EC 3.4.21.26: prolyl oligopeptidase
HydrolasesOpen in Browse
CatLog read 28 records for EC 3.4.21.26 from 3 papers, for 3 organisms. Names in these papers: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase), prolyl oligopeptidase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 46 records for EC 3.4.21.26 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.4.21.26 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Methionine residues lining the substrate pathway in prolyl oligopeptidase from Pleurotus eryngii play an important role in substrate recognition | Pleurotus eryngii | 16 |
| Kinetic and mechanistic studies of prolyl oligopeptidase from the hyperthermophile Pyrococcus furiosus | Pyrococcus furiosus | 11 |
| Selective neurotensin-derived internally quenched fluorogenic substrates for neurolysin (EC 3.4.24.16): comparison with thimet oligopeptidase (EC 3.4.24.15) and neprilysin (EC 3.4.24.11) | Sus scrofa | 1 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M142Q/M203Q/M570Q/M620Q | Pleurotus eryngii | L-leucine p-nitroanilide | 75 | 0.68 | 110 | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M142Q/M203Q/M570Q/M620Q, L-leucine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M142Q/M203Q/M570Q/M620Q | Pleurotus eryngii | L-phenylalanine p-nitroanilide | 550 | 0.12 | 4.6 × 10³ | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M142Q/M203Q/M570Q/M620Q, L-phenylalanine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M203Q | Pleurotus eryngii | L-leucine p-nitroanilide | 210 | 0.3 | 720 | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M203Q, L-leucine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M203Q | Pleurotus eryngii | L-phenylalanine p-nitroanilide | 1.9 × 10³ | 0.18 | 1 × 10⁴ | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M203Q, L-phenylalanine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M203Q/M570Q | Pleurotus eryngii | L-leucine p-nitroanilide | 58 | 0.62 | 94 | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M203Q/M570Q, L-leucine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M203Q/M570Q | Pleurotus eryngii | L-phenylalanine p-nitroanilide | 1.2 × 10³ | 0.34 | 3.5 × 10³ | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M203Q/M570Q, L-phenylalanine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570A | Pleurotus eryngii | L-leucine p-nitroanilide | 210 | 0.98 | 220 | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570A, L-leucine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570A | Pleurotus eryngii | L-phenylalanine p-nitroanilide | 1.1 × 10³ | 0.16 | 6.8 × 10³ | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570A, L-phenylalanine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570E | Pleurotus eryngii | L-leucine p-nitroanilide | 240 | 1.1 | 220 | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570E, L-leucine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570E | Pleurotus eryngii | L-phenylalanine p-nitroanilide | 950 | 0.11 | 8.3 × 10³ | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570E, L-phenylalanine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570F | Pleurotus eryngii | L-leucine p-nitroanilide | 26 | 0.73 | 35 | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570F, L-leucine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570F | Pleurotus eryngii | L-phenylalanine p-nitroanilide | 1.1 × 10³ | 0.64 | 1.8 × 10³ | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570F, L-phenylalanine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570K | Pleurotus eryngii | L-leucine p-nitroanilide | 4.9 | 0.86 | 5.7 | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570K, L-leucine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570K | Pleurotus eryngii | L-phenylalanine p-nitroanilide | 920 | 0.82 | 1.1 × 10³ | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570K, L-phenylalanine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570Q | Pleurotus eryngii | L-leucine p-nitroanilide | 180 | 0.89 | 200 | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570Q, L-leucine p-nitroanilide |
| eryngase (S9 prolyl oligopeptidase family serine aminopeptidase)variant M570Q | Pleurotus eryngii | L-phenylalanine p-nitroanilide | 710 | 0.18 | 3.9 × 10³ | pH 8 | PMID 29623768 | Open record: eryngase (S9 prolyl oligopeptidase family serine aminopeptidase) variant M570Q, L-phenylalanine p-nitroanilide |
| prolyl oligopeptidase | Pyrococcus furiosus | benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide | 16.9 | 0.16 | 106 | pH 7.5, 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide |
| prolyl oligopeptidase | Pyrococcus furiosus | benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide0.1 M NaCl | 15.8 | — | 79.6 | 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide |
| prolyl oligopeptidase | Pyrococcus furiosus | benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide0.1 M NaCl | 18.1 | — | 144.6 | 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide |
| prolyl oligopeptidase | Pyrococcus furiosus | benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide0.8 M NaCl | 15.9 | — | 147 | 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide |
| prolyl oligopeptidase | Pyrococcus furiosus | benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide0.8 M NaCl | 18.6 | — | 325 | 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, benzyloxycarbonyl-glycyl-prolyl-p-nitroanilide |
| prolyl oligopeptidase | Pyrococcus furiosus | H-Ala-Pro-pNA | 0.079 | 0.0194 | 4.08 | pH 7.5, 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, H-Ala-Pro-pNA |
| prolyl oligopeptidase | Pyrococcus furiosus | H-Arg-Pro-pNA | 0.03 | 0.0229 | 1.31 | pH 7.5, 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, H-Arg-Pro-pNA |
| prolyl oligopeptidase | Pyrococcus furiosus | H-Asp-Pro-pNA | 0.073 | 0.04 | 1.82 | pH 7.5, 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, H-Asp-Pro-pNA |
| prolyl oligopeptidase | Pyrococcus furiosus | H-Gly-Pro-pNA | 0.06 | 0.0207 | 2.9 | pH 7.5, 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, H-Gly-Pro-pNA |
| prolyl oligopeptidase | Pyrococcus furiosus | Z-Ala-Ala-pNA | 2.5 | 0.043 | 57.6 | pH 7.5, 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, Z-Ala-Ala-pNA |
| prolyl oligopeptidase | Pyrococcus furiosus | Z-Ala-Pro-pNA | 17.9 | 0.0437 | 410 | pH 7.5, 85 °C | PMID 11278687 | Open record: prolyl oligopeptidase, Z-Ala-Pro-pNA |
| prolyl oligopeptidase | Sus scrofa | ortho-aminobenzoyl-Asn-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine | 0.03 | 4.4 × 10⁻⁴ | 68 | pH 7.5, 37 °C | PMID 11355859 | Open record: prolyl oligopeptidase, ortho-aminobenzoyl-Asn-Lys-Pro-Arg-Arg-Pro-Gln-N-(2,4-dinitrophenyl)ethylenediamine |