EC 3.5.1.19: nicotinamidase
HydrolasesOpen in Browse
CatLog read 71 records for EC 3.5.1.19 from 4 papers, for 3 organisms. Names in these papers: nicotinamidase (UbNic), nicotinamidase (OiNIC), nicotinamidase (Pnc1), nicotinamide deamidase (PncA).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 32 records for EC 3.5.1.19 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.5.1.19 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Biochemical characterization of a new nicotinamidase from an unclassified bacterium thriving in a geothermal water stream microbial mat community | — | 27 |
| Biochemical and mutational analysis of a novel nicotinamidase from Oceanobacillus iheyensis HTE831 | Oceanobacillus iheyensis | 26 |
| Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae | Saccharomyces cerevisiae | 17 |
| Genomics-driven reconstruction of acinetobacter NAD metabolism: insights for antibacterial target selection | Acinetobacter baylyi | 1 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| nicotinamidase (OiNIC) | Oceanobacillus iheyensis | 5-methylnicotinamide | 5.1 | 0.68 | 7.5 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC), 5-methylnicotinamide |
| nicotinamidase (OiNIC) | Oceanobacillus iheyensis | ethyl nicotinate | 0.1 | 1.02 | 0.1 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC), ethyl nicotinate |
| nicotinamidase (OiNIC) | Oceanobacillus iheyensis | methyl nicotinate | 0.32 | 1.03 | 0.31 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC), methyl nicotinate |
| nicotinamidase (OiNIC) | Oceanobacillus iheyensis | nicotinamide | 11.65 | 0.26 | 43.48 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC), nicotinamide |
| nicotinamidase (OiNIC) | Oceanobacillus iheyensis | pyrazinamide | 2.6 | 0.81 | 3.2 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC), pyrazinamide |
| nicotinamidase (OiNIC)variant C133A | Oceanobacillus iheyensis | 5-methylnicotinamide | 7.09 | 0.64 | 11.07 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant C133A, 5-methylnicotinamide |
| nicotinamidase (OiNIC)variant C133A | Oceanobacillus iheyensis | ethyl nicotinate | 0.14 | 0.34 | 0.41 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant C133A, ethyl nicotinate |
| nicotinamidase (OiNIC)variant C133A | Oceanobacillus iheyensis | methyl nicotinate | 1.02 | 0.89 | 1.14 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant C133A, methyl nicotinate |
| nicotinamidase (OiNIC)variant C133A | Oceanobacillus iheyensis | nicotinamide | 13.6 | 0.4 | 34 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant C133A, nicotinamide |
| nicotinamidase (OiNIC)variant C133A | Oceanobacillus iheyensis | pyrazinamide | 3.31 | 0.36 | 9.19 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant C133A, pyrazinamide |
| nicotinamidase (OiNIC)variant C133A/F68W | Oceanobacillus iheyensis | nicotinamide | 9.82 | 0.19 | 52.8 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant C133A/F68W, nicotinamide |
| nicotinamidase (OiNIC)variant C133A/F68W | Oceanobacillus iheyensis | pyrazinamide | 5.21 | 0.83 | 6.28 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant C133A/F68W, pyrazinamide |
| nicotinamidase (OiNIC)variant E65H | Oceanobacillus iheyensis | nicotinamide | 5.63 | 0.13 | 42.65 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant E65H, nicotinamide |
| nicotinamidase (OiNIC)variant E65H | Oceanobacillus iheyensis | pyrazinamide | 0.43 | 0.82 | 0.52 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant E65H, pyrazinamide |
| nicotinamidase (OiNIC)variant F68W | Oceanobacillus iheyensis | nicotinamide | 8.79 | 0.17 | 52.01 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant F68W, nicotinamide |
| nicotinamidase (OiNIC)variant F68W | Oceanobacillus iheyensis | pyrazinamide | 3.94 | 0.5 | 7.9 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant F68W, pyrazinamide |
| nicotinamidase (OiNIC)variant Q96A | Oceanobacillus iheyensis | 5-methylnicotinamide | 15.9 | 0.55 | 29.04 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96A, 5-methylnicotinamide |
| nicotinamidase (OiNIC)variant Q96A | Oceanobacillus iheyensis | ethyl nicotinate | 0.19 | 1.43 | 0.13 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96A, ethyl nicotinate |
