EC 4.1.1.72: branched-chain-2-oxoacid decarboxylase
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CatLog read 55 records for EC 4.1.1.72 from 2 papers, for 2 organisms. Names in these papers: phenylpyruvate decarboxylase (ScPPDC), KdcA (branched-chain alpha-keto acid decarboxylase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 17 records for EC 4.1.1.72 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.1.1.72 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Characterization of a thiamin diphosphate-dependent phenylpyruvate decarboxylase from Saccharomyces cerevisiae | Saccharomyces cerevisiae | 41 |
| Structure-Guided Engineering of α-Keto Acid Decarboxylase for the Production of Higher Alcohols at Elevated Temperature | Lactococcus lactis | 14 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| KdcA (branched-chain alpha-keto acid decarboxylase) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 145 | 5.1 | 28 calc. | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I (1M) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 120 | 5.6 | 21 calc. | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I (1M), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290C/Q252N/D306G/E316R/F388Y/L434C (7M.D) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 69 | — | — | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290C/Q252N/D306G/E316R/F388Y/L434C (7M.D), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290C/Q252N/D306G/E316R/F388Y/L434C (7M.D) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | — | 5.2 | — | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290C/Q252N/D306G/E316R/F388Y/L434C (7M.D), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290C/Q252N/D306G/E316R/F388Y/L434C (7M.D) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 101 | — | — | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290C/Q252N/D306G/E316R/F388Y/L434C (7M.D), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290C/Q252N/D306G/E316R/F388Y/L434C (7M.D) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | — | 4.2 | — | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290C/Q252N/D306G/E316R/F388Y/L434C (7M.D), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290M (2M) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 118 | 9.3 | 13 calc. | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290M (2M), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290M/Q252N/D306G/E316R/F388Y (6M) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 149 | 14.6 | 10.2 calc. | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290M/Q252N/D306G/E316R/F388Y (6M), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290M/Q252N/D306G/E316R/F388Y/I404C (7M.B) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 5.2 | — | — | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290M/Q252N/D306G/E316R/F388Y/I404C (7M.B), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290M/Q252N/D306G/E316R/F388Y/I404C (7M.B) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | — | 2.6 | — | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290M/Q252N/D306G/E316R/F388Y/I404C (7M.B), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290M/Q252N/D306G/E316R/F388Y/I404C (7M.B) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 8.8 | — | — | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290M/Q252N/D306G/E316R/F388Y/I404C (7M.B), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290M/Q252N/D306G/E316R/F388Y/I404C (7M.B) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | — | 2.7 | — | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290M/Q252N/D306G/E316R/F388Y/I404C (7M.B), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290M/Q252N/D306G/E316R/F388Y/L434C (7M.A) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 95 | 8.6 | 11 calc. | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290M/Q252N/D306G/E316R/F388Y/L434C (7M.A), 3-methyl-2-oxobutanoic acid |
| KdcA (branched-chain alpha-keto acid decarboxylase)variant V461I/A290V/Q252N/D306G/E316R/F388Y/L434C (7M.C) | Lactococcus lactis | 3-methyl-2-oxobutanoic acid | 43 | 6.6 | 6.5 calc. | pH 6.5, 30 °C | PMID 29953730 | Open record: KdcA (branched-chain alpha-keto acid decarboxylase) variant V461I/A290V/Q252N/D306G/E316R/F388Y/L434C (7M.C), 3-methyl-2-oxobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Keto-4-phenylbutanoic acid | 1.7 | 0.09 | 19 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Keto-4-phenylbutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-ketobutanoic acid | 3.9 | 7.6 | 0.52 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketobutanoic acid | 3.9 | 7.6 | 0.51 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 8.8 | 0.69 | 13 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 8.8 | 0.48 | 18 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 5.2 | 2.1 | 2.5 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 2.8 | 1.7 | 1.6 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 3-Methyl-2-ketobutanoic acid | 19 | 8.5 | 2.2 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 3-Methyl-2-ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 3-Methyl-2-ketopentanoic acid | 11 | 3.1 | 3.5 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 3-Methyl-2-ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 4-Hydroxyphenylpyruvic acid | 11 | 0.09 | 125 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 4-Hydroxyphenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 4-Methyl-2-ketopentanoic acid | 10 | 0.9 | 11 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 4-Methyl-2-ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 4-Methylthio-2-ketobutanoic acid | 7.7 | 0.64 | 12 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 4-Methylthio-2-ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Benzoylformic acid | — | — | 0.35 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Benzoylformic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Indole-3-pyruvic acid | 5.4 | 0.03 | 200 | pH 6.5, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Indole-3-pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Indole-3-pyruvic acidkcat from a Hill fit | 5.3 | — | — | pH 6.5, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Indole-3-pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Phenylpyruvic acid | 20 | 0.1 | 200 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Phenylpyruvic acid | 20 | 0.1 | 200 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Phenylpyruvic acidkcat from a Hill fit | 22 | — | — | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Pyruvic acid | 0.34 | 9.7 | 0.035 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Pyruvic acid | 0.26 | 5.7 | 0.046 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant E545L | Saccharomyces cerevisiae | Indole-3-pyruvic acid | 0.14 | — | — | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant E545L, Indole-3-pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant E545L | Saccharomyces cerevisiae | Phenylpyruvic acid | 0.03 | — | — | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant E545L, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | 2-Ketobutanoic acid | 0.06 | 6.4 | 0.009 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, 2-Ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 3.3 | 0.55 | 6 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 2.1 | 0.63 | 3.4 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | Phenylpyruvic acid | 0.85 | 0.8 | 1.1 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | Pyruvic acid | 0.064 | 25 | 0.003 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y/M624W | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 0.41 | 1 | 0.42 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y/M624W, 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y/M624W | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 0.39 | 0.96 | 0.4 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y/M624W, 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y/M624W | Saccharomyces cerevisiae | Phenylpyruvic acid | — | — | 0.03 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y/M624W, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y/M624W | Saccharomyces cerevisiae | Pyruvic acid | — | — | 0.027 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y/M624W, Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | 2-Ketobutanoic acid | 0.04 | 5.5 | 0.007 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, 2-Ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 0.96 | 0.17 | 5.8 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 0.76 | 0.37 | 2.1 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | Phenylpyruvic acid | 1.2 | 0.18 | 6.7 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | Pyruvic acid | 0.45 | 6.4 | 0.07 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | 2-Ketobutanoic acid | 2.2 | 7 | 0.315 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, 2-Ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 1.3 | 0.46 | 2.8 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 2 | 0.54 | 3.7 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | Phenylpyruvic acid | 4.8 | 0.054 | 89 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | Pyruvic acid | 0.32 | 5.5 | 0.06 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, Pyruvic acid |