EC 3.1.1.79: hormone-sensitive lipase

HydrolasesOpen in Browse

CatLog read 123 records for EC 3.1.1.79 from 4 papers, for 3 organisms. Names in these papers: MmLipN, arylacetamide deacetylase (AADAC), hormone-sensitive lipase (HSL), ABHD2 (alpha/beta hydrolase domain-containing protein 2; TAG lipase and ester hydrolase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 83 records for EC 3.1.1.79 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.1.79 in Browse.

Papers

Papers with records for EC 3.1.1.79
Paper	Organisms	Records
Sequence and Structural Motifs Controlling the Broad Substrate Specificity of the Mycobacterial Hormone-Sensitive Lipase LipN	Mycobacterium marinum	89
Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse	Homo sapiens, Mus musculus	22
Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases	Homo sapiens	9
Molecular characterization of human ABHD2 as TAG lipase and ester hydrolase	Homo sapiens	3

Records

Records for EC 3.1.1.79 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
ABHD2 (alpha/beta hydrolase domain-containing protein 2; TAG lipase and ester hydrolase)	Homo sapiens	p-nitrophenyl acetate	—	12.4	0.01123		PMID 27247428	Open record: ABHD2 (alpha/beta hydrolase domain-containing protein 2; TAG lipase and ester hydrolase), p-nitrophenyl acetate
ABHD2 (alpha/beta hydrolase domain-containing protein 2; TAG lipase and ester hydrolase)	Homo sapiens	p-nitrophenyl butyrate	—	11.76	0.01633		PMID 27247428	Open record: ABHD2 (alpha/beta hydrolase domain-containing protein 2; TAG lipase and ester hydrolase), p-nitrophenyl butyrate
ABHD2 (alpha/beta hydrolase domain-containing protein 2; TAG lipase and ester hydrolase)	Homo sapiens	p-nitrophenyl palmitate	—	17.66	0.00372		PMID 27247428	Open record: ABHD2 (alpha/beta hydrolase domain-containing protein 2; TAG lipase and ester hydrolase), p-nitrophenyl palmitate
arylacetamide deacetylase (AADAC)	Homo sapiens	flutamideSf21 cell homogenate expressing AADAC 0.4 mg/ml	—	0.6	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Homo sapiens	flutamidemicrosomal protein 0.4 mg/ml; flutamide 0.025-0.75 mM	—	1.1	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Homo sapiens	flutamidemicrosomal protein 0.4 mg/ml; flutamide 0.005-0.75 mM	—	0.2	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Homo sapiens	flutamidemicrosomal protein 0.4 mg/ml; flutamide 0.005-0.75 mM	—	4.7	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Homo sapiens	flutamidemicrosomal protein 0.4 mg/ml; flutamide 0.025-0.75 mM	—	2.1	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Homo sapiens	phenacetinSf21 cell homogenate expressing AADAC; total cell homogenate	—	1.8	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Homo sapiens	phenacetinmicrosomal protein; crude microsomal fraction	—	3.3	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Homo sapiens	phenacetinmicrosomal protein; crude microsomal fraction	—	2.5	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Homo sapiens	phenacetinmicrosomal protein; crude microsomal fraction	—	2.3	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Homo sapiens	phenacetinmicrosomal protein; crude microsomal fraction	—	7.4	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Homo sapiens	rifampicinSf21 cell homogenate expressing AADAC; total cell homogenate	—	0.2	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), rifampicin
arylacetamide deacetylase (AADAC)	Homo sapiens	rifampicinmicrosomal protein; crude microsomal fraction	—	0.4	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), rifampicin
arylacetamide deacetylase (AADAC)	Homo sapiens	rifampicinmicrosomal protein; crude microsomal fraction	—	0.3	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), rifampicin
arylacetamide deacetylase (AADAC)	Mus musculus	flutamideSf21 cell homogenate expressing AADAC; total cell homogenate	—	3.5	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Mus musculus	flutamidemicrosomal protein; crude microsomal fraction	—	7.3	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Mus musculus	flutamidemicrosomal protein; crude microsomal fraction	—	0.5	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Mus musculus	flutamidemicrosomal protein; crude microsomal fraction	—	0.8	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), flutamide
arylacetamide deacetylase (AADAC)	Mus musculus	phenacetinSf21 cell homogenate expressing AADAC 0.2; not purified	—	1.6	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Mus musculus	phenacetinmicrosomal protein 0.4; crude microsomal fraction	—	9.8	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Mus musculus	phenacetinmicrosomal protein 0.4; crude microsomal fraction	—	11.2	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Mus musculus	phenacetinmicrosomal protein 0.4; crude microsomal fraction	—	7.1	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
arylacetamide deacetylase (AADAC)	Mus musculus	phenacetinmicrosomal protein 0.4; crude microsomal fraction	—	2.9	—	pH 7.4	PMID 22207054	Open record: arylacetamide deacetylase (AADAC), phenacetin
hormone-sensitive lipase (HSL)	Homo sapiens	4-nitrophenyl butanoate	190	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), 4-nitrophenyl butanoate
hormone-sensitive lipase (HSL)	Homo sapiens	ethenyl acetate	140	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), ethenyl acetate
hormone-sensitive lipase (HSL)	Homo sapiens	ethenyl butanoate	210	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), ethenyl butanoate
hormone-sensitive lipase (HSL)	Homo sapiens	ethenyl dodecanoate	31	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), ethenyl dodecanoate
