EC 3.1.1.81: quorum-quenching N-acyl-homoserine lactonase

HydrolasesOpen in Browse

CatLog read 126 records for EC 3.1.1.81 from 11 papers, for 9 organisms. Names in these papers: serum paraoxonase 1 (PON1), N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA), N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA), GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase) and 7 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 112 records for EC 3.1.1.81 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.1.81 in Browse.

Papers

Papers with records for EC 3.1.1.81
Paper	Organisms	Records
The histidine 115-histidine 134 dyad mediates the lactonase activity of mammalian serum paraoxonases	Oryctolagus cuniculus	23
Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 2. Substrate modeling and active site mutations	Bacillus thuringiensis	20
A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis	Bacillus thuringiensis	16
The Structural Determinants Accounting for the Broad Substrate Specificity of the Quorum Quenching Lactonase GcL	Parageobacillus caldoxylosilyticus	13
Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity	Chryseobacterium sp.	12
Lactonase-mediated inhibition of quorum sensing largely alters phenotypes, proteome, and antimicrobial activities in Burkholderia thailandensis E264	—	12
Specificity and enzyme kinetics of the quorum-quenching N-Acyl homoserine lactone lactonase (AHL-lactonase)	Bacillus sp.	10
MomL, a novel marine-derived N-acyl homoserine lactonase from Muricauda olearia	Muricauda olearia	8
Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties	Alicyclobacillus acidoterrestris	5
The quorum-quenching lactonase from Alicyclobacter acidoterrestris: purification, kinetic characterization, crystallization and crystallographic analysis	Alicyclobacter acidoterrestris	4
A Novel Screening System to Characterize and Engineer Quorum Quenching Lactonases	Bacillus thuringiensis serovar kurstaki	3

Records

Records for EC 3.1.1.81 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
AaL (quorum-quenching lactonase, metallo-beta-lactamase-like lactonase)	Alicyclobacter acidoterrestris	N-(3-oxododecanoyl)-homoserine lactone	5.03	0.014	360	pH 8.3, 25 °C	PMID 28777091	Open record: AaL (quorum-quenching lactonase, metallo-beta-lactamase-like lactonase), N-(3-oxododecanoyl)-homoserine lactone
AaL (quorum-quenching lactonase, metallo-beta-lactamase-like lactonase)	Alicyclobacter acidoterrestris	N-butanoyl-homoserine lactone	13.54	0.0105	1.29 × 10³	pH 8.3, 25 °C	PMID 28777091	Open record: AaL (quorum-quenching lactonase, metallo-beta-lactamase-like lactonase), N-butanoyl-homoserine lactone
AaL (quorum-quenching lactonase, metallo-beta-lactamase-like lactonase)	Alicyclobacter acidoterrestris	N-decanoyl-homoserine lactone	5.13	0.0496	103	pH 8.3, 25 °C	PMID 28777091	Open record: AaL (quorum-quenching lactonase, metallo-beta-lactamase-like lactonase), N-decanoyl-homoserine lactone
AaL (quorum-quenching lactonase, metallo-beta-lactamase-like lactonase)	Alicyclobacter acidoterrestris	N-hexanoyl-homoserine lactone	13.97	0.0827	169	pH 8.3, 25 °C	PMID 28777091	Open record: AaL (quorum-quenching lactonase, metallo-beta-lactamase-like lactonase), N-hexanoyl-homoserine lactone
AaL lactonase	Alicyclobacillus acidoterrestris	5-propyloxolan-2-one	7	0.0369	19	pH 8.3	PMID 30050039	Open record: AaL lactonase, 5-propyloxolan-2-one
AaL lactonase	Alicyclobacillus acidoterrestris	6-pentyloxan-2-one	8.4	0.0185	450	pH 8.3	PMID 30050039	Open record: AaL lactonase, 6-pentyloxan-2-one
AaL lactonase	Alicyclobacillus acidoterrestris	diethyl 4-nitrophenyl phosphate	—	—	0.0229	pH 8	PMID 30050039	Open record: AaL lactonase, diethyl 4-nitrophenyl phosphate
AaL lactonase	Alicyclobacillus acidoterrestris	oxan-2-one	8.4	0.0187	450	pH 8.3	PMID 30050039	Open record: AaL lactonase, oxan-2-one
AaL lactonase	Alicyclobacillus acidoterrestris	oxolan-2-one	23.5	0.171	140	pH 8.3	PMID 30050039	Open record: AaL lactonase, oxolan-2-one
