CatLogenzyme kinetics catalog

EC 3.2.1.49: alpha-N-acetylgalactosaminidase

HydrolasesOpen in Browse

CatLog read 17 records for EC 3.2.1.49 from 2 papers, for 2 organisms. Names in these papers: EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain), NagBb (alpha-N-acetylgalactosaminidase, GH129).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 34 records for EC 3.2.1.49 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.2.1.49 in Browse.

Papers

PaperOrganismsRecords
Structural and mechanistic insights into the substrate specificity and hydrolysis of GH31 α-N-acetylgalactosaminidaseEnterococcus faecalis10
α-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathwayBifidobacterium bifidum7

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant D455AEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide0.010.07340.14PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant D455NEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide0.002390.02320.1PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant D508NEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide0.002310.01720.13PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant I542FEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide2.042.230.92PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant L492REnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide0.01750.07940.22PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant V456AEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide1.40.10114PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant W221NEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide3.793.861PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant W570AEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide2.894.440.65PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant Y386AEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide0.05062.360.021PMID 34826537Open
EfGH31 (GH31 α-N-acetylgalactosaminidase EfNag31A catalytic domain)variant Y386FEnterococcus faecalis4-nitrophenyl α-N-acetylgalactosaminide0.08510.061.4PMID 34826537Open
NagBb (alpha-N-acetylgalactosaminidase, GH129)Bifidobacterium bifidum4,6-dimethoxy-1,3,5-triazin-2-yl 2-acetamido-2-deoxy-alpha-D-galactopyranoside16.717.10.98pH 5, 37 °CPMID 22090027Open
NagBb (alpha-N-acetylgalactosaminidase, GH129)Bifidobacterium bifidum4-nitrophenyl 2-acetamido-2-deoxy-3-O-(beta-D-galactopyranosyl)-alpha-D-galactopyranoside——0.08pH 5, 37 °CPMID 22090027Open
NagBb (alpha-N-acetylgalactosaminidase, GH129)Bifidobacterium bifidum4-nitrophenyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside——2.35pH 5, 37 °CPMID 22090027Open
NagBb (alpha-N-acetylgalactosaminidase, GH129)Bifidobacterium bifidum4-nitrophenyl 2-acetamido-3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-alpha-D-galactopyranoside——0.03pH 5, 37 °CPMID 22090027Open
NagBb (alpha-N-acetylgalactosaminidase, GH129)Bifidobacterium bifidumGalNAcα1-Ser (Tn antigen)47.62.221.6pH 5, 37 °CPMID 22090027Open
NagBb (alpha-N-acetylgalactosaminidase, GH129)Bifidobacterium bifidumGalNAcα1–3Galβ1–4Glc——0.03pH 5, 37 °CPMID 22090027Open
NagBb (alpha-N-acetylgalactosaminidase, GH129)Bifidobacterium bifidumUDP-N-acetyl-alpha-D-galactosamine——0.02pH 5, 37 °CPMID 22090027Open