hormone-sensitive lipase (HSL)	Homo sapiens	ethenyl propanoate	105	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), ethenyl propanoate
hormone-sensitive lipase (HSL)	Homo sapiens	glycerol tributanoate	18	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), glycerol tributanoate
hormone-sensitive lipase (HSL)	Homo sapiens	glycerol trioctanoate	6	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), glycerol trioctanoate
hormone-sensitive lipase (HSL)	Homo sapiens	glycerol tripropanoate	7	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), glycerol tripropanoate
hormone-sensitive lipase (HSL)	Homo sapiens	Olive oil	6	—	—	pH 7.5, 25 °C	PMID 16325466	Open record: hormone-sensitive lipase (HSL), Olive oil
MmLipN	Mycobacterium marinum	Fluorescein bis((((1-(2-pyridinyl))cyclopropyl)carboxymethyl ether)	2.6 × 10⁻⁵	4.9 × 10⁻⁵	0.53	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis((((1-(2-pyridinyl))cyclopropyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(((1-cyano)cyclopropyl)carboxymethyl ether)	0.0012	0.0017	0.67	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(((1-cyano)cyclopropyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(((1-hydroxy)cyclopropyl)carboxymethyl ether))	0.0029	4 × 10⁻⁴	7.4	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(((1-hydroxy)cyclopropyl)carboxymethyl ether))
MmLipN	Mycobacterium marinum	Fluorescein bis(((1-methanesulfonyl)cyclopropyl)carboxymethyl ether)	1.4 × 10⁻⁵	8.4 × 10⁻⁵	0.17	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(((1-methanesulfonyl)cyclopropyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(((1-phenyl)cyclopropyl)carboxymethyl ether)	5.8 × 10⁻⁵	0.013	0.0044	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(((1-phenyl)cyclopropyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(((1-trifluoromethyl)cyclopropyl)carboxymethyl ether)	3.7 × 10⁻⁵	3.7 × 10⁻⁴	0.098	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(((1-trifluoromethyl)cyclopropyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(((2,2-dichloro-1-methyl)cyclopropyl)carboxymethyl ether)	1.1 × 10⁻⁵	8.7 × 10⁻⁴	0.012	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(((2,2-dichloro-1-methyl)cyclopropyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(((2,2-dimethyl)cyclopropyl)carboxymethyl ether)	0.0011	0.0017	0.66	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(((2,2-dimethyl)cyclopropyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis((2-methyl)propionyloxymethyl ether)	0.017	0.0095	1.8	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis((2-methyl)propionyloxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis((3-methyl)propargyloxymethyl ether)	0.0061	0.0018	3.3	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis((3-methyl)propargyloxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.003	3.3 × 10⁻⁵	91	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(3-(2-methoxyethoxy)propionyloxymethyl ether)	5 × 10⁻⁴	0.021	0.026	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(3-(2-methoxyethoxy)propionyloxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(crotonyloxymethyl ether)	0.0029	5.1 × 10⁻⁵	5.7	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(crotonyloxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(cyanoacetyloxymethyl ether)	0.015	0.0031	4.9	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(cyanoacetyloxymethyl ether)
MmLipN	Mycobacterium marinum	Fluorescein bis(cyclopropyl)carboxymethyl ether)	9 × 10⁻⁴	3.7 × 10⁻⁴	2.6	pH 7.4	PMID 37065048	Open record: MmLipN, Fluorescein bis(cyclopropyl)carboxymethyl ether)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.1	2.2 × 10⁻⁴	460	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 12 (a/b unsaturated ester)	0.02	0.0034	6.1	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 12 (a/b unsaturated ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 13 (a/b unsaturated ester)	0.0093	3.2 × 10⁻⁵	29	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 13 (a/b unsaturated ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 16 (cycloalkyl ester)	0.025	0.003	8.3	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 16 (cycloalkyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 17 (cycloalkyl ester; cyclopentyl ester)	0.0012	0.0339	0.029	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 17 (cycloalkyl ester; cyclopentyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 18 (cycloalkyl ester)	7 × 10⁻⁴	0.029	0.025	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 18 (cycloalkyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 19 (cycloalkyl ester; furan ester)	0.003	8.4 × 10⁻⁴	3.5	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 19 (cycloalkyl ester; furan ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 2 (alkyl ester; propionyl ester)	0.18	0.0042	42	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 2 (alkyl ester; propionyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 21 (cycloalkyl ester)	3 × 10⁻⁴	0.0012	0.31	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 21 (cycloalkyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 22 (tertiary ester; pivalic tertiary ester)	2.4 × 10⁻⁵	7.1 × 10⁻⁴	0.034	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 22 (tertiary ester; pivalic tertiary ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 3 (alkyl ester; butyl ester)	0.062	0.0062	10	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 3 (alkyl ester; butyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 31 (fluorinated ester)	0.013	0.0011	11	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 31 (fluorinated ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 32 (fluorinated ester)	2.3 × 10⁻⁴	0.047	0.0048	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 32 (fluorinated ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 4 (alkyl ester)	0.024	0.0038	6.4	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 4 (alkyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 5 (alkyl ester)	0.0074	0.0044	1.7	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 5 (alkyl ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.11	0.0026	40	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 8 (polar ester)	0.093	0.0028	34	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 8 (polar ester)
