EC 2.7.7.24: glucose-1-phosphate thymidylyltransferase

TransferasesOpen in Browse

CatLog read 42 records for EC 2.7.7.24 from 6 papers, for 6 organisms. Names in these papers: glucose-1-phosphate thymidylyltransferase RmlA, Cps2L (glucose-1-phosphate thymidylyltransferase), ST0452 protein (sugar-1-phosphate nucleotidylyltransferase), glucose-1-phosphate thymidylyltransferase (RmlA) and 2 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 19 records for EC 2.7.7.24 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.7.24 in Browse.

Papers

Papers with records for EC 2.7.7.24
Paper	Organisms	Records
Enhancing the latent nucleotide triphosphate flexibility of the glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	14
Kinetic evaluation of glucose 1-phosphate analogues with a thymidylyltransferase using a continuous coupled enzyme assay	Streptococcus pneumoniae	10
Increasing the Thermostable Sugar-1-Phosphate Nucleotidylyltransferase Activities of the Archaeal ST0452 Protein through Site Saturation Mutagenesis of the 97th Amino Acid Position	Sulfolobus tokodaii	8
Homologs of the Rml enzymes from Salmonella enterica are responsible for dTDP-beta-L-rhamnose biosynthesis in the gram-positive thermophile Aneurinibacillus thermoaerophilus DSM 10155	Aneurinibacillus thermoaerophilus	4
Identification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegans	Caenorhabditis elegans	4
Identification of two highly promiscuous thermostable sugar nucleotidylyltransferases for glycorandomization	Neisseria gonorrhoeae	2

