EC 4.3.2.2: adenylosuccinate lyase

CatLog read 35 records for EC 4.3.2.2 from 3 papers, for 1 organism. Names in these papers: adenylosuccinate lyase.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 48 records for EC 4.3.2.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.3.2.2 in Browse.

Papers

Papers with records for EC 4.3.2.2
Paper	Organisms	Records
The characterization of mutant Bacillus subtilis adenylosuccinate lyases corresponding to severe human adenylosuccinate lyase deficiencies	Bacillus subtilis	12
Two novel mutant human adenylosuccinate lyases (ASLs) associated with autism and characterization of the equivalent mutant Bacillus subtilis ASL	Bacillus subtilis	12
His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis	Bacillus subtilis	11

Records

Records for EC 4.3.2.2 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
adenylosuccinate lyase	Bacillus subtilis	adenylosuccinate	1.7	0.0026	650	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase, adenylosuccinate
adenylosuccinate lyase	Bacillus subtilis	adenylosuccinate	1.3	0.00346	375	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase, adenylosuccinate
adenylosuccinate lyase	Bacillus subtilis	adenylosuccinate	1.57	0.004	390	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase, adenylosuccinate
adenylosuccinate lyase	Bacillus subtilis	succinylaminoimidazole carboxamide ribotide	—	0.0064	—	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase, succinylaminoimidazole carboxamide ribotide
adenylosuccinate lyasevariant D65R	Bacillus subtilis	adenylosuccinate	1.07	0.0046	231	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant D65R, adenylosuccinate
adenylosuccinate lyasevariant D65R/D69E	Bacillus subtilis	adenylosuccinate	0.2	0.002	100	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant D65R/D69E, adenylosuccinate
adenylosuccinate lyasevariant D69E	Bacillus subtilis	adenylosuccinate	0.34	0.0013	264	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant D69E, adenylosuccinate
adenylosuccinate lyasevariant H141A + H68Q (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0063	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141A + H68Q (hybrid), adenylosuccinate
adenylosuccinate lyasevariant H141E + H68Q (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0079	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141E + H68Q (hybrid), adenylosuccinate
adenylosuccinate lyasevariant H141L + H68Q (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0055	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141L + H68Q (hybrid), adenylosuccinate
adenylosuccinate lyasevariant H141Q + H68A (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0175	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141Q + H68A (hybrid), adenylosuccinate
adenylosuccinate lyasevariant H141Q + H68K (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0101	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141Q + H68K (hybrid), adenylosuccinate
adenylosuccinate lyasevariant H141Q + H68Q (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0084	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141Q + H68Q (hybrid), adenylosuccinate
adenylosuccinate lyasevariant H141Q + H68Q (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0092	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141Q + H68Q (hybrid), adenylosuccinate
adenylosuccinate lyasevariant H141Q + R67M:H68Q (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0123	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141Q + R67M:H68Q (hybrid), adenylosuccinate
adenylosuccinate lyasevariant H141R	Bacillus subtilis	adenylosuccinate	2.8 × 10⁻⁵	0.0067	0.0042	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141R, adenylosuccinate
adenylosuccinate lyasevariant H141R + H68Q (hybrid)	Bacillus subtilis	adenylosuccinate	—	0.0133	—	pH 7, 25 °C	PMID 9890879	Open record: adenylosuccinate lyase variant H141R + H68Q (hybrid), adenylosuccinate
adenylosuccinate lyasevariant I123R	Bacillus subtilis	adenylosuccinate	1.04	0.00218	476	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant I123R, adenylosuccinate
adenylosuccinate lyasevariant I123R	Bacillus subtilis	succinylaminoimidazole carboxamide ribotide	—	0.00837	—	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant I123R, succinylaminoimidazole carboxamide ribotide
adenylosuccinate lyasevariant I123W	Bacillus subtilis	adenylosuccinate	0.46	0.00334	138	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant I123W, adenylosuccinate
adenylosuccinate lyasevariant I123W	Bacillus subtilis	succinylaminoimidazole carboxamide ribotide	—	0.00537	—	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant I123W, succinylaminoimidazole carboxamide ribotide
adenylosuccinate lyasevariant I62D	Bacillus subtilis	adenylosuccinate	0.03	0.0551	0.5	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant I62D, adenylosuccinate
adenylosuccinate lyasevariant I62D/D65R	Bacillus subtilis	adenylosuccinate	0.05	0.0488	1	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant I62D/D65R, adenylosuccinate
adenylosuccinate lyasevariant I62D/D65R/D69E	Bacillus subtilis	adenylosuccinate	0.06	0.0107	5	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant I62D/D65R/D69E, adenylosuccinate
adenylosuccinate lyasevariant I62D/D69E	Bacillus subtilis	adenylosuccinate	0.03	0.0177	1	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant I62D/D69E, adenylosuccinate
adenylosuccinate lyasevariant I62E	Bacillus subtilis	adenylosuccinate	0.07	0.0175	3	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant I62E, adenylosuccinate
adenylosuccinate lyasevariant I62E/D65R	Bacillus subtilis	adenylosuccinate	0.48	0.0181	26	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant I62E/D65R, adenylosuccinate
adenylosuccinate lyasevariant I62E/D65R/D69E	Bacillus subtilis	adenylosuccinate	0.23	0.0061	37	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant I62E/D65R/D69E, adenylosuccinate
adenylosuccinate lyasevariant I62E/D69E	Bacillus subtilis	adenylosuccinate	0.08	0.0043	19	pH 7, 25 °C	PMID 15471876	Open record: adenylosuccinate lyase variant I62E/D69E, adenylosuccinate
adenylosuccinate lyasevariant M10L	Bacillus subtilis	adenylosuccinate	1.59	0.0038	418	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant M10L, adenylosuccinate
adenylosuccinate lyasevariant M10L	Bacillus subtilis	succinylaminoimidazole carboxamide ribotide	—	0.0107	—	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant M10L, succinylaminoimidazole carboxamide ribotide
adenylosuccinate lyasevariant T367R	Bacillus subtilis	adenylosuccinate	0.85	0.00163	519	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant T367R, adenylosuccinate
adenylosuccinate lyasevariant T367R	Bacillus subtilis	succinylaminoimidazole carboxamide ribotide	—	0.01326	—	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant T367R, succinylaminoimidazole carboxamide ribotide
adenylosuccinate lyasevariant T367S	Bacillus subtilis	adenylosuccinate	0.8	0.00156	514	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant T367S, adenylosuccinate
adenylosuccinate lyasevariant T367S	Bacillus subtilis	succinylaminoimidazole carboxamide ribotide	—	0.01437	—	pH 7, 25 °C	PMID 12876319	Open record: adenylosuccinate lyase variant T367S, succinylaminoimidazole carboxamide ribotide