MmLipN	Mycobacterium marinum	fluorogenic ester substrate 9 (polar ester)	0.12	0.003	39	pH 7.4	PMID 37065048	Open record: MmLipN, fluorogenic ester substrate 9 (polar ester)
MmLipN	Mycobacterium marinum	p-nitrophenyl acetate	94	2.4	39	pH 7.4, 25 °C	PMID 37065048	Open record: MmLipN, p-nitrophenyl acetate
MmLipN	Mycobacterium marinum	p-nitrophenyl butyrate	190	0.02	9.3 × 10³	pH 7.4, 25 °C	PMID 37065048	Open record: MmLipN, p-nitrophenyl butyrate
MmLipN	Mycobacterium marinum	p-nitrophenyl myristate	0.28	0.12	2.3	pH 7.4, 25 °C	PMID 37065048	Open record: MmLipN, p-nitrophenyl myristate
MmLipN	Mycobacterium marinum	p-nitrophenyl octanoate	1.1	0.41	2.7	pH 7.4, 25 °C	PMID 37065048	Open record: MmLipN, p-nitrophenyl octanoate
MmLipN	Mycobacterium marinum	p-nitrophenyl valerate	15	0.25	59	pH 7.4, 25 °C	PMID 37065048	Open record: MmLipN, p-nitrophenyl valerate
MmLipNvariant D215A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.0023	4.9 × 10⁻⁴	4.6	pH 7.4	PMID 37065048	Open record: MmLipN variant D215A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant D215A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.038	0.0025	16	pH 7.4	PMID 37065048	Open record: MmLipN variant D215A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant D215A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.039	0.0033	12	pH 7.4	PMID 37065048	Open record: MmLipN variant D215A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant D269A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.046	0.0057	1.7	pH 7.4	PMID 37065048	Open record: MmLipN variant D269A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant D269A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.0055	0.0058	0.96	pH 7.4	PMID 37065048	Open record: MmLipN variant D269A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant D269A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.032	0.015	2.2	pH 7.4	PMID 37065048	Open record: MmLipN variant D269A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant D312A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.0039	0.0057	4.3	pH 7.4	PMID 37065048	Open record: MmLipN variant D312A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant D312A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.19	0.028	6.7	pH 7.4	PMID 37065048	Open record: MmLipN variant D312A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant D312A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.31	0.035	9	pH 7.4	PMID 37065048	Open record: MmLipN variant D312A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant G144A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.0029	0.0015	2	pH 7.4	PMID 37065048	Open record: MmLipN variant G144A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant G144A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.017	0.0054	3.3	pH 7.4	PMID 37065048	Open record: MmLipN variant G144A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant G144A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.066	0.06	1.1	pH 7.4	PMID 37065048	Open record: MmLipN variant G144A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant G145A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.0019	3 × 10⁻⁴	6.2	pH 7.4	PMID 37065048	Open record: MmLipN variant G145A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant G145A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.045	0.0034	13	pH 7.4	PMID 37065048	Open record: MmLipN variant G145A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant G145A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.18	0.12	1.5	pH 7.4	PMID 37065048	Open record: MmLipN variant G145A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant H154A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.0024	0.0034	0.7	pH 7.4	PMID 37065048	Open record: MmLipN variant H154A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant H154A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.03	0.032	0.94	pH 7.4	PMID 37065048	Open record: MmLipN variant H154A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant H154A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.28	0.694	0.41	pH 7.4	PMID 37065048	Open record: MmLipN variant H154A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant H342A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	3.3 × 10⁻⁶	3.1 × 10⁻⁴	0.011	pH 7.4	PMID 37065048	Open record: MmLipN variant H342A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant H342A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	3.2 × 10⁻⁶	9.2 × 10⁻⁴	0.0035	pH 7.4	PMID 37065048	Open record: MmLipN variant H342A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant H342A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	5.3 × 10⁻⁵	0.02	0.0026	pH 7.4	PMID 37065048	Open record: MmLipN variant H342A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant R246A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.089	0.12	0.76	pH 7.4	PMID 37065048	Open record: MmLipN variant