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)	Bacillus sp.	N-(3-hydroxybutanoyl)-L-homoserine lactone	29.3	7.51	3.9	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase), N-(3-hydroxybutanoyl)-L-homoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)	Bacillus sp.	N-(3-oxobutanoyl)homoserine lactone	28.63	4.07	7.03	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase), N-(3-oxobutanoyl)homoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)	Bacillus sp.	N-(3-oxodecanoyl)homoserine lactone	20.22	1.43	14.1	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase), N-(3-oxodecanoyl)homoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)	Bacillus sp.	N-(3-oxohexanoyl)homoserine lactone	22.68	2.95	7.69	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase), N-(3-oxohexanoyl)homoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)	Bacillus sp.	N-(3-oxooctanoyl)homoserine lactone	22.17	2.28	9.72	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase), N-(3-oxooctanoyl)homoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)	Bacillus sp.	N-butanoylhomoserine lactone	37.63	5.11	7.36	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase), N-butanoylhomoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)	Bacillus sp.	N-hexanoylhomoserine lactone	35.67	3.83	9.31	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase), N-hexanoylhomoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)	Bacillus sp.	N-octanoylhomoserine lactone	27.53	2.61	10.5	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase), N-octanoylhomoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)variant H106S	Bacillus sp.	N-(3-oxooctanoyl)homoserine lactone	—	10.8	—	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase) variant H106S, N-(3-oxooctanoyl)homoserine lactone
AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase)variant H169S	Bacillus sp.	N-(3-oxooctanoyl)homoserine lactone	—	13.5	—	pH 7.4, 22 °C	PMID 14734559	Open record: AHL-lactonase (AiiA, N-acyl homoserine lactone lactonase) variant H169S, N-(3-oxooctanoyl)homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-3-oxo-octanoyl-L-homoserine lactone	28	0.13	220	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-3-oxo-octanoyl-L-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-butyryl-L-homoserine lactone	39	0.47	83	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-butyryl-L-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-cinnamoyl-(S)-homoserine lactone	25	0.47	53	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-cinnamoyl-(S)-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-decanoyl-(S)-homoserine lactone	5.2	0.012	430	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-decanoyl-(S)-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-dodecanoyl-(S)-homoserine lactone	0.4	0.007	57	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-dodecanoyl-(S)-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-heptanoyl-(S)-homoserine lactone	80	0.047	1.7 × 10³	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-heptanoyl-(S)-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-hexanoyl-(S)-homoserine lactonesupplemented with 30 μM ZnSO4 (dizinc AidC)	59	0.061	970	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-hexanoyl-(S)-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-hexanoyl-(S)-homoserine lactone	4.6	0.065	71 calc.	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-hexanoyl-(S)-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-octanoyl-(S)-homoserine lactone	45	0.083	540	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-octanoyl-(S)-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	N-pentanoyl-(S)-homoserine lactone	57	0.13	440	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), N-pentanoyl-(S)-homoserine lactone
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	tert-butyl(tetrahydro-2-oxo-3-furanyl)carbamate	44	0.74	59	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), tert-butyl(tetrahydro-2-oxo-3-furanyl)carbamate
AidC (N-acyl-L-homoserine lactone lactonase)	Chryseobacterium sp.	γ-butyrolactone	—	—	0.016	pH 7.5	PMID 26115006	Open record: AidC (N-acyl-L-homoserine lactone lactonase), γ-butyrolactone
AiiA	Bacillus thuringiensis serovar kurstaki	N-acetyl-D,L-homocysteine thiolactone	33.56	4.358	7.7	pH 8	PMID 39825575	Open record: AiiA, N-acetyl-D,L-homocysteine thiolactone