| nicotinamidase (OiNIC)variant Q96A | Oceanobacillus iheyensis | methyl nicotinate | 0.6 | 0.56 | 1.17 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96A, methyl nicotinate |
| nicotinamidase (OiNIC)variant Q96A | Oceanobacillus iheyensis | nicotinamide | 16.05 | 0.36 | 44.59 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96A, nicotinamide |
| nicotinamidase (OiNIC)variant Q96A | Oceanobacillus iheyensis | pyrazinamide | 1.61 | 1.2 | 1.34 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96A, pyrazinamide |
| nicotinamidase (OiNIC)variant Q96K | Oceanobacillus iheyensis | 5-methylnicotinamide | 2.16 | 0.62 | 3.4 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96K, 5-methylnicotinamide |
| nicotinamidase (OiNIC)variant Q96K | Oceanobacillus iheyensis | ethyl nicotinate | 0.05 | 1.11 | 0.05 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96K, ethyl nicotinate |
| nicotinamidase (OiNIC)variant Q96K | Oceanobacillus iheyensis | methyl nicotinate | 0.17 | 0.44 | 0.38 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96K, methyl nicotinate |
| nicotinamidase (OiNIC)variant Q96K | Oceanobacillus iheyensis | nicotinamide | 2.37 | 0.57 | 4.15 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96K, nicotinamide |
| nicotinamidase (OiNIC)variant Q96K | Oceanobacillus iheyensis | pyrazinamide | 0.45 | 1.15 | 0.39 | pH 7.3, 37 °C | PMID 23451075 | Open record: nicotinamidase (OiNIC) variant Q96K, pyrazinamide |
| nicotinamidase (Pnc1) | Saccharomyces cerevisiae | 1-methylnicotinamide | — | — | 0.0086 | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1), 1-methylnicotinamide |
| nicotinamidase (Pnc1) | Saccharomyces cerevisiae | 5-methylnicotinamide | 1.75 | 0.061 | 29 | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1), 5-methylnicotinamide |
| nicotinamidase (Pnc1) | Saccharomyces cerevisiae | benzamide | 0.0088 | 0.025 | 0.35 | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1), benzamide |
| nicotinamidase (Pnc1) | Saccharomyces cerevisiae | nicotinamide | 0.69 | 0.0096 | 72 | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1), nicotinamide |
| nicotinamidase (Pnc1) | Saccharomyces cerevisiae | nicotinamidelow-pH | 0.45 | — | — | 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1), nicotinamide |
| nicotinamidase (Pnc1) | Saccharomyces cerevisiae | nicotinamidehigh-pH | 1.87 | — | — | 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1), nicotinamide |
| nicotinamidase (Pnc1) | Saccharomyces cerevisiae | pyrazinamide | 2.56 | 0.157 | 16 | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1), pyrazinamide |
| nicotinamidase (Pnc1) | Saccharomyces cerevisiae | thionicotinamide | — | — | 0.05 | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1), thionicotinamide |
| nicotinamidase (Pnc1)variant D51A | Saccharomyces cerevisiae | nicotinamide | 0.02 | — | — | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant D51A, nicotinamide |
| nicotinamidase (Pnc1)variant D51N | Saccharomyces cerevisiae | nicotinamide | 0.064 | — | — | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant D51N, nicotinamide |
| nicotinamidase (Pnc1)variant D8A | Saccharomyces cerevisiae | nicotinamide | 9 × 10⁻⁴ | — | — | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant D8A, nicotinamide |
| nicotinamidase (Pnc1)variant D8E | Saccharomyces cerevisiae | nicotinamide | 0.007 | — | — | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant D8E, nicotinamide |
| nicotinamidase (Pnc1)variant D8N | Saccharomyces cerevisiae | nicotinamide | 6 × 10⁻⁴ | — | — | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant D8N, nicotinamide |
| nicotinamidase (Pnc1)variant H53A | Saccharomyces cerevisiae | nicotinamide | 0.014 | 0.0065 | 2.2 | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant H53A, nicotinamide |
| nicotinamidase (Pnc1)variant H94A | Saccharomyces cerevisiae | nicotinamide | 0.02 | — | — | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant H94A, nicotinamide |
| nicotinamidase (Pnc1)variant K122A | Saccharomyces cerevisiae | nicotinamide | 0.044 | — | — | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant K122A, nicotinamide |
| nicotinamidase (Pnc1)variant K122R | Saccharomyces cerevisiae | nicotinamide | 9 × 10⁻⁴ | — | — | pH 7.5, 25 °C | PMID 22229411 | Open record: nicotinamidase (Pnc1) variant K122R, nicotinamide |