R246A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant R246A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.054	0.021	2.5	pH 7.4	PMID 37065048	Open record: MmLipN variant R246A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant R246A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.1	0.15	0.68	pH 7.4	PMID 37065048	Open record: MmLipN variant R246A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant S177A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.019	0.002	9.4	pH 7.4	PMID 37065048	Open record: MmLipN variant S177A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant S177A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	1.3	0.0011	110	pH 7.4	PMID 37065048	Open record: MmLipN variant S177A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant S177A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	1.8	0.0064	270	pH 7.4	PMID 37065048	Open record: MmLipN variant S177A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant S216C	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	6.1 × 10⁻⁵	0.12	5.3 × 10⁻⁴	pH 7.4	PMID 37065048	Open record: MmLipN variant S216C, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant S216C	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.0031	0.082	0.037	pH 7.4	PMID 37065048	Open record: MmLipN variant S216C, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant S216C	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.0032	0.06	0.053	pH 7.4	PMID 37065048	Open record: MmLipN variant S216C, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant S216G	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	2.1 × 10⁻⁵	0.0036	0.0057	pH 7.4	PMID 37065048	Open record: MmLipN variant S216G, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant S216G	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	7 × 10⁻⁴	0.021	0.034	pH 7.4	PMID 37065048	Open record: MmLipN variant S216G, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant S216G	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	1.8 × 10⁻⁴	0.022	0.082	pH 7.4	PMID 37065048	Open record: MmLipN variant S216G, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant S216N	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	1.2 × 10⁻⁴	0.026	0.015	pH 7.4	PMID 37065048	Open record: MmLipN variant S216N, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant S216N	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	8.2 × 10⁻⁴	0.026	0.031	pH 7.4	PMID 37065048	Open record: MmLipN variant S216N, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant S216N	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.0021	0.041	0.051	pH 7.4	PMID 37065048	Open record: MmLipN variant S216N, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant S226A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.017	0.0011	15	pH 7.4	PMID 37065048	Open record: MmLipN variant S226A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant S226A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	3.6	0.02	180	pH 7.4	PMID 37065048	Open record: MmLipN variant S226A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant S226A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	2.3	0.031	73	pH 7.4	PMID 37065048	Open record: MmLipN variant S226A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant W146A	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.0013	7.1 × 10⁻⁴	1.8	pH 7.4	PMID 37065048	Open record: MmLipN variant W146A, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant W146A	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.075	0.002	37	pH 7.4	PMID 37065048	Open record: MmLipN variant W146A, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant W146A	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.067	0.0011	62	pH 7.4	PMID 37065048	Open record: MmLipN variant W146A, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant W146C	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	6.1 × 10⁻⁵	0.12	5.3 × 10⁻⁴	pH 7.4	PMID 37065048	Open record: MmLipN variant W146C, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant W146C	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.013	0.023	0.57	pH 7.4	PMID 37065048	Open record: MmLipN variant W146C, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant W146C	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.15	0.013	11	pH 7.4	PMID 37065048	Open record: MmLipN variant W146C, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant W146Q	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.002	0.0035	0.55	pH 7.4	PMID 37065048	Open record: MmLipN variant W146Q, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant W146Q	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.064	0.0014	45	pH 7.4	PMID 37065048	Open record: MmLipN variant W146Q, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant W146Q	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.075	0.0022	34	pH 7.4	PMID 37065048	Open record: MmLipN variant W146Q, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)
MmLipNvariant W146S	Mycobacterium marinum	Fluorescein bis((5-oxazolyl)carboxymethyl ether)	0.0017	0.0035	0.5	pH 7.4	PMID 37065048	Open record: MmLipN variant W146S, Fluorescein bis((5-oxazolyl)carboxymethyl ether)
MmLipNvariant W146S	Mycobacterium marinum	fluorogenic ester substrate 1 (alkyl ester; acetyl ester)	0.091	0.023	4	pH 7.4	PMID 37065048	Open record: MmLipN variant W146S, fluorogenic ester substrate 1 (alkyl ester; acetyl ester)
MmLipNvariant W146S	Mycobacterium marinum	fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)	0.17	0.0041	42	pH 7.4	PMID 37065048	Open record: MmLipN variant W146S, fluorogenic ester substrate 7 (polar ester; four-atom chain polar/alkyl ether ester)