AiiA	Bacillus thuringiensis serovar kurstaki	N-butanoyl-L-homocysteine thiolactone	176.3	1.831	96.3	pH 8	PMID 39825575	Open record: AiiA, N-butanoyl-L-homocysteine thiolactone
AiiA	Bacillus thuringiensis serovar kurstaki	N-octanoyl-D,L-homocysteine thiolactone	260.3	0.5226	498	pH 8	PMID 39825575	Open record: AiiA, N-octanoyl-D,L-homocysteine thiolactone
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	5-butyl-4-methyloxolan-2-one	1	8.4 × 10⁻⁴	1.2 × 10⁴	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), 5-butyl-4-methyloxolan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	5-hexyloxolan-2-one	2.69	0.00714	380	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), 5-hexyloxolan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	5-pentyloxolan-2-one	20.5	0.0153	1.3 × 10³	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), 5-pentyloxolan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	5-propyloxolan-2-one	1.77	0.00201	880	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), 5-propyloxolan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	6-butyloxan-2-one	2.01	0.00805	250	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), 6-butyloxan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	6-pentyloxan-2-one	4.1	0.00313	1.3 × 10³	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), 6-pentyloxan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	6-propyloxan-2-one	12.58	0.0183	690	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), 6-propyloxan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	7-butyloxepan-2-one	1.09	0.00104	110	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), 7-butyloxepan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	diethyl 4-nitrophenyl phosphate	—	—	0.031	pH 8	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), diethyl 4-nitrophenyl phosphate
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	N-octanoyl-L-homoserine lactone	1.29	0.00312	410	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), N-octanoyl-L-homoserine lactone
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	oxan-2-one	1.24	0.00611	200	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), oxan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	oxepan-2-one	10.81	0.0247	440	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), oxepan-2-one
GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase)	Parageobacillus caldoxylosilyticus	oxolan-2-one	2.49	0.0101	250	pH 8.3, 25 °C	PMID 30864300	Open record: GcL (quorum quenching lactonase, metallo-beta-lactamase-like lactonase), oxolan-2-one
MomL (N-acyl homoserine lactonase)	Muricauda olearia	N-(3-oxodecanoyl)homoserine lactone	224	0.44	510	pH 7.1, 25 °C	PMID 25398866	Open record: MomL (N-acyl homoserine lactonase), N-(3-oxodecanoyl)homoserine lactone
MomL (N-acyl homoserine lactonase)	Muricauda olearia	N-(3-oxohexanoyl)homoserine lactone	293	0.95	310	pH 7.1, 25 °C	PMID 25398866	Open record: MomL (N-acyl homoserine lactonase), N-(3-oxohexanoyl)homoserine lactone
MomL (N-acyl homoserine lactonase)	Muricauda olearia	N-(3-oxooctanoyl)homoserine lactone	218	0.49	450	pH 7.1, 25 °C	PMID 25398866	Open record: MomL (N-acyl homoserine lactonase), N-(3-oxooctanoyl)homoserine lactone
MomL (N-acyl homoserine lactonase)	Muricauda olearia	N-butanoylhomoserine lactone	135	0.85	160	pH 7.1, 25 °C	PMID 25398866	Open record: MomL (N-acyl homoserine lactonase), N-butanoylhomoserine lactone
MomL (N-acyl homoserine lactonase)	Muricauda olearia	N-hexanoyl-L-homoserine lactonewithout metal supplement	226	0.79	290	pH 7.1, 25 °C	PMID 25398866	Open record: MomL (N-acyl homoserine lactonase), N-hexanoyl-L-homoserine lactone
MomL (N-acyl homoserine lactonase)	Muricauda olearia	N-hexanoyl-L-homoserine lactonesupplemented with 0.2 mM ZnCl2	454	0.74	610	pH 7.1, 25 °C	PMID 25398866	Open record: MomL (N-acyl homoserine lactonase), N-hexanoyl-L-homoserine lactone
MomL (N-acyl homoserine lactonase)	Muricauda olearia	N-hexanoyl-L-homoserine lactonesupplemented with 0.05 mM CoCl2	407	0.45	900	pH 7.1, 25 °C	PMID 25398866	Open record: MomL (N-acyl homoserine lactonase), N-hexanoyl-L-homoserine lactone