| nicotinamidase (UbNic) | — | 5-methyl-nicotinamide | 43.7 | 1.09 | 40.1 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic), 5-methyl-nicotinamide |
| nicotinamidase (UbNic) | — | Ethylnicotinate | 3.7 | 1.31 | 2.8 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic), Ethylnicotinate |
| nicotinamidase (UbNic) | — | Methylnicotinate | 54.5 | 1.08 | 50.5 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic), Methylnicotinate |
| nicotinamidase (UbNic) | — | nicotinamide | 22.7 | 0.12 | 189.2 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic), nicotinamide |
| nicotinamidase (UbNic) | — | nicotinamide | 41.7 | 0.004 | 10,425 | pH 7.3, 60 °C | PMID 28750065 | Open record: nicotinamidase (UbNic), nicotinamide |
| nicotinamidase (UbNic) | — | pyrazinamide | 18.7 | 0.33 | 56.7 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic), pyrazinamide |
| nicotinamidase (UbNic) | — | pyrazinamide | 105.0 | 0.095 | 1105 | pH 7.3, 60 °C | PMID 28750065 | Open record: nicotinamidase (UbNic), pyrazinamide |
| nicotinamidase (UbNic)variant A151C | — | 5-methyl-nicotinamide | 9.6 | 0.21 | 45.7 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant A151C, 5-methyl-nicotinamide |
| nicotinamidase (UbNic)variant A151C | — | Ethylnicotinate | 0.3 | 0.89 | 0.3 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant A151C, Ethylnicotinate |
| nicotinamidase (UbNic)variant A151C | — | Methylnicotinate | 4.3 | 0.21 | 20.5 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant A151C, Methylnicotinate |
| nicotinamidase (UbNic)variant A151C | — | nicotinamide | 5.1 | 0.1 | 51 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant A151C, nicotinamide |
| nicotinamidase (UbNic)variant A151C | — | pyrazinamide | 7.5 | 0.22 | 34.1 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant A151C, pyrazinamide |
| nicotinamidase (UbNic)variant H75E | — | 5-methyl-nicotinamide | 4.9 | 0.14 | 35 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75E, 5-methyl-nicotinamide |
| nicotinamidase (UbNic)variant H75E | — | Ethylnicotinate | 0.1 | 0.46 | 0.2 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75E, Ethylnicotinate |
| nicotinamidase (UbNic)variant H75E | — | Methylnicotinate | 5.8 | 0.41 | 14.1 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75E, Methylnicotinate |
| nicotinamidase (UbNic)variant H75E | — | nicotinamide | 10.2 | 0.15 | 68 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75E, nicotinamide |
| nicotinamidase (UbNic)variant H75E | — | pyrazinamide | 3.5 | 0.67 | 5.2 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75E, pyrazinamide |
| nicotinamidase (UbNic)variant H75S | — | 5-methyl-nicotinamide | 12.4 | 0.23 | 53.9 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75S, 5-methyl-nicotinamide |
| nicotinamidase (UbNic)variant H75S | — | Ethylnicotinate | 0.2 | 1.21 | 0.2 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75S, Ethylnicotinate |
| nicotinamidase (UbNic)variant H75S | — | Methylnicotinate | 1.9 | 0.68 | 2.8 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75S, Methylnicotinate |
| nicotinamidase (UbNic)variant H75S | — | nicotinamide | 12.5 | 0.23 | 54.3 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75S, nicotinamide |
| nicotinamidase (UbNic)variant H75S | — | pyrazinamide | 1.3 | 0.59 | 2.2 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant H75S, pyrazinamide |
| nicotinamidase (UbNic)variant W83F | — | 5-methyl-nicotinamide | 13.7 | 0.74 | 18.5 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant W83F, 5-methyl-nicotinamide |
| nicotinamidase (UbNic)variant W83F | — | Ethylnicotinate | 0.2 | 3.84 | 0.1 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant W83F, Ethylnicotinate |
| nicotinamidase (UbNic)variant W83F | — | Methylnicotinate | 4.9 | 3.59 | 1.4 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant W83F, Methylnicotinate |
| nicotinamidase (UbNic)variant W83F | — | nicotinamide | 15.5 | 0.39 | 39.7 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant W83F, nicotinamide |
| nicotinamidase (UbNic)variant W83F | — | pyrazinamide | 3.1 | 2.89 | 1.1 | pH 7.3, 37 °C | PMID 28750065 | Open record: nicotinamidase (UbNic) variant W83F, pyrazinamide |
| nicotinamide deamidase (PncA) | Acinetobacter baylyi | nicotinamide | 0.69 | 0.0025 | 280 | pH 7.5 | PMID 20926389 | Open record: nicotinamide deamidase (PncA), nicotinamide |