EC 3.3.1.1: adenosylhomocysteinase

HydrolasesOpen in Browse

CatLog read 26 records for EC 3.3.1.1 from 3 papers, for 3 organisms. Names in these papers: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase), S-adenosylhomocysteine hydrolase (PfAdoHcyHD), Tm0172.

EC 3.3.1.1 is no longer current; BRENDA: “transferred, now EC 3.13.2.1”.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 12 records for EC 3.3.1.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.3.1.1 in Browse.

Papers

Papers with records for EC 3.3.1.1
Paper	Organisms	Records
Chemical modification and site-directed mutagenesis of cysteine residues in human placental S-adenosylhomocysteine hydrolase	Homo sapiens	21
S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: biochemical characterization and analysis of protein structure by comparative molecular modeling	Pyrococcus furiosus	3
Structure-based activity prediction for an enzyme of unknown function	Thermotoga maritima	2

Records

Records for EC 3.3.1.1 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)	Homo sapiens	adenosine	9.7	0.0014	6.9 × 10³	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase), adenosine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)	Homo sapiens	L-homocysteine	9.8	0.0881	110	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase), L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)	Homo sapiens	S-adenosyl-L-homocysteine	3.8	0.0079	480	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase), S-adenosyl-L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C113D	Homo sapiens	adenosine	9.1	0.0018	5.1 × 10³	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C113D, adenosine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C113D	Homo sapiens	L-homocysteine	9.2	0.0997	90	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C113D, L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C113D	Homo sapiens	S-adenosyl-L-homocysteine	2.8	0.0105	270	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C113D, S-adenosyl-L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C113S	Homo sapiens	adenosine	9.2	0.0019	4.9 × 10³	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C113S, adenosine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C113S	Homo sapiens	L-homocysteine	9.3	0.0925	100	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C113S, L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C113S	Homo sapiens	S-adenosyl-L-homocysteine	3.3	0.012	280	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C113S, S-adenosyl-L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C195D	Homo sapiens	adenosine	0.69	0.001	690	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C195D, adenosine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C195D	Homo sapiens	L-homocysteine	0.67	0.0653	10	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C195D, L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C195D	Homo sapiens	S-adenosyl-L-homocysteine	0.27	0.0041	70	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C195D, S-adenosyl-L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C195S	Homo sapiens	adenosine	1.1	0.0012	910	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C195S, adenosine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C195S	Homo sapiens	L-homocysteine	1.2	0.0788	15	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C195S, L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C195S	Homo sapiens	S-adenosyl-L-homocysteine	0.44	0.0027	160	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C195S, S-adenosyl-L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C421D	Homo sapiens	adenosine	9.1	0.0019	4.8 × 10³	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C421D, adenosine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C421D	Homo sapiens	L-homocysteine	8.9	0.0949	93	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C421D, L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C421D	Homo sapiens	S-adenosyl-L-homocysteine	3.1	0.0118	260	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C421D, S-adenosyl-L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C421S	Homo sapiens	adenosine	9.5	0.0016	5.9 × 10³	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C421S, adenosine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C421S	Homo sapiens	L-homocysteine	9.1	0.0836	100	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C421S, L-homocysteine
S-adenosylhomocysteine hydrolase (AdoHcy hydrolase)variant C421S	Homo sapiens	S-adenosyl-L-homocysteine	3.8	0.0106	360	pH 7.2, 37 °C	PMID 8910410	Open record: S-adenosylhomocysteine hydrolase (AdoHcy hydrolase) variant C421S, S-adenosyl-L-homocysteine
S-adenosylhomocysteine hydrolase (PfAdoHcyHD)	Pyrococcus furiosus	adenosine	—	0.0048	—	pH 7.4, 80 °C	PMID 15645450	Open record: S-adenosylhomocysteine hydrolase (PfAdoHcyHD), adenosine
S-adenosylhomocysteine hydrolase (PfAdoHcyHD)	Pyrococcus furiosus	L-homocysteine	—	0.14	—	pH 7.4, 80 °C	PMID 15645450	Open record: S-adenosylhomocysteine hydrolase (PfAdoHcyHD), L-homocysteine
S-adenosylhomocysteine hydrolase (PfAdoHcyHD)	Pyrococcus furiosus	S-adenosyl-L-homocysteine	—	0.014	—	80 °C	PMID 15645450	Open record: S-adenosylhomocysteine hydrolase (PfAdoHcyHD), S-adenosyl-L-homocysteine
Tm0172	Thermotoga maritima	S-adenosyl-L-homocysteine	0.004	0.021	0.11	30 °C	PMID 17603473	Open record: Tm0172, S-adenosyl-L-homocysteine
Tm0172	Thermotoga maritima	S-inosyl-L-homocysteine	0.0023	0.14	0.028	30 °C	PMID 17603473	Open record: Tm0172, S-inosyl-L-homocysteine