CatLogenzyme kinetics catalog

EC 4.1.1.17: ornithine decarboxylase

LyasesOpen in Browse

CatLog read 70 records for EC 4.1.1.17 from 9 papers, for 18 organisms. Names in these papers: ornithine decarboxylase (ODC), ornithine decarboxylase (ODC, SpeC), ornithine decarboxylase, putative ornithine decarboxylase (ODC) and 9 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 68 records for EC 4.1.1.17 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.1.1.17 in Browse.

Papers

PaperOrganismsRecords
Rational design of ornithine decarboxylase with high catalytic activity for the production of putrescineEscherichia coli13
Acidic residues important for substrate binding and cofactor reactivity in eukaryotic ornithine decarboxylase identified by alanine scanning mutagenesisLeishmania donovani, Mus musculus and 1 more13
Identification of essential active-site residues in ornithine decarboxylase of Nicotiana glutinosa decarboxylating both L-ornithine and L-lysineNicotiana glutinosa9
Evidence of two functionally distinct ornithine decarboxylation systems in lactic acid bacteriaLactobacillus brevis, Lactobacillus casei and 2 more9
Formation of functional cross-species heterodimers of ornithine decarboxylaseLeishmania donovani, Mus musculus and 2 more8
Paramecium bursaria chlorella virus-1 encodes an unusual arginine decarboxylase that is a close homolog of eukaryotic ornithine decarboxylasesParamecium bursaria chlorella virus 1, Trypanosoma brucei6
Lysine decarboxylase catalyzes the first step of quinolizidine alkaloid biosynthesis and coevolved with alkaloid production in leguminosaeEchinosophora koreensis, Lupinus angustifolius and 1 more6
Phylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylasesNitrosomonas europaea, Vibrio vulnificus4
Mutually exclusive pathways for biosynthesis of polyamine homospermidine dependent on putrescine or agmatineRhodopila globiformis, Rhodothalassium salexigens2

