CatLogenzyme kinetics catalog

EC 2.8.2.4: estrone sulfotransferase

TransferasesOpen in Browse

CatLog read 53 records for EC 2.8.2.4 from 6 papers, for 2 organisms. Names in these papers: estrogen sulfotransferase (EST), estrogen sulfotransferase (humSULT1E1), SULT1E1, hSULT1E1.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 32 records for EC 2.8.2.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.8.2.4 in Browse.

Papers

PaperOrganismsRecords
The sulfuryl transfer mechanism. Crystal structure of a vanadate complex of estrogen sulfotransferase and mutational analysisMus musculus19
Site-directed mutagenesis of the substrate-binding cleft of human estrogen sulfotransferaseHomo sapiens18
Regioselective monosulfation and disulfation of the phytoestrogens daidzein and genistein by human liver sulfotransferasesHomo sapiens8
Variable sulfation of dietary polyphenols by recombinant human sulfotransferase (SULT) 1A1 genetic variants and SULT1E1Homo sapiens5
24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver x receptor…Homo sapiens2
Inhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferasesHomo sapiens1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
estrogen sulfotransferase (EST)Mus musculusadenosine 3'-phosphate 5'-phosphosulfate—3 × 10⁻⁴—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)Mus musculusestradiol0.02351.75 × 10⁻⁵1.3 × 10³pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant H108KMus musculusestradiol2 × 10⁻⁴5.43 × 10⁻⁵4.2pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant K106AMus musculusadenosine 3'-phosphate 5'-phosphosulfate—7.5 × 10⁻⁴—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant K106AMus musculusestradiol3 × 10⁻⁴1.192 × 10⁻⁴0.44pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant K106RMus musculusadenosine 3'-phosphate 5'-phosphosulfate—5.4 × 10⁻⁴—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant K106RMus musculusestradiol2 × 10⁻⁴5.8 × 10⁻⁵3.8pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant K106SMus musculusadenosine 3'-phosphate 5'-phosphosulfate—8 × 10⁻⁴—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant K106SMus musculusestradiol3 × 10⁻⁴8.85 × 10⁻⁵2.3pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant K48RMus musculusadenosine 3'-phosphate 5'-phosphosulfate—3.5 × 10⁻⁴—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant K48RMus musculusestradiol0.00561.8 × 10⁻⁵310pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant T45VMus musculusadenosine 3'-phosphate 5'-phosphosulfate—3.5 × 10⁻⁴—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant T45VMus musculusestradiol0.00422.14 × 10⁻⁵200pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant T51VMus musculusadenosine 3'-phosphate 5'-phosphosulfate—0.0023—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant T51VMus musculusestradiol0.00452.73 × 10⁻⁵160pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant T52VMus musculusadenosine 3'-phosphate 5'-phosphosulfate—7 × 10⁻⁴—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant T52VMus musculusestradiol0.00116.45 × 10⁻⁵17pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant Y240FMus musculusadenosine 3'-phosphate 5'-phosphosulfate—9.5 × 10⁻⁴—pH 8PMID 9765259Open
estrogen sulfotransferase (EST)variant Y240FMus musculusestradiol0.02182.33 × 10⁻⁵940pH 8PMID 9765259Open
estrogen sulfotransferase (humSULT1E1)Homo sapiens17beta-estradiol—3 × 10⁻⁴—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)Homo sapiens3'-phosphoadenosine 5'-phosphosulfate—4.6 × 10⁻⁴—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)Homo sapiens4-nitrophenol—0.0766—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)Homo sapiensdehydroepiandrosterone—2 × 10⁻⁴—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)Homo sapiensDopamine—32.22—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)Homo sapiensEstrone—2 × 10⁻⁴—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant K85AHomo sapiens17beta-estradiol—1 × 10⁻⁴—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant K85AHomo sapiens3'-phosphoadenosine 5'-phosphosulfate—6.9 × 10⁻⁴—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant K85AHomo sapiens4-nitrophenol—0.6248—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant K85AHomo sapiensdehydroepiandrosterone—5 × 10⁻⁵—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant K85AHomo sapiensDopamine—79.35—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant K85AHomo sapiensEstrone—1 × 10⁻⁴—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant V145EHomo sapiens17beta-estradiol—0.0082—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant V145EHomo sapiens3'-phosphoadenosine 5'-phosphosulfate—0.01318—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant V145EHomo sapiens4-nitrophenol—0.9372—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant V145EHomo sapiensdehydroepiandrosterone—0.0607—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant V145EHomo sapiensDopamine—0.2407—pH 7, 37 °CPMID 11006110Open
estrogen sulfotransferase (humSULT1E1)variant V145EHomo sapiensEstrone—0.0036—pH 7, 37 °CPMID 11006110Open
hSULT1E1Homo sapiensβ-Oestradiol—3.3 × 10⁻⁴—pH 7.4, 37 °CPMID 19548878Open
SULT1E1Homo sapiens(-)-epicatechin—0.9618—pH 6.5, 37 °CPMID 17293380Open
SULT1E1Homo sapiens24(S)-hydroxycholesterol24-OHChol-3-monosulfate—9 × 10⁻⁴—pH 7.4, 37 °CPMID 19589875Open
SULT1E1Homo sapiens24(S)-hydroxycholesterol24-OHChol-3,24-disulfate—0.0049—pH 7.4, 37 °CPMID 19589875Open
SULT1E1Homo sapiens5,7,4'-trihydroxyisoflavone7-sulfation of genistein (formation of GS 7-sulfate)0.12080.0027944.7pH 7.4PMID 15499189Open
SULT1E1Homo sapiens5,7,4'-trihydroxyisoflavone4'-sulfation of genistein (formation of GS 4'-sulfate)0.12420.0029442.2pH 7.4PMID 15499189Open
SULT1E1Homo sapiens7,4'-dihydroxyisoflavone7-sulfation of daidzein (formation of DZ 7-sulfate)0.09520.0025736.93pH 7.4PMID 15499189Open
SULT1E1Homo sapiens7,4'-dihydroxyisoflavone4'-sulfation of daidzein (formation of DZ 4'-sulfate)0.10650.0032432.87pH 7.4PMID 15499189Open
SULT1E1Homo sapiensapigenin—0.0053—pH 6.5, 37 °CPMID 17293380Open
SULT1E1Homo sapienschrysin—0.0045—pH 6.5, 37 °CPMID 17293380Open
SULT1E1Homo sapiensdaidzein 4'-sulfate0.0630.05161.227pH 7.4PMID 15499189Open
SULT1E1Homo sapiensdaidzein 7-sulfate0.0770.04351.762pH 7.4PMID 15499189Open
SULT1E1Homo sapiensgenistein 4'-sulfate0.0350.02661.315pH 7.4PMID 15499189Open
SULT1E1Homo sapiensgenistein 7-sulfate0.060.032pH 7.4PMID 15499189Open
SULT1E1Homo sapiensquercetin—0.002—pH 6.5, 37 °CPMID 17293380Open
SULT1E1Homo sapiensresveratrol—0.00688—pH 6.5, 37 °CPMID 17293380Open