EC 3.4.17.18: carboxypeptidase T
HydrolasesOpen in Browse
CatLog read 28 records for EC 3.4.17.18 from 2 papers, for 1 organism. Names in these papers: carboxypeptidase T.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 11 records for EC 3.4.17.18 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.17.18 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Structural principles of the broad substrate specificity of Thermoactinomyces vulgaris carboxypeptidase T--role of amino acid residues at positions 260 and 262 | Thermoactinomyces vulgaris | 14 |
| Structural insights into the broad substrate specificity of carboxypeptidase T from Thermoactinomyces vulgaris | Thermoactinomyces vulgaris | 14 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| carboxypeptidase T | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-arginine | 3.64 | 0.69 | 5.28 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T, N-benzyloxycarbonyl-alanyl-alanyl-arginine |
| carboxypeptidase T | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-leucine | 4.67 | 0.04 | 116 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T, N-benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant D260G | Thermoactinomyces vulgaris | 2,4-dinitrophenyl-alanyl-alanyl-arginine | — | — | 0.346 | pH 7.5, 37 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G, 2,4-dinitrophenyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant D260G | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-glutamic acid | 7.2 | 0.18 | 40 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G, benzyloxycarbonyl-alanyl-alanyl-glutamic acid |
| carboxypeptidase Tvariant D260G | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-leucine | 4.1 | 0.016 | 282 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G, benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant D260G/T262I | Thermoactinomyces vulgaris | 2,4-dinitrophenyl-alanyl-alanyl-arginine | — | — | 0.132 | pH 7.5, 37 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G/T262I, 2,4-dinitrophenyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant D260G/T262I | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-glutamic acid | 8.5 | 0.3 | 28 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G/T262I, benzyloxycarbonyl-alanyl-alanyl-glutamic acid |
| carboxypeptidase Tvariant D260G/T262I | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-leucine | 5.2 | 0.03 | 184 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G/T262I, benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant D260G/T262K | Thermoactinomyces vulgaris | 2,4-dinitrophenyl-alanyl-alanyl-arginine | 0.04 | 2.8 | 0.0168 | pH 7.5, 37 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G/T262K, 2,4-dinitrophenyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant D260G/T262K | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-glutamic acid | 11.5 | 0.65 | 17.8 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G/T262K, benzyloxycarbonyl-alanyl-alanyl-glutamic acid |
| carboxypeptidase Tvariant D260G/T262K | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-leucine | 1.6 | 0.033 | 55 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G/T262K, benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant D260G/T262R | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-glutamic acid | 23.6 | 0.8 | 29.6 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G/T262R, benzyloxycarbonyl-alanyl-alanyl-glutamic acid |
| carboxypeptidase Tvariant D260G/T262R | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-leucine | 5.6 | 0.45 | 12.5 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant D260G/T262R, benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant D260N | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-arginine | 0.59 | 0.87 | 0.68 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant D260N, N-benzyloxycarbonyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant D260N | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-leucine | 1.14 | 0.053 | 21.5 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant D260N, N-benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant D263N | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-arginine | 1.14 | 1.35 | 0.84 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant D263N, N-benzyloxycarbonyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant D263N | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-leucine | 9.66 | 0.087 | 111 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant D263N, N-benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant G215S/A251G/T257A/D260G/T262D + Thr inserted between Asp253 and Leu254 (CPT6) | Thermoactinomyces vulgaris | 2,4-dinitrophenyl-alanyl-alanyl-arginine | — | — | 0.142 | pH 7.5, 37 °C | PMID 18515300 | Open record: carboxypeptidase T variant G215S/A251G/T257A/D260G/T262D + Thr inserted between Asp253 and Leu254 (CPT6), 2,4-dinitrophenyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant G215S/A251G/T257A/D260G/T262D + Thr inserted between Asp253 and Leu254 (CPT6) | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-glutamic acid | — | — | 0.0375 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant G215S/A251G/T257A/D260G/T262D + Thr inserted between Asp253 and Leu254 (CPT6), benzyloxycarbonyl-alanyl-alanyl-glutamic acid |
| carboxypeptidase Tvariant G215S/A251G/T257A/D260G/T262D + Thr inserted between Asp253 and Leu254 (CPT6) | Thermoactinomyces vulgaris | benzyloxycarbonyl-alanyl-alanyl-leucine | 7.1 | 0.75 | 9.7 | pH 7.5, 25 °C | PMID 18515300 | Open record: carboxypeptidase T variant G215S/A251G/T257A/D260G/T262D + Thr inserted between Asp253 and Leu254 (CPT6), benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant L211Q | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-arginine | 18.97 | 0.52 | 36 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant L211Q, N-benzyloxycarbonyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant L211Q | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-leucine | 4.62 | 0.43 | 11 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant L211Q, N-benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant L254S | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-arginine | 4.61 | 0.27 | 17.4 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant L254S, N-benzyloxycarbonyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant L254S | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-leucine | 6.56 | 0.27 | 24.3 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant L254S, N-benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant T257D | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-arginine | 9.45 | 0.67 | 14.1 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant T257D, N-benzyloxycarbonyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant T257D | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-leucine | 5 | 0.31 | 15.9 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant T257D, N-benzyloxycarbonyl-alanyl-alanyl-leucine |
| carboxypeptidase Tvariant T262G | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-arginine | 12.76 | 0.59 | 21.7 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant T262G, N-benzyloxycarbonyl-alanyl-alanyl-arginine |
| carboxypeptidase Tvariant T262G | Thermoactinomyces vulgaris | N-benzyloxycarbonyl-alanyl-alanyl-leucine | 9.9 | 0.06 | 155 | pH 7.5, 25 °C | PMID 25619204 | Open record: carboxypeptidase T variant T262G, N-benzyloxycarbonyl-alanyl-alanyl-leucine |