	Gallus gallus	adenosine 5'-monophosphate	0.04	1.4	0.028		PMID 8132532	Open record: adenylate kinase variant R138M/D140A, adenosine 5'-monophosphate
adenylate kinasevariant R138M/D140A	Gallus gallus	MgATP	—	0.3	0.133		PMID 8132532	Open record: adenylate kinase variant R138M/D140A, MgATP
adenylate kinase 1 (AK1)	Homo sapiens	adenosine monophosphate	24.95	0.756	33	pH 7.5, 37 °C	PMID 42363837	Open record: adenylate kinase 1 (AK1), adenosine monophosphate
mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3)	Pisum sativum	2'-deoxycytidine 5'-diphosphate	106	0.2	530 calc.	22 °C	PMID 15466238	Open record: mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3), 2'-deoxycytidine 5'-diphosphate
mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3)	Pisum sativum	thymidine 5'-diphosphate	147	0.1	1.5 × 10³ calc.	22 °C	PMID 15466238	Open record: mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3), thymidine 5'-diphosphate
mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3)variant S119A	Pisum sativum	2'-deoxycytidine 5'-diphosphate	105	0.28	380 calc.	22 °C	PMID 15466238	Open record: mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3) variant S119A, 2'-deoxycytidine 5'-diphosphate
mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3)variant S119A	Pisum sativum	thymidine 5'-diphosphate	120	0.08	1.5 × 10³ calc.	22 °C	PMID 15466238	Open record: mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3) variant S119A, thymidine 5'-diphosphate
mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3)variant S69A	Pisum sativum	2'-deoxycytidine 5'-diphosphate	9	0.09	100 calc.	22 °C	PMID 15466238	Open record: mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3) variant S69A, 2'-deoxycytidine 5'-diphosphate
mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3)variant S69A	Pisum sativum	thymidine 5'-diphosphate	17	0.07	240 calc.	22 °C	PMID 15466238	Open record: mitochondrial nucleoside diphosphate kinase (mtNDPK, NDPK-3) variant S69A, thymidine 5'-diphosphate
nucleoside diphosphate kinase	yeast	magnesium complex of ADP	—	0.05	—	pH 8, 30 °C	PMID 5793714	Open record: nucleoside diphosphate kinase, magnesium complex of ADP
nucleoside diphosphate kinase	yeast	magnesium complex of ATP	—	0.31	—	pH 8, 30 °C	PMID 5793714	Open record: nucleoside diphosphate kinase, magnesium complex of ATP
nucleoside diphosphate kinase	yeast	magnesium complex of UDPTable I	—	0.043	—	pH 8, 30 °C	PMID 5793714	Open record: nucleoside diphosphate kinase, magnesium complex of UDP
nucleoside diphosphate kinase	yeast	magnesium complex of UDPin the text	1 × 10⁴	—	—	pH 8, 30 °C	PMID 5793714	Open record: nucleoside diphosphate kinase, magnesium complex of UDP
nucleoside diphosphate kinase	yeast	magnesium complex of UDPkcat per active site; in the text	2.5 × 10³	—	—	pH 8, 30 °C	PMID 5793714	Open record: nucleoside diphosphate kinase, magnesium complex of UDP
nucleoside diphosphate kinase	yeast	magnesium complex of UTP	—	0.25	—	pH 8, 30 °C	PMID 5793714	Open record: nucleoside diphosphate kinase, magnesium complex of UTP
nucleoside diphosphate kinase OsNDPK1	Oryza sativa	adenosine 5'-diphosphatecosubstrate CTP	—	0.552	415	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK1, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK1	Oryza sativa	adenosine 5'-diphosphatecosubstrate GTP	—	0.707	69.9	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK1, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK1	Oryza sativa	adenosine 5'-diphosphatecosubstrate TTP	—	0.392	140	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK1, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK1	Oryza sativa	cytidine 5'-triphosphate	229	6.72	34.1	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK1, cytidine 5'-triphosphate
nucleoside diphosphate kinase OsNDPK1	Oryza sativa	guanosine 5'-triphosphate	49.4	1.69	29.2	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK1, guanosine 5'-triphosphate
