EC 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase

HydrolasesOpen in Browse

CatLog read 46 records for EC 3.1.4.37 from 6 papers, for 4 organisms. Names in these papers: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain, 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1), DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 16 records for EC 3.1.4.37 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.4.37 in Browse.

Papers

Papers with records for EC 3.1.4.37
Paper	Organisms	Records
Identification of essential residues in 2',3'-cyclic nucleotide 3'-phosphodiesterase. Chemical modification and site-directed mutagenesis to investigate the role of cysteine and histidine residues…	Rattus norvegicus	16
Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase	Mus musculus	12
Structural and enzymatic characterization of DR1281: A calcineurin-like phosphoesterase from Deinococcus radiodurans	Deinococcus radiodurans	8
Crystallographic analysis of the reaction cycle of 2',3'-cyclic nucleotide 3'-phosphodiesterase, a unique member of the 2H phosphoesterase family	Mus musculus	5
Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies	Mus musculus	4
Characterization of the 2',3' cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase	Clostridium thermocellum	1

Records

Records for EC 3.1.4.37 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)	Rattus norvegicus	2',3'-cyclic NADPHis6-tagged full-length CNP1 (pTrcHisC); Table I	836	0.263	3.2 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1), 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)	Rattus norvegicus	2',3'-cyclic NADPTable I	1678	0.106	1.58 × 10⁴	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1), 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)	Rattus norvegicus	2',3'-cyclic NADPTable I	1.69 × 10³	0.295	5.7 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1), 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)	Rattus norvegicus	2',3'-cyclic NADPTable I	1952	0.126	1.55 × 10⁴	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1), 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)	Rattus norvegicus	2',3'-cyclic NADPTable II	1195	0.237	5 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1), 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant C231A	Rattus norvegicus	2',3'-cyclic NADP	968	0.231	4.2 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant C231A, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant C231S	Rattus norvegicus	2',3'-cyclic NADP	825	0.473	1.7 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant C231S, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant C236A	Rattus norvegicus	2',3'-cyclic NADP	1476	0.354	4.2 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant C236A, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant C236S	Rattus norvegicus	2',3'-cyclic NADP	1107	0.379	2.9 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant C236S, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant C314A	Rattus norvegicus	2',3'-cyclic NADP	1116	0.333	3.4 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant C314A, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant C314S	Rattus norvegicus	2',3'-cyclic NADP	594	0.241	2.5 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant C314S, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant C397S	Rattus norvegicus	2',3'-cyclic NADP	1132	0.297	3.8 × 10³	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant C397S, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant H230F	Rattus norvegicus	2',3'-cyclic NADP	1.15	0.119	10	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant H230F, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant H230L	Rattus norvegicus	2',3'-cyclic NADP	1.16	0.104	11	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant H230L, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant H309F	Rattus norvegicus	2',3'-cyclic NADP	1.35	0.1	13	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant H309F, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1)variant H309L	Rattus norvegicus	2',3'-cyclic NADP	1.27	0.098	13	pH 6, 25 °C	PMID 11278504	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP1) variant H309L, 2',3'-cyclic NADP
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain	Mus musculus	2',3'-cyclic NADP+	940	0.553	1.7 × 10³		PMID 23831225	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain, 2',3'-cyclic NADP+
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphatereaction solvent H2O	807	0.423	1.91 × 10³		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphatereaction solvent D2O	273	0.147	1.85 × 10³		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphatereaction solvent H2O; His-tag cleaved	893	0.382	2.34 × 10³		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphatereaction solvent D2O; His-tag cleaved	326	0.204	1.59 × 10³		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant F235A	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphate	183	6.253	30		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant F235A, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant F235L	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphate	221	3.788	60		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant F235L, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant H230Q	Mus musculus	2',3'-cyclic NADP+	24	1.055	20		PMID 23831225	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant H230Q, 2',3'-cyclic NADP+
