EC 4.4.1.20: leukotriene-C4 synthase
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CatLog read 88 records for EC 4.4.1.20 from 3 papers, for 1 organism. Names in these papers: leukotriene C4 synthase (LTC4S), leukotriene C4 synthase (LTC_4S).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 51 records for EC 4.4.1.20 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.4.1.20 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The catalytic architecture of leukotriene C4 synthase with two arginine residues | Homo sapiens | 46 |
| Site-directed mutagenesis of human leukotriene C4 synthase | Homo sapiens | 36 |
| Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity | Homo sapiens | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| leukotriene C4 synthase (LTC4S) | Homo sapiens | 5(S)-trans-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid | 105 | 0.076 | 1.39 × 10³ | pH 7.8 | PMID 27365393 | Open record: leukotriene C4 synthase (LTC4S), 5(S)-trans-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathioneLTC4-Me quantified by RP-HPLC; cosubstrate LTA4-Me; Table 2 | — | 0.52 | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathioneTable 2 | — | 0.188 | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathioneTable 2 | — | 0.189 | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathioneLTC4-Me quantified by RP-HPLC; cosubstrate LTA4-Me | 2.11 | — | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathionein the text | 2.22 | — | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathionein the text | 1.72 | — | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathionein the text | — | — | 11.9 | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathioneGSH varied 2-10 mM with fixed 20 µM LTA4; 2 min reaction | — | — | 2.8 | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | glutathioneLTC4-Me quantified by RP-HPLC; cosubstrate LTA4-Me | — | — | 4.1 | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), glutathione |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 | — | — | 629 | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00408 | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00344 | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00445 | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 methyl esterin the text | 1.69 | — | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 methyl esterin the text | 1.97 | — | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 methyl esterin the text | 2.1 | — | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 methyl esterin the text | — | — | 577 | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | leukotriene A4 methyl esterin the text | — | — | 421 | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S) | Homo sapiens | reduced glutathione | 19 | 0.07 | 270 | pH 7.8 | PMID 27365393 | Open record: leukotriene C4 synthase (LTC4S), reduced glutathione |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | glutathioneTable 2 | — | 16.7 | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | glutathioneTable 2 | — | 12.8 | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | glutathioneTable 2 | — | 24.6 | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | glutathionein the text | 0.0692 | — | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | glutathionein the text | 0.2335 | — | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | glutathionein the text | 0.1965 | — | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | glutathionein the text | — | — | 0.0155 | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00385 | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00709 | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00569 | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | leukotriene A4 methyl esterin the text | 0.0197 | — | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | leukotriene A4 methyl esterin the text | 0.0682 | — | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | leukotriene A4 methyl esterin the text | 0.0532 | — | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R104A | Homo sapiens | leukotriene A4 methyl esterin the text | — | — | 9.7 | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R104A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | glutathioneTable 2 | — | 0.104 | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | glutathioneTable 2 | — | 0.0541 | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | glutathioneTable 2 | — | 0.0669 | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | glutathionein the text | 0.0243 | — | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | glutathionein the text | 0.0247 | — | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | glutathionein the text | 0.0222 | — | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | glutathionein the text | — | — | 0.46 | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, glutathione |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00609 | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00555 | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | leukotriene A4 methyl esterTable 2 | — | 0.00839 | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | leukotriene A4 methyl esterin the text | 0.0213 | — | — | pH 7 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | leukotriene A4 methyl esterin the text | 0.0202 | — | — | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | leukotriene A4 methyl esterin the text | 0.0277 | — | — | pH 9 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant R31A | Homo sapiens | leukotriene A4 methyl esterin the text | — | — | 3.63 | pH 8 | PMID 21454538 | Open record: leukotriene C4 synthase (LTC4S) variant R31A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC4S)variant S36E | Homo sapiens | 5(S)-trans-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid | — | — | 130 | pH 7.8 | PMID 27365393 | Open record: leukotriene C4 synthase (LTC4S) variant S36E, 5(S)-trans-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid |
| leukotriene C4 synthase (LTC4S)variant S36E | Homo sapiens | reduced glutathione | 3 | 0.12 | 26 | pH 7.8 | PMID 27365393 | Open record: leukotriene C4 synthase (LTC4S) variant S36E, reduced glutathione |
| leukotriene C4 synthase (LTC4S)variant T40E | Homo sapiens | 5(S)-trans-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid | 62 | 0.085 | 770 | pH 7.8 | PMID 27365393 | Open record: leukotriene C4 synthase (LTC4S) variant T40E, 5(S)-trans-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid |
| leukotriene C4 synthase (LTC4S)variant T40E | Homo sapiens | reduced glutathione | 12 | 0.22 | 50 | pH 7.8 | PMID 27365393 | Open record: leukotriene C4 synthase (LTC4S) variant T40E, reduced glutathione |