nucleoside diphosphate kinase OsNDPK1	Oryza sativa	thymidine 5'-triphosphate	55	5.28	10.4	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK1, thymidine 5'-triphosphate
nucleoside diphosphate kinase OsNDPK2	Oryza sativa	adenosine 5'-diphosphatecosubstrate CTP	—	1.26	67.6	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK2, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK2	Oryza sativa	adenosine 5'-diphosphatecosubstrate GTP	—	0.138	210	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK2, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK2	Oryza sativa	adenosine 5'-diphosphatecosubstrate TTP	—	0.079	180	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK2, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK2	Oryza sativa	cytidine 5'-triphosphate	85.2	9.37	9.1	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK2, cytidine 5'-triphosphate
nucleoside diphosphate kinase OsNDPK2	Oryza sativa	guanosine 5'-triphosphate	27.7	0.45	61.6	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK2, guanosine 5'-triphosphate
nucleoside diphosphate kinase OsNDPK2	Oryza sativa	thymidine 5'-triphosphate	14.2	0.89	16	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK2, thymidine 5'-triphosphate
nucleoside diphosphate kinase OsNDPK3	Oryza sativa	adenosine 5'-diphosphatecosubstrate CTP	—	0.578	154	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK3, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK3	Oryza sativa	adenosine 5'-diphosphatecosubstrate GTP	—	0.125	143	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK3, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK3	Oryza sativa	adenosine 5'-diphosphatecosubstrate TTP	—	0.108	310	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK3, adenosine 5'-diphosphate
nucleoside diphosphate kinase OsNDPK3	Oryza sativa	cytidine 5'-triphosphate	89	5.28	16.9	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK3, cytidine 5'-triphosphate
nucleoside diphosphate kinase OsNDPK3	Oryza sativa	guanosine 5'-triphosphate	17.9	0.51	35.1	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK3, guanosine 5'-triphosphate
nucleoside diphosphate kinase OsNDPK3	Oryza sativa	thymidine 5'-triphosphate	33.5	1.34	25	pH 7.5, 25 °C	PMID 21897044	Open record: nucleoside diphosphate kinase OsNDPK3, thymidine 5'-triphosphate
nucleoside diphosphate kinase α-isoform	Rattus norvegicus	adenosine 5'-diphosphate	—	0.066	—		PMID 8142475	Open record: nucleoside diphosphate kinase α-isoform, adenosine 5'-diphosphate
nucleoside diphosphate kinase α-isoform	Rattus norvegicus	adenosine 5'-triphosphate	—	1.8	—		PMID 8142475	Open record: nucleoside diphosphate kinase α-isoform, adenosine 5'-triphosphate
nucleoside diphosphate kinase α-isoform	Rattus norvegicus	cytidine 5'-triphosphate	—	10	—		PMID 8142475	Open record: nucleoside diphosphate kinase α-isoform, cytidine 5'-triphosphate
nucleoside diphosphate kinase α-isoform	Rattus norvegicus	guanosine 5'-diphosphate	—	0.049	—		PMID 8142475	Open record: nucleoside diphosphate kinase α-isoform, guanosine 5'-diphosphate
nucleoside diphosphate kinase α-isoform	Rattus norvegicus	guanosine 5'-triphosphate	—	0.15	—		PMID 8142475	Open record: nucleoside diphosphate kinase α-isoform, guanosine 5'-triphosphate
nucleoside diphosphate kinase α-isoform	Rattus norvegicus	uridine 5'-triphosphate	—	27	—		PMID 8142475	Open record: nucleoside diphosphate kinase α-isoform, uridine 5'-triphosphate
nucleoside diphosphate kinase β-isoform	Rattus norvegicus	adenosine 5'-diphosphate	—	0.08	—		PMID 8142475	Open record: nucleoside diphosphate kinase β-isoform, adenosine 5'-diphosphate
nucleoside diphosphate kinase β-isoform	Rattus norvegicus	adenosine 5'-triphosphate	—	4.6	—		PMID 8142475	Open record: nucleoside diphosphate kinase β-isoform, adenosine 5'-triphosphate