MomL (N-acyl homoserine lactonase)	Muricauda olearia	N-octanoylhomoserine lactone	158	0.44	360	pH 7.1, 25 °C	PMID 25398866	Open record: MomL (N-acyl homoserine lactonase), N-octanoylhomoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-decanoyl-(S)-homoserine lactone	54	0.14	390	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA), N-decanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-heptanoyl-(S)-homoserine lactone	34	0.3	110	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA), N-heptanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-hexanoyl-(S)-homoserine lactone	36	2.1	17	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA), N-hexanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-octanoyl-(S)-homoserine lactonedizinc enzyme	34	0.18	190	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA), N-octanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-octanoyl-(S)-homoserine lactonewith 2 mM DTT	57	0.7	81	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA), N-octanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactonedizinc enzyme	43	3	14	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA), N-pentanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactonewith 2 mM DTT	45	6	7.5	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA), N-pentanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F107W	Bacillus thuringiensis	N-decanoyl-(S)-homoserine lactone	0.32	0.15	2.1	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F107W, N-decanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F107W	Bacillus thuringiensis	N-heptanoyl-(S)-homoserine lactone	0.3	1.6	0.19	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F107W, N-heptanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F107W	Bacillus thuringiensis	N-hexanoyl-(S)-homoserine lactone	0.257	10	0.026	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F107W, N-hexanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F107W	Bacillus thuringiensis	N-octanoyl-(S)-homoserine lactone	0.46	0.8	0.58	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F107W, N-octanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F107W	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactone	0.08	6	0.012	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F107W, N-pentanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F64C/F68C	Bacillus thuringiensis	N-octanoyl-(S)-homoserine lactonewithout DTT	0.83	0.7	1.2	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F64C/F68C, N-octanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F64C/F68C	Bacillus thuringiensis	N-octanoyl-(S)-homoserine lactonewith 2 mM DTT	8.2	0.26	32	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F64C/F68C, N-octanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F64C/F68C	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactonewithout DTT	3	4.5	0.67	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F64C/F68C, N-pentanoyl-(S)-homoserine lactone
N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA)variant F64C/F68C	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactonewith 2 mM DTT	6.1	1.8	3.4	pH 7.5	PMID 23387521	Open record: N-acyl homoserine lactone hydrolase (AHL lactonase, AiiA) variant F64C/F68C, N-pentanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	gamma-butyrolactone	5.9	303	0.02		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA), gamma-butyrolactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-(benzyloxycarbonyl)-L-homoserine lactone	790	0.48	1.6 × 10³		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA), N-(benzyloxycarbonyl)-L-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-(tert-butyloxycarbonyl)-DL-homoserine lactone	185	3.8	49		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA), N-(tert-butyloxycarbonyl)-DL-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-decanoyl-(S)-homoserine lactone	650	0.15	4.3 × 10³		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA), N-decanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactone	490	0.8	610		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA), N-pentanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant A206W	Bacillus thuringiensis	