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant H230S	Mus musculus	2',3'-cyclic NADP+	14	1.305	10		PMID 23831225	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant H230S, 2',3'-cyclic NADP+
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant H309S	Mus musculus	2',3'-cyclic NADP+	21	1.192	20		PMID 23831225	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant H309S, 2',3'-cyclic NADP+
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant P225G	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphate	1.42 × 10³	0.483	2.94 × 10³		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant P225G, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant P296G	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphate	1332	0.722	1.73 × 10³		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant P296G, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant R307Q	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphate	1182	2.192	540		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant R307Q, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant T232A	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphate	231	39.65	5.83 calc.		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant T232A, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant V321A	Mus musculus	2',3'-cyclic NADP+	732	1.045	700		PMID 23831225	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant V321A, 2',3'-cyclic NADP+
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant Y168A	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphate	237	1.879	130		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant Y168A, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domainvariant Y168S	Mus musculus	nicotinamide adenine dinucleotide 2',3'-cyclic phosphate	887	1.385	640		PMID 26563764	Open record: 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain variant Y168S, nicotinamide adenine dinucleotide 2',3'-cyclic phosphate
2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length	Mus musculus	2′,3′-cyclic NADP+enzyme alone (apo, no nanobody); full-length	578.7	0.4829	1.2 × 10³	pH 6, 25 °C	PMID 39655780	Open record: 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length, 2′,3′-cyclic NADP+
2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length	Mus musculus	2′,3′-cyclic NADP+	596	0.4819	1.24 × 10³	pH 6, 25 °C	PMID 39655780	Open record: 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length, 2′,3′-cyclic NADP+
2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length	Mus musculus	2′,3′-cyclic NADP+	773.4	0.4119	1.88 × 10³	pH 6, 25 °C	PMID 39655780	Open record: 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length, 2′,3′-cyclic NADP+
2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length	Mus musculus	2′,3′-cyclic NADP+in complex with nanobody NbCNP-10E; apparent kcat	205.6	0.4389	469	pH 6, 25 °C	PMID 39655780	Open record: 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase), full-length, 2′,3′-cyclic NADP+
CthPnkp (polynucleotide kinase-phosphatase)variant D392A	Clostridium thermocellum	adenosine 2',3'-cyclic monophosphate	1.77	100	0.018 calc.	pH 7.5, 45 °C	PMID 17986465	Open record: CthPnkp (polynucleotide kinase-phosphatase) variant D392A, adenosine 2',3'-cyclic monophosphate
DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase)	Deinococcus radiodurans	adenosine 2',3'-cyclic monophosphate	0.38	0.55	0.69	pH 6.5, 37 °C	PMID 17847097	Open record: DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), adenosine 2',3'-cyclic monophosphate
DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase)	Deinococcus radiodurans	bis(p-nitrophenyl) phosphate	6.97	0.22	31.7	pH 8.5	PMID 17847097	Open record: DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), bis(p-nitrophenyl) phosphate
DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase)	Deinococcus radiodurans	bis(p-nitrophenyl) phosphate	1.23	0.06	20.5	pH 6.5	PMID 17847097	Open record: DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), bis(p-nitrophenyl) phosphate
DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase)	Deinococcus radiodurans	cytidine 2',3'-cyclic monophosphate	0.32	0.87	0.4	pH 6.5, 37 °C	PMID 17847097	Open record: DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), cytidine 2',3'-cyclic monophosphate
DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase)	Deinococcus radiodurans	guanosine 2',3'-cyclic monophosphate	0.42	1.28	0.33	pH 6.5, 37 °C	PMID 17847097	Open record: DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), guanosine 2',3'-cyclic monophosphate
DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase)	Deinococcus radiodurans	p-nitrophenyl phosphate	0.2	0.08	2.5	pH 8.5	PMID 17847097	Open record: DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), p-nitrophenyl phosphate
DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase)	Deinococcus radiodurans	p-nitrophenyl thymidine 5'-monophosphate	1.41	0.05	26.1	pH 8.5	PMID 17847097	Open record: DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), p-nitrophenyl thymidine 5'-monophosphate
DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase)	Deinococcus radiodurans	phosphoenolpyruvate	0.18	0.36	0.5	pH 6.5, 37 °C	PMID 17847097	Open record: DR1281 (calcineurin-like phosphoesterase; phosphatase/phosphodiesterase), phosphoenolpyruvate