CatLogenzyme kinetics catalog

EC 2.7.4.8: guanylate kinase

TransferasesOpen in Browse

CatLog read 8 records for EC 2.7.4.8 from 1 paper, for 1 organism. Names in these papers: guanylate kinase (hGMPK).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 35 records for EC 2.7.4.8 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.4.8 in Browse.

Papers

PaperOrganismsRecords
Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancerHomo sapiens8

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
guanylate kinase (hGMPK)Homo sapiensguanosine 5'-monophosphate58.50.02072.8 × 10³pH 7.5, 25 °CPMID 31201273Open
guanylate kinase (hGMPK)variant G3AHomo sapiensguanosine 5'-monophosphate184.40.07832.4 × 10³pH 7.5, 25 °CPMID 31201273Open
guanylate kinase (hGMPK)variant R116QHomo sapiensguanosine 5'-monophosphate1270.05432.3 × 10³pH 7.5, 25 °CPMID 31201273Open
guanylate kinase (hGMPK)variant R96HHomo sapiensguanosine 5'-monophosphate100.60.02963.4 × 10³pH 7.5, 25 °CPMID 31201273Open
guanylate kinase (hGMPK)variant S121FHomo sapiensguanosine 5'-monophosphate101.40.04862.1 × 10³pH 7.5, 25 °CPMID 31201273Open
guanylate kinase (hGMPK)variant S186YHomo sapiensguanosine 5'-monophosphate96.50.03682.6 × 10³pH 7.5, 25 °CPMID 31201273Open
guanylate kinase (hGMPK)variant S2LHomo sapiensguanosine 5'-monophosphate77.70.03152.5 × 10³pH 7.5, 25 °CPMID 31201273Open
guanylate kinase (hGMPK)variant V91MHomo sapiensguanosine 5'-monophosphate132.20.05472.4 × 10³pH 7.5, 25 °CPMID 31201273Open