Records

Records for EC 2.7.7.24 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	(alpha-D-glucopyranosyl)methylphosphonic acidcoupled assay: inosine 1 mM; PNP 1 µM; cosubstrate dTTP	0.55	0.18	31	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), (alpha-D-glucopyranosyl)methylphosphonic acid
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	(alpha-D-glucopyranosyl)methylphosphonic acidcoupled assay: inosine 1 mM; PNP 1 µM; cosubstrate UTP	0.01	0.38	0.28	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), (alpha-D-glucopyranosyl)methylphosphonic acid
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	(alpha-D-glucopyranosyl)methylphosphonic acidrates fit to a competitive substrate model (Fig. 2e)	—	—	80	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), (alpha-D-glucopyranosyl)methylphosphonic acid
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	2-amino-2-deoxy-alpha-D-glucopyranosyl phosphatedTTP; cosubstrate dTTP	4.5	0.69	6.5	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), 2-amino-2-deoxy-alpha-D-glucopyranosyl phosphate
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	2-amino-2-deoxy-alpha-D-glucopyranosyl phosphateUTP; cosubstrate UTP	0.1	0.7	0.15	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), 2-amino-2-deoxy-alpha-D-glucopyranosyl phosphate
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	3-amino-3-deoxy-alpha-D-glucopyranosyl phosphate	0.08	1.1	0.072	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), 3-amino-3-deoxy-alpha-D-glucopyranosyl phosphate
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	3-azido-3-deoxy-alpha-D-glucopyranosyl phosphate	3 × 10⁻⁴	1.1	2.7 × 10⁻⁴	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), 3-azido-3-deoxy-alpha-D-glucopyranosyl phosphate
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	alpha-D-glucose 1-phosphatecoupled assay: inosine 1 mM; PNP 1 µM; cosubstrate dTTP	24	0.083	280	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), alpha-D-glucose 1-phosphate
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	alpha-D-glucose 1-phosphatecoupled assay: inosine 1 mM; PNP 1 µM; cosubstrate UTP	0.016	0.16	9.6	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), alpha-D-glucose 1-phosphate
Cps2L (glucose-1-phosphate thymidylyltransferase)	Streptococcus pneumoniae	alpha-D-glucose 1-phosphaterates fit to a competitive substrate model (Fig. 2e)	—	—	830	pH 7.5	PMID 25408103	Open record: Cps2L (glucose-1-phosphate thymidylyltransferase), alpha-D-glucose 1-phosphate
glucose-1-phosphate thymidylyltransferase (NGGT)	Neisseria gonorrhoeae	glucose-1-phosphate	1.02	0.252	4.05 calc.	pH 7.6	PMID 29806742	Open record: glucose-1-phosphate thymidylyltransferase (NGGT), glucose-1-phosphate
glucose-1-phosphate thymidylyltransferase (NGGT)	Neisseria gonorrhoeae	uridine 5'-triphosphate	1.9	0.2725	7.0 calc.	pH 7.6, 37 °C	PMID 29806742	Open record: glucose-1-phosphate thymidylyltransferase (NGGT), uridine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase (RmlA)	Aneurinibacillus thermoaerophilus	alpha-D-glucose 1-phosphate	13	0.2	65 calc.	25 °C	PMID 12147463	Open record: glucose-1-phosphate thymidylyltransferase (RmlA), alpha-D-glucose 1-phosphate
glucose-1-phosphate thymidylyltransferase (RmlA)	Aneurinibacillus thermoaerophilus	diphosphate	10	0.055	180 calc.	25 °C	PMID 12147463	Open record: glucose-1-phosphate thymidylyltransferase (RmlA), diphosphate
glucose-1-phosphate thymidylyltransferase (RmlA)	Aneurinibacillus thermoaerophilus	dTDP-alpha-D-glucose	15	0.13	120 calc.	25 °C	PMID 12147463	Open record: glucose-1-phosphate thymidylyltransferase (RmlA), dTDP-alpha-D-glucose
glucose-1-phosphate thymidylyltransferase (RmlA)	Aneurinibacillus thermoaerophilus	thymidine 5'-triphosphate	8.9	0.031	290 calc.	25 °C	PMID 12147463	Open record: glucose-1-phosphate thymidylyltransferase (RmlA), thymidine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	2'-deoxyadenosine 5'-triphosphate	1.88	7.8	0.242	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA, 2'-deoxyadenosine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	2'-deoxycytidine 5'-triphosphate	1.22	10.5	0.117	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA, 2'-deoxycytidine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	2'-deoxyguanosine 5'-triphosphate	2.12	3.7	0.57	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA, 2'-deoxyguanosine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	2'-deoxythymidine 5'-triphosphate	30.8	0.29	105	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA, 2'-deoxythymidine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	adenosine 5'-triphosphate	0.0553	9	0.0065	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA, adenosine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	cytidine 5'-triphosphate	0.098	