EC 3.1.26.13: retroviral ribonuclease H

HydrolasesOpen in Browse

CatLog read 7 records for EC 3.1.26.13 from 1 paper, for 1 organism. Names in these papers: HIV-1 reverse transcriptase (RNase H activity).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 8 records for EC 3.1.26.13 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.26.13 in Browse.

Papers

Papers with records for EC 3.1.26.13
Paper	Organisms	Records
Mutagenesis of cysteine 280 of the reverse transcriptase of human immunodeficiency virus type-1: the effects on the ribonuclease H activity	human immunodeficiency virus type 1	7

Records

Records for EC 3.1.26.13 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
HIV-1 reverse transcriptase (RNase H activity)	human immunodeficiency virus type 1	polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)	0.031	0.003	10.3	37 °C	PMID 12614605	Open record: HIV-1 reverse transcriptase (RNase H activity), polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)
HIV-1 reverse transcriptase (RNase H activity)variant p66/p51C280P	human immunodeficiency virus type 1	polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)	0.024	0.0257	0.93	37 °C	PMID 12614605	Open record: HIV-1 reverse transcriptase (RNase H activity) variant p66/p51C280P, polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)
HIV-1 reverse transcriptase (RNase H activity)variant p66/p51C280W	human immunodeficiency virus type 1	polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)	0.024	0.0383	0.62	37 °C	PMID 12614605	Open record: HIV-1 reverse transcriptase (RNase H activity) variant p66/p51C280W, polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)
HIV-1 reverse transcriptase (RNase H activity)variant p66C280P/p51	human immunodeficiency virus type 1	polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)	0.025	0.0177	1.46	37 °C	PMID 12614605	Open record: HIV-1 reverse transcriptase (RNase H activity) variant p66C280P/p51, polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)
HIV-1 reverse transcriptase (RNase H activity)variant p66C280P/p51C280P	human immunodeficiency virus type 1	polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)	0.029	0.0553	0.52	37 °C	PMID 12614605	Open record: HIV-1 reverse transcriptase (RNase H activity) variant p66C280P/p51C280P, polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)
HIV-1 reverse transcriptase (RNase H activity)variant p66C280W/p51	human immunodeficiency virus type 1	polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)	0.029	0.0318	0.91	37 °C	PMID 12614605	Open record: HIV-1 reverse transcriptase (RNase H activity) variant p66C280W/p51, polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)
HIV-1 reverse transcriptase (RNase H activity)variant p66C280W/p51C280W	human immunodeficiency virus type 1	polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)	0.034	0.0663	0.51	37 °C	PMID 12614605	Open record: HIV-1 reverse transcriptase (RNase H activity) variant p66C280W/p51C280W, polyriboadenylic acid annealed to polydeoxythymidylic acid (poly(rA)·poly(dT) RNA·DNA heteroduplex)