gamma-butyrolactone	3.4	200	0.017		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant A206W, gamma-butyrolactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant A206W	Bacillus thuringiensis	N-decanoyl-(S)-homoserine lactone	106	0.08	1.3 × 10³		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant A206W, N-decanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant A206W	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactone	148	0.32	460		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant A206W, N-pentanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant D108N	Bacillus thuringiensis	N-hexanoyl-DL-homocysteine thiolactone	1.11	1.3	0.85		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant D108N, N-hexanoyl-DL-homocysteine thiolactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant D108N	Bacillus thuringiensis	N-hexanoyl-L-homoserine lactone	1.4	1.6	0.88		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant D108N, N-hexanoyl-L-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant D108N	Bacillus thuringiensis	N-hexanoyl-L-homoserine lactone	3.5	0.09	39		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant D108N, N-hexanoyl-L-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant G207D	Bacillus thuringiensis	gamma-butyrolactone	1.4	210	0.006		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant G207D, gamma-butyrolactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant G207D	Bacillus thuringiensis	N-decanoyl-(S)-homoserine lactone	500	0.24	2.1 × 10³		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant G207D, N-decanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant G207D	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactone	650	3.5	170		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant G207D, N-pentanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant G207W	Bacillus thuringiensis	gamma-butyrolactone	3.3	115	0.03		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant G207W, gamma-butyrolactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant G207W	Bacillus thuringiensis	N-decanoyl-(S)-homoserine lactone	123	0.015	8.2 × 10³		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant G207W, N-decanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant G207W	Bacillus thuringiensis	N-pentanoyl-(S)-homoserine lactone	263	0.7	380		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant G207W, N-pentanoyl-(S)-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant Y194F	Bacillus thuringiensis	N-hexanoyl-DL-homocysteine thiolactone	5.4	0.6	9		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant Y194F, N-hexanoyl-DL-homocysteine thiolactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant Y194F	Bacillus thuringiensis	N-hexanoyl-L-homoserine lactone	0.31	2.1	0.15		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant Y194F, N-hexanoyl-L-homoserine lactone
N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA)variant Y194F	Bacillus thuringiensis	N-hexanoyl-L-homoserine lactone	16.6	2	8.3		PMID 18627130	Open record: N-acyl-L-homoserine lactone hydrolase (AHL lactonase, AiiA) variant Y194F, N-hexanoyl-L-homoserine lactone
serum paraoxonase 1 (PON1)	Oryctolagus cuniculus	5-(thiobutyl)butyrolactone	116	0.27	440	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1), 5-(thiobutyl)butyrolactone
serum paraoxonase 1 (PON1)	Oryctolagus cuniculus	5-(thiobutyl)butyrolactone	104	—	750		PMID 16407305	Open record: serum paraoxonase 1 (PON1), 5-(thiobutyl)butyrolactone
serum paraoxonase 1 (PON1)	Oryctolagus cuniculus	paraoxon	4.2	0.86	4.89	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1), paraoxon
serum paraoxonase 1 (PON1)	Oryctolagus cuniculus	phenyl acetate	854	1.3	668	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1), phenyl acetate
serum paraoxonase 1 (PON1)	Oryctolagus cuniculus	γ-caprolactone	44	1	43	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1), γ-caprolactone
serum paraoxonase 1 (PON1)	Oryctolagus cuniculus	γ-nonalactone	31	0.39	78	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1), γ-nonalactone
serum paraoxonase 1 (PON1)	Oryctolagus cuniculus	δ-valerolactone	210	0.57	370	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1), δ-valerolactone
