EC 3.13.2.1: adenosylhomocysteinase
HydrolasesOpen in Browse
CatLog read 19 records for EC 3.13.2.1 from 2 papers, for 2 organisms. Names in these papers: S-adenosylhomocysteine hydrolase (SAHH), S-adenosyl-L-homocysteine hydrolase (PaSAHase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 48 records for EC 3.13.2.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.13.2.1 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation | Homo sapiens | 12 |
| Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| S-adenosyl-L-homocysteine hydrolase (PaSAHase) | Pseudomonas aeruginosa | S-adenosyl-L-homocysteine100 mM Tris·HCl pH 7.5; no alkali metal cation | 0.0529 | 0.1011 | 0.523 | pH 7.5, 20 °C | PMID 30054521 | Open record: S-adenosyl-L-homocysteine hydrolase (PaSAHase), S-adenosyl-L-homocysteine |
| S-adenosyl-L-homocysteine hydrolase (PaSAHase) | Pseudomonas aeruginosa | S-adenosyl-L-homocysteine100 mM LiCl; 25 mM HEPES·LiOH pH 7.5 | 0.0466 | 0.0638 | 0.731 | pH 7.5, 20 °C | PMID 30054521 | Open record: S-adenosyl-L-homocysteine hydrolase (PaSAHase), S-adenosyl-L-homocysteine |
| S-adenosyl-L-homocysteine hydrolase (PaSAHase) | Pseudomonas aeruginosa | S-adenosyl-L-homocysteine100 mM NaCl; 25 mM HEPES·NaOH pH 7.5 | 0.2373 | 0.028 | 8.467 | pH 7.5, 20 °C | PMID 30054521 | Open record: S-adenosyl-L-homocysteine hydrolase (PaSAHase), S-adenosyl-L-homocysteine |
| S-adenosyl-L-homocysteine hydrolase (PaSAHase) | Pseudomonas aeruginosa | S-adenosyl-L-homocysteine100 mM KCl; 25 mM HEPES·KOH pH 7.5 | 0.575 | 0.0079 | 72.50 | pH 7.5, 20 °C | PMID 30054521 | Open record: S-adenosyl-L-homocysteine hydrolase (PaSAHase), S-adenosyl-L-homocysteine |
| S-adenosyl-L-homocysteine hydrolase (PaSAHase) | Pseudomonas aeruginosa | S-adenosyl-L-homocysteine100 mM RbCl; 25 mM HEPES·RbOH pH 7.5 | 0.0175 | 0.0049 | 3.568 | pH 7.5, 20 °C | PMID 30054521 | Open record: S-adenosyl-L-homocysteine hydrolase (PaSAHase), S-adenosyl-L-homocysteine |
| S-adenosyl-L-homocysteine hydrolase (PaSAHase) | Pseudomonas aeruginosa | S-adenosyl-L-homocysteine100 mM CsCl; 25 mM HEPES·CsOH pH 7.5 | 0.2131 | 0.032 | 6.668 | pH 7.5, 20 °C | PMID 30054521 | Open record: S-adenosyl-L-homocysteine hydrolase (PaSAHase), S-adenosyl-L-homocysteine |
| S-adenosyl-L-homocysteine hydrolase (PaSAHase)variant Q65A | Pseudomonas aeruginosa | S-adenosyl-L-homocysteine | 0.14 | 0.0262 | 5.322 | pH 7.5, 20 °C | PMID 30054521 | Open record: S-adenosyl-L-homocysteine hydrolase (PaSAHase) variant Q65A, S-adenosyl-L-homocysteine |
| S-adenosylhomocysteine hydrolase (SAHH) | Homo sapiens | adenosine | 2 | — | — | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH), adenosine |
| S-adenosylhomocysteine hydrolase (SAHH) | Homo sapiens | S-adenosylhomocysteine | 0.79 | 0.0139 | 57 | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH), S-adenosylhomocysteine |
| S-adenosylhomocysteine hydrolase (SAHH)variant D293A | Homo sapiens | S-adenosylhomocysteine | 0.56 | 0.0334 | 17 | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant D293A, S-adenosylhomocysteine |
| S-adenosylhomocysteine hydrolase (SAHH)variant E396C (s-SAHH, unacetylated) | Homo sapiens | adenosine | 3.1 | — | — | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant E396C (s-SAHH, unacetylated), adenosine |
| S-adenosylhomocysteine hydrolase (SAHH)variant E396C (s-SAHH, unacetylated) | Homo sapiens | S-adenosylhomocysteine | 1.04 | 0.0129 | 81 | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant E396C (s-SAHH, unacetylated), S-adenosylhomocysteine |
| S-adenosylhomocysteine hydrolase (SAHH)variant E396C, acetyl-Lys401 (AcK401-s-SAHH) | Homo sapiens | adenosine | 1.2 | — | — | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant E396C, acetyl-Lys401 (AcK401-s-SAHH), adenosine |
| S-adenosylhomocysteine hydrolase (SAHH)variant E396C, acetyl-Lys401 (AcK401-s-SAHH) | Homo sapiens | S-adenosylhomocysteine | 0.34 | 0.0123 | 28 | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant E396C, acetyl-Lys401 (AcK401-s-SAHH), S-adenosylhomocysteine |
| S-adenosylhomocysteine hydrolase (SAHH)variant E396C, acetyl-Lys401, acetyl-Lys408 (biAcK401/408-s-SAHH) | Homo sapiens | adenosine | 1.2 | — | — | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant E396C, acetyl-Lys401, acetyl-Lys408 (biAcK401/408-s-SAHH), adenosine |
| S-adenosylhomocysteine hydrolase (SAHH)variant E396C, acetyl-Lys401, acetyl-Lys408 (biAcK401/408-s-SAHH) | Homo sapiens | S-adenosylhomocysteine | 0.36 | 0.0236 | 15 | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant E396C, acetyl-Lys401, acetyl-Lys408 (biAcK401/408-s-SAHH), S-adenosylhomocysteine |
| S-adenosylhomocysteine hydrolase (SAHH)variant E396C, acetyl-Lys408 (AcK408-s-SAHH) | Homo sapiens | adenosine | 1 | — | — | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant E396C, acetyl-Lys408 (AcK408-s-SAHH), adenosine |
| S-adenosylhomocysteine hydrolase (SAHH)variant E396C, acetyl-Lys408 (AcK408-s-SAHH) | Homo sapiens | S-adenosylhomocysteine | 0.3 | 0.0088 | 34 | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant E396C, acetyl-Lys408 (AcK408-s-SAHH), S-adenosylhomocysteine |
| S-adenosylhomocysteine hydrolase (SAHH)variant N27K | Homo sapiens | S-adenosylhomocysteine | 0.4 | 0.0231 | 17 | pH 7.2, 37 °C | PMID 25248746 | Open record: S-adenosylhomocysteine hydrolase (SAHH) variant N27K, S-adenosylhomocysteine |