EC 4.2.1.8: mannonate dehydratase
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CatLog read 16 records for EC 4.2.1.8 from 2 papers, for 3 organisms. Names in these papers: mannonate dehydratase (EcManD), CsManD (D-mannonate dehydratase subgroup member), NaManD (D-mannonate dehydratase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 29 records for EC 4.2.1.8 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.2.1.8 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium | Escherichia coli | 8 |
| Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup | Chromohalobacter salexigens, Novosphingobium aromaticivorans | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| CsManD (D-mannonate dehydratase subgroup member) | Chromohalobacter salexigens | D-gluconate | 0.04 | — | 0.04 | PMID 24697546 | Open record: CsManD (D-mannonate dehydratase subgroup member), D-gluconate | |
| CsManD (D-mannonate dehydratase subgroup member) | Chromohalobacter salexigens | D-mannonateTable 1 | 0.02 | — | 0.005 | PMID 24697546 | Open record: CsManD (D-mannonate dehydratase subgroup member), D-mannonate | |
| CsManD (D-mannonate dehydratase subgroup member) | Chromohalobacter salexigens | D-mannonateTable 2 | — | — | 0.01 | PMID 24697546 | Open record: CsManD (D-mannonate dehydratase subgroup member), D-mannonate | |
| CsManD (D-mannonate dehydratase subgroup member)variant H315Q | Chromohalobacter salexigens | D-mannonate | — | — | 0.01 | PMID 24697546 | Open record: CsManD (D-mannonate dehydratase subgroup member) variant H315Q, D-mannonate | |
| CsManD (D-mannonate dehydratase subgroup member)variant P317A | Chromohalobacter salexigens | D-gluconate | — | — | 0.005 | PMID 24697546 | Open record: CsManD (D-mannonate dehydratase subgroup member) variant P317A, D-gluconate | |
| CsManD (D-mannonate dehydratase subgroup member)variant P317A | Chromohalobacter salexigens | D-mannonate | — | — | 0.1 | PMID 24697546 | Open record: CsManD (D-mannonate dehydratase subgroup member) variant P317A, D-mannonate | |
| mannonate dehydratase (EcManD) | Escherichia coli | D-mannonate | 0.81 | 4.79 | 0.17 calc. | pH 7.5, 37 °C | PMID 22796868 | Open record: mannonate dehydratase (EcManD), D-mannonate |
| mannonate dehydratase (EcManD)variant E185D | Escherichia coli | D-mannonate | 0.23 | 2.31 | 0.10 calc. | pH 7.5, 37 °C | PMID 22796868 | Open record: mannonate dehydratase (EcManD) variant E185D, D-mannonate |
| mannonate dehydratase (EcManD)variant E185G | Escherichia coli | D-mannonate | 0.94 | 4.55 | 0.21 calc. | pH 7.5, 37 °C | PMID 22796868 | Open record: mannonate dehydratase (EcManD) variant E185G, D-mannonate |
| mannonate dehydratase (EcManD)variant E186D | Escherichia coli | D-mannonate | 0.29 | 3.6 | 0.081 calc. | pH 7.5, 37 °C | PMID 22796868 | Open record: mannonate dehydratase (EcManD) variant E186D, D-mannonate |
| mannonate dehydratase (EcManD)variant E186G | Escherichia coli | D-mannonate | 1.1 | 5.3 | 0.21 calc. | pH 7.5, 37 °C | PMID 22796868 | Open record: mannonate dehydratase (EcManD) variant E186G, D-mannonate |
| mannonate dehydratase (EcManD)variant H32G | Escherichia coli | D-mannonate | 1.29 | 5.21 | 0.248 calc. | pH 7.5, 37 °C | PMID 22796868 | Open record: mannonate dehydratase (EcManD) variant H32G, D-mannonate |
| mannonate dehydratase (EcManD)variant N103A/D109A | Escherichia coli | D-mannonate | 0.1 | 4.08 | 0.025 calc. | pH 7.5, 37 °C | PMID 22796868 | Open record: mannonate dehydratase (EcManD) variant N103A/D109A, D-mannonate |
| mannonate dehydratase (EcManD)variant N36G | Escherichia coli | D-mannonate | 1.4 | 4.67 | 0.30 calc. | pH 7.5, 37 °C | PMID 22796868 | Open record: mannonate dehydratase (EcManD) variant N36G, D-mannonate |
| NaManD (D-mannonate dehydratase) | Novosphingobium aromaticivorans | D-mannonate | 1.3 | — | 3.2 | pH 7.5, 25 °C | PMID 24697546 | Open record: NaManD (D-mannonate dehydratase), D-mannonate |
| NaManD (D-mannonate dehydratase)variant A314P | Novosphingobium aromaticivorans | D-mannonate | — | — | 0.06 | PMID 24697546 | Open record: NaManD (D-mannonate dehydratase) variant A314P, D-mannonate |