serum paraoxonase 1 (PON1)variant H115Q	Oryctolagus cuniculus	5-(thiobutyl)butyrolactone	7.6	1.6	4.72	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q, 5-(thiobutyl)butyrolactone
serum paraoxonase 1 (PON1)variant H115Q	Oryctolagus cuniculus	paraoxon	1	1.35	0.738	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q, paraoxon
serum paraoxonase 1 (PON1)variant H115Q	Oryctolagus cuniculus	phenyl acetate	10.5	8.1	1.31	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q, phenyl acetate
serum paraoxonase 1 (PON1)variant H115Q	Oryctolagus cuniculus	γ-caprolactone	2.27	3.8	0.6	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q, γ-caprolactone
serum paraoxonase 1 (PON1)variant H115Q	Oryctolagus cuniculus	γ-nonalactone	0.38	1.54	0.25	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q, γ-nonalactone
serum paraoxonase 1 (PON1)variant H115Q	Oryctolagus cuniculus	δ-valerolactone	69.4	8.5	8.2	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q, δ-valerolactone
serum paraoxonase 1 (PON1)variant H115Q/H134Q	Oryctolagus cuniculus	5-(thiobutyl)butyrolactone	1.74	1.83	0.965	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q/H134Q, 5-(thiobutyl)butyrolactone
serum paraoxonase 1 (PON1)variant H115Q/H134Q	Oryctolagus cuniculus	paraoxon	4.7	1.18	3.98	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q/H134Q, paraoxon
serum paraoxonase 1 (PON1)variant H115Q/H134Q	Oryctolagus cuniculus	phenyl acetate	7.4	9.7	0.773	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q/H134Q, phenyl acetate
serum paraoxonase 1 (PON1)variant H115Q/H134Q	Oryctolagus cuniculus	δ-valerolactone	—	—	2.97	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H115Q/H134Q, δ-valerolactone
serum paraoxonase 1 (PON1)variant H134Q	Oryctolagus cuniculus	5-(thiobutyl)butyrolactone	19.4	0.68	28.6	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H134Q, 5-(thiobutyl)butyrolactone
serum paraoxonase 1 (PON1)variant H134Q	Oryctolagus cuniculus	paraoxon	12.7	0.75	17	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H134Q, paraoxon
serum paraoxonase 1 (PON1)variant H134Q	Oryctolagus cuniculus	phenyl acetate	185	3.6	50.9	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H134Q, phenyl acetate
serum paraoxonase 1 (PON1)variant H134Q	Oryctolagus cuniculus	γ-caprolactone	25	2.97	8.4	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H134Q, γ-caprolactone
serum paraoxonase 1 (PON1)variant H134Q	Oryctolagus cuniculus	γ-nonalactone	5.57	0.89	6.24	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H134Q, γ-nonalactone
serum paraoxonase 1 (PON1)variant H134Q	Oryctolagus cuniculus	δ-valerolactone	40	0.95	42.2	pH 8	PMID 16407305	Open record: serum paraoxonase 1 (PON1) variant H134Q, δ-valerolactone
SsoPoxvariant V82I	—	3-OH-C10-HSL	0.06	0.04386	1.48	pH 8.3	PMID 37333853	Open record: SsoPox variant V82I, 3-OH-C10-HSL
SsoPoxvariant V82I	—	3-OH-C8-HSL	0.9	0.3016	2.98	pH 8.3	PMID 37333853	Open record: SsoPox variant V82I, 3-OH-C8-HSL
SsoPoxvariant V82I	—	C8-HSL	3.01	0.06363	47.2	pH 8.3	PMID 37333853	Open record: SsoPox variant V82I, C8-HSL
SsoPoxvariant V82I/A275G	—	3-OH-C10-HSL	0.12	0.2242	0.529	pH 8.3	PMID 37333853	Open record: SsoPox variant V82I/A275G, 3-OH-C10-HSL
SsoPoxvariant V82I/A275G	—	3-OH-C8-HSL	0.15	1.394	0.107	pH 8.3	PMID 37333853	Open record: SsoPox variant V82I/A275G, 3-OH-C8-HSL
SsoPoxvariant V82I/A275G	—	C8-HSL	1.74	1.373	1.27	pH 8.3	PMID 37333853	Open record: SsoPox variant V82I/A275G, C8-HSL
SsoPoxvariant W263F	—	3-OH-C10-HSL	1.12	0.3205	3.49	pH 8.3	PMID 37333853	Open record: SsoPox variant W263F, 3-OH-C10-HSL
SsoPoxvariant W263F	—	3-OH-C8-HSL	1.56	0.56	2.79	pH 8.3	PMID 37333853	Open record: SsoPox variant W263F, 3-OH-C8-HSL
SsoPoxvariant W263F	—	C8-HSL	0.03	0.3607	0.0739	pH 8.3	PMID 37333853	Open record: SsoPox variant W263F, C8-HSL
SsoPoxvariant W263I	—	3-OH-C10-HSL	0.1	0.4909	0.21	pH 8.3	PMID 37333853	Open record: SsoPox variant W263I, 3-OH-C10-HSL
SsoPoxvariant W263I	—	3-OH-C8-HSL	0.21	1.135	0.188	pH 8.3	PMID 37333853	Open record: SsoPox variant W263I, 3-OH-C8-HSL
SsoPoxvariant W263I	—	C8-HSL	1.03	0.179	5.75	pH 8.3	PMID 37333853	Open record: SsoPox variant W263I, C8-HSL