13.7	0.0072	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA, cytidine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	guanosine 5'-triphosphate	0.14	8.5	0.0165	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA, guanosine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlA	Salmonella enterica serovar Typhimurium	uridine 5'-triphosphate	41	4.6	8.8	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA, uridine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlAvariant Q83D	Salmonella enterica serovar Typhimurium	2'-deoxyguanosine 5'-triphosphate	5	11.5	0.43	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA variant Q83D, 2'-deoxyguanosine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlAvariant Q83D	Salmonella enterica serovar Typhimurium	2'-deoxythymidine 5'-triphosphate	3.62	6.2	0.58	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA variant Q83D, 2'-deoxythymidine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlAvariant Q83D	Salmonella enterica serovar Typhimurium	guanosine 5'-triphosphate	0.213	1.3	0.17	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA variant Q83D, guanosine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlAvariant Q83S	Salmonella enterica serovar Typhimurium	2'-deoxyadenosine 5'-triphosphate	5.3	1.1	4.7	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA variant Q83S, 2'-deoxyadenosine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlAvariant Q83S	Salmonella enterica serovar Typhimurium	2'-deoxythymidine 5'-triphosphate	6.3	2.4	2.7	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA variant Q83S, 2'-deoxythymidine 5'-triphosphate
glucose-1-phosphate thymidylyltransferase RmlAvariant Q83S	Salmonella enterica serovar Typhimurium	adenosine 5'-triphosphate	0.48	3.4	0.138	pH 8, 37 °C	PMID 17434871	Open record: glucose-1-phosphate thymidylyltransferase RmlA variant Q83S, adenosine 5'-triphosphate
RML-1	Caenorhabditis elegans	2'-deoxythymidine 5'-triphosphate	28.2	0.02422	1.16 × 10³	pH 7.5, 25 °C	PMID 27009306	Open record: RML-1, 2'-deoxythymidine 5'-triphosphate
RML-1	Caenorhabditis elegans	alpha-D-glucose 1-phosphateGlc-1-P varied with UTP fixed at 1 mM; cosubstrate UTP	23.24	0.03224	720	pH 7.5, 25 °C	PMID 27009306	Open record: RML-1, alpha-D-glucose 1-phosphate
RML-1	Caenorhabditis elegans	alpha-D-glucose 1-phosphateGlc-1-P varied with dTTP fixed at 1 mM; cosubstrate dTTP	23.58	0.04988	470	pH 7.5, 25 °C	PMID 27009306	Open record: RML-1, alpha-D-glucose 1-phosphate
RML-1	Caenorhabditis elegans	uridine 5'-triphosphate	21.92	0.00947	2.31 × 10³	pH 7.5, 25 °C	PMID 27009306	Open record: RML-1, uridine 5'-triphosphate
ST0452 protein (sugar-1-phosphate nucleotidylyltransferase)	Sulfolobus tokodaii	glucose-1-phosphate	2.97	1.23	2.41	pH 7.5, 80 °C	PMID 27864169	Open record: ST0452 protein (sugar-1-phosphate nucleotidylyltransferase), glucose-1-phosphate
ST0452 protein (sugar-1-phosphate nucleotidylyltransferase)	Sulfolobus tokodaii	N-acetyl-D-glucosamine-1-phosphate	9.97	0.068	146.6	pH 7.5, 80 °C	PMID 27864169	Open record: ST0452 protein (sugar-1-phosphate nucleotidylyltransferase), N-acetyl-D-glucosamine-1-phosphate
ST0452 protein (sugar-1-phosphate nucleotidylyltransferase)variant Y97M	Sulfolobus tokodaii	glucose-1-phosphate	14.97	1.74	8.6	pH 7.5, 80 °C	PMID 27864169	Open record: ST0452 protein (sugar-1-phosphate nucleotidylyltransferase) variant Y97M, glucose-1-phosphate
ST0452 protein (sugar-1-phosphate nucleotidylyltransferase)variant Y97M	Sulfolobus tokodaii	N-acetyl-D-glucosamine-1-phosphate	10.9	0.097	112.4	pH 7.5, 80 °C	PMID 27864169	Open record: ST0452 protein (sugar-1-phosphate nucleotidylyltransferase) variant Y97M, N-acetyl-D-glucosamine-1-phosphate
ST0452 protein (sugar-1-phosphate nucleotidylyltransferase)variant Y97N	Sulfolobus tokodaii	glucose-1-phosphate	38.15	2.53	15.08	pH 7.5, 80 °C	PMID 27864169	Open record: ST0452 protein (sugar-1-phosphate nucleotidylyltransferase) variant Y97N, glucose-1-phosphate
ST0452 protein (sugar-1-phosphate nucleotidylyltransferase)variant Y97N	Sulfolobus tokodaii	N-acetyl-D-glucosamine-1-phosphate	49.75	0.147	338.4	pH 7.5, 80 °C	PMID 27864169	Open record: ST0452 protein (sugar-1-phosphate nucleotidylyltransferase) variant Y97N, N-acetyl-D-glucosamine-1-phosphate
ST0452 protein (sugar-1-phosphate nucleotidylyltransferase)variant Y97V	Sulfolobus tokodaii	glucose-1-phosphate	2.08	3.28	0.63	pH 7.5, 80 °C	PMID 27864169	Open record: ST0452 protein (sugar-1-phosphate nucleotidylyltransferase) variant Y97V, glucose-1-phosphate
ST0452 protein (sugar-1-phosphate nucleotidylyltransferase)variant Y97V	Sulfolobus tokodaii	N-acetyl-D-glucosamine-1-phosphate	48.95	0.861	56.9	pH 7.5, 80 °C	PMID 27864169	Open record: ST0452 protein (sugar-1-phosphate nucleotidylyltransferase) variant Y97V, N-acetyl-D-glucosamine-1-phosphate