| leukotriene C4 synthase (LTC_4S) | Homo sapiens | glutathione (reduced) | — | 1.4 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S), glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S) | Homo sapiens | leukotriene A4 methyl ester | — | 0.0074 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)hybrid A (LTC4S/FLAP chimera: third hydrophobic domain and carboxyl terminus of FLAP) | Homo sapiens | leukotriene A4 methyl ester | — | 0.0056 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) hybrid A (LTC4S/FLAP chimera: third hydrophobic domain and carboxyl terminus of FLAP), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)hybrid C (LTC4S/FLAP chimera: residues 66-81 replaced by FLAP residues 70-85, plus P78L) | Homo sapiens | leukotriene A4 methyl ester | — | 0.0095 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) hybrid C (LTC4S/FLAP chimera: residues 66-81 replaced by FLAP residues 70-85, plus P78L), leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant A52S | Homo sapiens | glutathione (reduced) | — | 30 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant A52S, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant A52S | Homo sapiens | leukotriene A4 methyl ester | — | 0.0045 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant A52S, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant C82V | Homo sapiens | glutathione (reduced)assay on solubilized COS cell microsomes; 0.4% Triton X-102 | — | 2 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant C82V, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant C82V | Homo sapiens | glutathione (reduced)3-100 ng purified enzyme per assay | — | 0.9 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant C82V, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant C82V | Homo sapiens | leukotriene A4 methyl esterassay on solubilized COS cell microsomes; 0.4% Triton X-102 | — | 0.0109 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant C82V, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant C82V | Homo sapiens | leukotriene A4 methyl ester3-100 ng purified enzyme per assay | — | 0.0063 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant C82V, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant L62T | Homo sapiens | glutathione (reduced) | — | 2.5 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant L62T, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant L62T | Homo sapiens | leukotriene A4 methyl ester | — | 0.0067 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant L62T, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant N55A | Homo sapiens | glutathione (reduced) | — | 10.7 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant N55A, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant N55A | Homo sapiens | leukotriene A4 methyl ester | — | 0.0077 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant N55A, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant R51H | Homo sapiens | glutathione (reduced)assay on solubilized COS cell microsomes; 0.4% Triton X-102 | — | 3.8 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant R51H, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant R51H | Homo sapiens | glutathione (reduced)3-100 ng purified enzyme per assay | — | 1.5 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant R51H, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant R51H | Homo sapiens | leukotriene A4 methyl esterassay on solubilized COS cell microsomes; 0.4% Triton X-102 | — | 0.0064 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant R51H, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant R51H | Homo sapiens | leukotriene A4 methyl ester3-100 ng purified enzyme per assay | — | 0.0063 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant R51H, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant R51I/wild-type covalent pseudo-heterodimer | Homo sapiens | glutathione (reduced) | — | 3.2 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant R51I/wild-type covalent pseudo-heterodimer, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant R51I/wild-type covalent pseudo-heterodimer | Homo sapiens | leukotriene A4 methyl ester | — | 0.0065 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant R51I/wild-type covalent pseudo-heterodimer, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant R51K | Homo sapiens | glutathione (reduced) | — | 2.3 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant R51K, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant R51K | Homo sapiens | leukotriene A4 methyl ester | — | 0.0094 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant R51K, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant V49F | Homo sapiens | glutathione (reduced) | — | 9.2 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant V49F, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant V49F | Homo sapiens | leukotriene A4 methyl ester | — | 0.01 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant V49F, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant V69T | Homo sapiens | glutathione (reduced) | — | 2 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant V69T, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant V69T | Homo sapiens | leukotriene A4 methyl ester | — | 0.019 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant V69T, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant Y109I | Homo sapiens | glutathione (reduced) | — | 1.6 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y109I, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant Y109I | Homo sapiens | leukotriene A4 methyl ester | — | 0.02 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y109I, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant Y59F | Homo sapiens | glutathione (reduced) | — | 15.5 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y59F, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant Y59F | Homo sapiens | leukotriene A4 methyl ester | — | 0.019 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y59F, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant Y93F | Homo sapiens | glutathione (reduced)assay on solubilized COS cell microsomes; 0.4% Triton X-102 | — | 10 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y93F, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant Y93F | Homo sapiens | glutathione (reduced)3-100 ng purified enzyme per assay | — | 9.9 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y93F, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant Y93F | Homo sapiens | leukotriene A4 methyl esterassay on solubilized COS cell microsomes; 0.4% Triton X-102 | — | 0.02 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y93F, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant Y93F | Homo sapiens | leukotriene A4 methyl ester3-100 ng purified enzyme per assay | — | 0.0054 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y93F, leukotriene A4 methyl ester |
| leukotriene C4 synthase (LTC_4S)variant Y97F | Homo sapiens | glutathione (reduced) | — | 16.5 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y97F, glutathione (reduced) |
| leukotriene C4 synthase (LTC_4S)variant Y97F | Homo sapiens | leukotriene A4 methyl ester | — | 0.0165 | — | pH 7.6 | PMID 9153254 | Open record: leukotriene C4 synthase (LTC_4S) variant Y97F, leukotriene A4 methyl ester |