nucleoside diphosphate kinase β-isoform	Rattus norvegicus	cytidine 5'-triphosphate	—	12	—		PMID 8142475	Open record: nucleoside diphosphate kinase β-isoform, cytidine 5'-triphosphate
nucleoside diphosphate kinase β-isoform	Rattus norvegicus	guanosine 5'-diphosphate	—	0.041	—		PMID 8142475	Open record: nucleoside diphosphate kinase β-isoform, guanosine 5'-diphosphate
nucleoside diphosphate kinase β-isoform	Rattus norvegicus	guanosine 5'-triphosphate	—	0.64	—		PMID 8142475	Open record: nucleoside diphosphate kinase β-isoform, guanosine 5'-triphosphate
nucleoside diphosphate kinase β-isoform	Rattus norvegicus	uridine 5'-triphosphate	—	16	—		PMID 8142475	Open record: nucleoside diphosphate kinase β-isoform, uridine 5'-triphosphate
nucleoside-diphosphate kinase	Aspergillus fumigatus	adenosine 5'-triphosphate	321	0.513	626	pH 8, 30 °C	PMID 33089641	Open record: nucleoside-diphosphate kinase, adenosine 5'-triphosphate
nucleoside-diphosphate kinase	Aspergillus fumigatus	cytidine 5'-triphosphate	53.1	1.32	40.2	pH 8, 30 °C	PMID 33089641	Open record: nucleoside-diphosphate kinase, cytidine 5'-triphosphate
nucleoside-diphosphate kinase	Aspergillus fumigatus	guanosine 5'-triphosphate	188	0.402	468	pH 8, 30 °C	PMID 33089641	Open record: nucleoside-diphosphate kinase, guanosine 5'-triphosphate
nucleoside-diphosphate kinase	Aspergillus fumigatus	inosine triphosphate	83.2	0.617	135	pH 8, 30 °C	PMID 33089641	Open record: nucleoside-diphosphate kinase, inosine triphosphate
nucleoside-diphosphate kinase	Aspergillus fumigatus	thymidine 5'-triphosphate	178	2.23	79.8	pH 8, 30 °C	PMID 33089641	Open record: nucleoside-diphosphate kinase, thymidine 5'-triphosphate
nucleoside-diphosphate kinase	Aspergillus fumigatus	uridine 5'-triphosphate	140	1.35	104	pH 8, 30 °C	PMID 33089641	Open record: nucleoside-diphosphate kinase, uridine 5'-triphosphate
UMP/CMP kinase 1 (UMP/CMPK1)	Homo sapiens	2′-deoxycytidine-5′-monophosphate	13.4	0.11	122		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1), 2′-deoxycytidine-5′-monophosphate
UMP/CMP kinase 1 (UMP/CMPK1)	Homo sapiens	2′-deoxyuridine-5′-monophosphate	5.8	1.034	5.61		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1), 2′-deoxyuridine-5′-monophosphate
UMP/CMP kinase 1 (UMP/CMPK1)	Homo sapiens	5azaCDV	0.47	2.08	0.226		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1), 5azaCDV
UMP/CMP kinase 1 (UMP/CMPK1)	Homo sapiens	arabinocytidine-5′-monophosphate	130	0.315	410		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1), arabinocytidine-5′-monophosphate
UMP/CMP kinase 1 (UMP/CMPK1)	Homo sapiens	cidofovir	0.09	2.3	0.04		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1), cidofovir
UMP/CMP kinase 1 (UMP/CMPK1)	Homo sapiens	cytidine-5′-monophosphate	125	0.02	6.25 × 10³		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1), cytidine-5′-monophosphate
UMP/CMP kinase 1 (UMP/CMPK1)	Homo sapiens	uridine-5′-monophosphate	188	0.1	1.88 × 10³		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1), uridine-5′-monophosphate
UMP/CMP kinase 1 (UMP/CMPK1)variant P64T	Homo sapiens	2′-deoxycytidine-5′-monophosphate	0.036	0.97	0.037		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1) variant P64T, 2′-deoxycytidine-5′-monophosphate
UMP/CMP kinase 1 (UMP/CMPK1)variant P64T	Homo sapiens	arabinocytidine-5′-monophosphate	0.019	0.327	0.058		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1) variant P64T, arabinocytidine-5′-monophosphate
UMP/CMP kinase 1 (UMP/CMPK1)variant P64T	Homo sapiens	cytidine-5′-monophosphate	0.31	0.123	2.52		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1) variant P64T, cytidine-5′-monophosphate
UMP/CMP kinase 1 (UMP/CMPK1)variant P64T	Homo sapiens	uridine-5′-monophosphate	0.35	0.25	1.4		PMID 26824416	Open record: UMP/CMP kinase 1 (UMP/CMPK1) variant P64T, uridine-5′-monophosphate