CatLogenzyme kinetics catalog

EC 2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

TransferasesOpen in Browse

CatLog read 51 records for EC 2.7.7.60 from 2 papers, for 2 organisms. Names in these papers: 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD), 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (BsIspD), 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (EcIspD).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 20 records for EC 2.7.7.60 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.7.7.60 in Browse.

Papers

PaperOrganismsRecords
Kinetic analysis of Escherichia coli 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase, wild type and mutants, reveals roles of active site amino acidsEscherichia coli47
A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilisBacillus subtilis, Escherichia coli4

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)Escherichia coli2-C-methyl-D-erythritol 4-phosphate—0.37—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)Escherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat25.9——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)Escherichia coli2-C-methyl-D-erythritol 4-phosphate48.4——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)Escherichia coli2-C-methyl-D-erythritol 4-phosphate——13123 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)Escherichia colicytidine 5'-triphosphate54.10.767123 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant D106EEscherichia coli2-C-methyl-D-erythritol 4-phosphate—15.5—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant D106EEscherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat0.54——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant D106EEscherichia coli2-C-methyl-D-erythritol 4-phosphate0.9——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant D106EEscherichia coli2-C-methyl-D-erythritol 4-phosphate——0.0623 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant D106EEscherichia colicytidine 5'-triphosphate0.931.40.6623 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant K27SEscherichia coli2-C-methyl-D-erythritol 4-phosphate—3—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant K27SEscherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat0.04——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant K27SEscherichia coli2-C-methyl-D-erythritol 4-phosphate0.75——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant K27SEscherichia coli2-C-methyl-D-erythritol 4-phosphate——0.2523 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant K27SEscherichia colicytidine 5'-triphosphate2.051.10.523 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R109AEscherichia coli2-C-methyl-D-erythritol 4-phosphate—131.5—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R109AEscherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat0.27——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R109AEscherichia coli2-C-methyl-D-erythritol 4-phosphate0.4——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R109AEscherichia coli2-C-methyl-D-erythritol 4-phosphate——0.00323 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R109AEscherichia colicytidine 5'-triphosphate0.2630.123 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R109AEscherichia colicytidine 5'-triphosphateapparent kcat0.17——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19AEscherichia coli2-C-methyl-D-erythritol 4-phosphate—2.98—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19AEscherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat19.6——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19AEscherichia coli2-C-methyl-D-erythritol 4-phosphate36.8——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19AEscherichia coli2-C-methyl-D-erythritol 4-phosphate——1223 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19AEscherichia colicytidine 5'-triphosphate27.52.81023 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19KEscherichia coli2-C-methyl-D-erythritol 4-phosphate—0.74—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19KEscherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat23.2——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19KEscherichia coli2-C-methyl-D-erythritol 4-phosphate47.2——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19KEscherichia coli2-C-methyl-D-erythritol 4-phosphate——6423 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R19KEscherichia colicytidine 5'-triphosphate46.40.8554.623 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20AEscherichia coli2-C-methyl-D-erythritol 4-phosphate—3.28—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20AEscherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat22.6——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20AEscherichia coli2-C-methyl-D-erythritol 4-phosphate52.7——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20AEscherichia coli2-C-methyl-D-erythritol 4-phosphate——1623 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20AEscherichia colicytidine 5'-triphosphate40.26.6623 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20KEscherichia coli2-C-methyl-D-erythritol 4-phosphate—0.31—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20KEscherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat6.7——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20KEscherichia coli2-C-methyl-D-erythritol 4-phosphate21.4——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20KEscherichia coli2-C-methyl-D-erythritol 4-phosphate——6923 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant R20KEscherichia colicytidine 5'-triphosphate53.63.714.523 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant T140VEscherichia coli2-C-methyl-D-erythritol 4-phosphate—49—23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant T140VEscherichia coli2-C-methyl-D-erythritol 4-phosphateapparent kcat2.7——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant T140VEscherichia coli2-C-methyl-D-erythritol 4-phosphate4——23 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant T140VEscherichia coli2-C-methyl-D-erythritol 4-phosphate——0.0823 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant T140VEscherichia colicytidine 5'-triphosphate1.820.923 °CPMID 15379557Open
2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (YgbP, IspD)variant T140VEscherichia colicytidine 5'-triphosphateapparent kcat1.21——23 °CPMID 15379557Open
2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (BsIspD)Bacillus subtilis2-C-methyl-D-erythritol 4-phosphate36.350.1248291.3pH 8, 30 °CPMID 27821871Open
2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (BsIspD)Bacillus subtiliscytidine 5'-triphosphate71.240.1328536.5pH 8, 30 °CPMID 27821871Open
2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (EcIspD)Escherichia coli2-C-methyl-D-erythritol 4-phosphate38.450.2915131.9pH 8, 30 °CPMID 27821871Open
2-C-methyl-D-erythritol-4-phosphate cytidyltransferase (EcIspD)Escherichia colicytidine 5'-triphosphate79.500.2309344.3pH 8, 30 °CPMID 27821871Open