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
alanine racemase-fold ornithine decarboxylase homolog, neofunctionalized arginine decarboxylase (AR-fold ODC/ADC)Rhodopila globiformisL-arginine4.992.22.325 °CPMID 42665092Open
alanine racemase-fold ornithine decarboxylase homolog, neofunctionalized arginine decarboxylase (AR-fold ODC/ADC)Rhodothalassium salexigensL-arginine5.621.693.325 °CPMID 42665092Open
Ek-L/ODC (lysine/ornithine decarboxylase)Echinosophora koreensisL-ornithine0.731.320.454pH 7.5, 37 °CPMID 22415272Open
La-L/ODC (lysine/ornithine decarboxylase)Lupinus angustifoliusL-ornithine0.911.050.859pH 7.5, 37 °CPMID 22415272Open
La-L/ODC (lysine/ornithine decarboxylase)variant F344HLupinus angustifoliusL-ornithine2.291.531.496pH 7.5, 37 °CPMID 22415272Open
La-L/ODC (lysine/ornithine decarboxylase)variant F344YLupinus angustifoliusL-ornithine0.41.590.253pH 7.5, 37 °CPMID 22415272Open
La-L/ODC (lysine/ornithine decarboxylase)variant M341LLupinus angustifoliusL-ornithine0.291.040.279pH 7.5, 37 °CPMID 22415272Open
lysine/ornithine decarboxylase (VvL/ODC)Vibrio vulnificusL-lysine245.84.1pH 8, 37 °CPMID 17626020Open
lysine/ornithine decarboxylase (VvL/ODC)Vibrio vulnificusL-ornithine291.717pH 8, 37 °CPMID 17626020Open
ornithine decarboxylaseLeishmania donovaniornithine7.70.4219pH 8, 37 °CPMID 7947774Open
ornithine decarboxylasevariant K69A:C360A heterodimer (ld-K69A:ld-C360A)Leishmania donovaniornithine1.20.353.5pH 8, 37 °CPMID 7947774Open
ornithine decarboxylaseMus musculusornithine7.80.0987pH 8, 37 °CPMID 7947774Open
ornithine decarboxylasevariant K69A:C360A heterodimer (m-K69A:m-C360A)Mus musculusornithine9.20.051180pH 8, 37 °CPMID 7947774Open
ornithine decarboxylaseNitrosomonas europaeaL-lysine0.22180.012pH 8, 37 °CPMID 17626020Open
ornithine decarboxylaseNitrosomonas europaeaL-ornithine3.52.31.5pH 8, 37 °CPMID 17626020Open
ornithine decarboxylaseTrypanosoma bruceiornithine7.40.1841pH 8, 37 °CPMID 7947774Open
ornithine decarboxylasevariant K69A:C360A heterodimer (tb-K69A:tb-C360A)Trypanosoma bruceiornithine7.80.2433pH 8, 37 °CPMID 7947774Open
ornithine decarboxylase (mouse : Trypanosoma brucei cross-species heterodimer)variant K69A:C360A cross-species heterodimer (m-K69A:tb-C360A)mouse / Trypanosoma bruceiornithine9.70.2637pH 8, 37 °CPMID 7947774Open
ornithine decarboxylase (mouse : Trypanosoma brucei cross-species heterodimer)variant K69A:C360A cross-species heterodimer (tb-K69A:m-C360A)mouse / Trypanosoma bruceiornithine9.10.049190pH 8, 37 °CPMID 7947774Open
ornithine decarboxylase (ODC)Leishmania donovaniArginine2.31030.022pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)Leishmania donovaniLysine0.31180.018pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)Mus musculusArginine3.5410.085pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)Mus musculusLysine1.85.20.35pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)Nicotiana glutinosaL-lysine0.2361.5920.148pH 6.8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)Nicotiana glutinosaL-ornithine77.780.562150pH 8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)variant C338ANicotiana glutinosaL-lysine0.2041.1140.1832pH 6.8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)variant C338ANicotiana glutinosaL-ornithine10.544.5591.508pH 8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)variant C377ANicotiana glutinosaL-ornithine3.370.3980.8471pH 8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)variant C96ANicotiana glutinosaL-lysine0.2071.0940.1888pH 6.8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)variant C96ANicotiana glutinosaL-ornithine32.730.81241pH 8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)variant K95ANicotiana glutinosaL-lysine0.0834.9830.07596pH 6.8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)variant K95ANicotiana glutinosaL-ornithine0.7417.520.4199pH 8, 37 °CPMID 11736657Open
ornithine decarboxylase (ODC)Trypanosoma bruceiArginine1350.029pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)Trypanosoma bruceiLysine2.2210.1pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)variant D233ATrypanosoma bruceiornithine0.0580.670.087pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)variant D361ATrypanosoma bruceiornithine3.14500.0067pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)variant D361ETrypanosoma bruceiornithine0.29310.0094pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)variant D88ATrypanosoma bruceiornithine0.0434.40.0098pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)variant E274ATrypanosoma bruceiornithinesaturating PLP (20 µM)0.152.80.054pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)variant E274ATrypanosoma bruceiornithinesaturating Orn (50 mM)6——pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC)variant E94ATrypanosoma bruceiornithine0.180.460.39pH 8, 37 °CPMID 7744828Open
ornithine decarboxylase (ODC, SpeC)Escherichia coliL-ornithine3.43.31PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant E165AEscherichia coliL-ornithine4.82.42PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant E165GEscherichia coliL-ornithine5.631.9PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant E165SEscherichia coliL-ornithine10.11.95.2PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant E165TEscherichia coliL-ornithine24.80.737PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant E165VEscherichia coliL-ornithine10.91.47.6PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant I163AEscherichia coliL-ornithine3.61.52.4PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant I163GEscherichia coliL-ornithine4.21.72.5PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant I163SEscherichia coliL-ornithine7.41.54.8PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant I163TEscherichia coliL-ornithine10.10.618PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant I163T/E165TEscherichia coliL-ornithine38.50.664PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant I163VEscherichia coliL-ornithine4.41.33.5PMID 24706212Open
ornithine decarboxylase (ODC, SpeC)variant I163V/E165VEscherichia coliL-ornithine25.71.123PMID 24706212Open
ornithine decarboxylase (TbODC)variant D332ETrypanosoma bruceiL-arginine0.04340.001237 °CPMID 15190062Open
ornithine decarboxylase (TbODC)variant D332ETrypanosoma bruceiL-ornithine106.11.637 °CPMID 15190062Open
PBCV-1 DC (arginine decarboxylase, eukaryotic ODC homolog)Paramecium bursaria chlorella virus 1L-ornithine101800.06pH 8.2, 37 °CPMID 15190062Open
PBCV-1 DC (arginine decarboxylase, eukaryotic ODC homolog)Paramecium bursaria chlorella virus 1L-ornithine14460.3pH 9, 42 °CPMID 15190062Open
PBCV-1 DC (arginine decarboxylase, eukaryotic ODC homolog)variant T142AParamecium bursaria chlorella virus 1L-ornithine0.91360.007437 °CPMID 15190062Open
PBCV-1 DC (arginine decarboxylase, eukaryotic ODC homolog)variant T142A/E296DParamecium bursaria chlorella virus 1L-ornithine0.021451.4 × 10⁻⁴37 °CPMID 15190062Open
putative arginine/lysine/ornithine decarboxylaseLactobacillus caseiL-2,4-diaminobutyric acid0.053.90.012pH 7.5, 37 °CPMID 22247134Open
putative arginine/lysine/ornithine decarboxylaseLactobacillus gasseriL-2,4-diaminobutyric acid0.3512.10.03pH 7.5, 37 °CPMID 22247134Open
putative arginine/lysine/ornithine decarboxylaseLactobacillus gasseriornithine0.1387.20.02pH 7.5, 37 °CPMID 22247134Open
putative ornithine decarboxylase (ODC)Lactobacillus brevisL-2,4-diaminobutyric acid0.4511.20.04pH 5.5, 37 °CPMID 22247134Open
putative ornithine decarboxylase (ODC)Lactobacillus brevisL-lysine0.577.20.077pH 5.5, 37 °CPMID 22247134Open
putative ornithine decarboxylase (ODC)Lactobacillus brevisornithine4.8314.7pH 5.5, 37 °CPMID 22247134Open
putative ornithine decarboxylase (ODC)Oenococcus oeniL-2,4-diaminobutyric acid0.0454.90.0083pH 5.5, 37 °CPMID 22247134Open
putative ornithine decarboxylase (ODC)Oenococcus oeniL-lysine0.09350.018pH 5.5, 37 °CPMID 22247134Open
putative ornithine decarboxylase (ODC)Oenococcus oeniornithine6.930.79.2pH 5.5, 37 °CPMID 22247134Open
Sf-L/ODC (lysine/ornithine decarboxylase)Sophora flavescensL-ornithine1.161.530.755pH 7.5, 37 °CPMID 22415272Open