EC 4.2.2.4: chondroitin ABC lyase
LyasesOpen in Browse
CatLog read 4 records for EC 4.2.2.4 from 1 paper, for 1 organism. Names in these papers: chondroitinase ABC I (cABC I).
EC 4.2.2.4 is no longer current; BRENDA: “deleted. Now classified as EC 4.2.2.20, chondroitin-sulfate-ABC endolyase and EC 4.2.2.21, chondroitin-sulfate-ABC exolyase”.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Enhancement of thermal stability of chondroitinase ABC I by site-directed mutagenesis: an insight from Ramachandran plot | Proteus vulgaris | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| chondroitinase ABC I (cABC I) | Proteus vulgaris | chondroitin 4-sulfate | 83 | 0.042 | 2 × 10³ | pH 6.8, 25 °C | PMID 23159774 | Open record: chondroitinase ABC I (cABC I), chondroitin 4-sulfate |
| chondroitinase ABC I (cABC I)variant Q140A | Proteus vulgaris | chondroitin 4-sulfate | 88 | 0.031 | 2.8 × 10³ | pH 6.8, 25 °C | PMID 23159774 | Open record: chondroitinase ABC I (cABC I) variant Q140A, chondroitin 4-sulfate |
| chondroitinase ABC I (cABC I)variant Q140G | Proteus vulgaris | chondroitin 4-sulfate | 89 | 0.034 | 2.6 × 10³ | pH 6.8, 25 °C | PMID 23159774 | Open record: chondroitinase ABC I (cABC I) variant Q140G, chondroitin 4-sulfate |
| chondroitinase ABC I (cABC I)variant Q140N | Proteus vulgaris | chondroitin 4-sulfate | 80 | 0.05 | 1.6 × 10³ | pH 6.8, 25 °C | PMID 23159774 | Open record: chondroitinase ABC I (cABC I) variant Q140N, chondroitin 4-sulfate |