EC 4.99.1.9: coproporphyrin ferrochelatase
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CatLog read 14 records for EC 4.99.1.9 from 1 paper, for 1 organism. Names in these papers: ferrochelatase (HemH).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 14 records for EC 4.99.1.9 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.99.1.9 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| A high-throughput screen for porphyrin metal chelatases: application to the directed evolution of ferrochelatases for metalloporphyrin biosynthesis | Bacillus subtilis | 14 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| ferrochelatase (HemH) | Bacillus subtilis | ferrous iron (Fe(II)) | — | 0.013 | — | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH), ferrous iron (Fe(II)) |
| ferrochelatase (HemH) | Bacillus subtilis | protoporphyrin IX | 0.023 | 9.1 × 10⁻⁴ | 26 calc. | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH), protoporphyrin IX |
| ferrochelatase (HemH)variant D76G/K102T (M2) | Bacillus subtilis | ferrous iron (Fe(II)) | — | 0.021 | — | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant D76G/K102T (M2), ferrous iron (Fe(II)) |
| ferrochelatase (HemH)variant D76G/K102T (M2) | Bacillus subtilis | protoporphyrin IX | 0.033 | 4.4 × 10⁻⁴ | 76 calc. | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant D76G/K102T (M2), protoporphyrin IX |
| ferrochelatase (HemH)variant E61K (M3) | Bacillus subtilis | ferrous iron (Fe(II)) | — | 0.017 | — | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant E61K (M3), ferrous iron (Fe(II)) |
| ferrochelatase (HemH)variant E61K (M3) | Bacillus subtilis | protoporphyrin IX | 0.04 | 7.8 × 10⁻⁴ | 51 calc. | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant E61K (M3), protoporphyrin IX |
| ferrochelatase (HemH)variant E61K/L185Q/G212D (M6) | Bacillus subtilis | ferrous iron (Fe(II)) | — | 0.014 | — | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant E61K/L185Q/G212D (M6), ferrous iron (Fe(II)) |
| ferrochelatase (HemH)variant E61K/L185Q/G212D (M6) | Bacillus subtilis | protoporphyrin IX | 0.055 | 8.6 × 10⁻⁴ | 64 calc. | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant E61K/L185Q/G212D (M6), protoporphyrin IX |
| ferrochelatase (HemH)variant M11V/G104A (M4) | Bacillus subtilis | ferrous iron (Fe(II)) | — | 0.0094 | — | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant M11V/G104A (M4), ferrous iron (Fe(II)) |
| ferrochelatase (HemH)variant M11V/G104A (M4) | Bacillus subtilis | protoporphyrin IX | 0.038 | 0.0013 | 29 calc. | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant M11V/G104A (M4), protoporphyrin IX |
| ferrochelatase (HemH)variant R31G (M5) | Bacillus subtilis | ferrous iron (Fe(II)) | — | 0.01 | — | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant R31G (M5), ferrous iron (Fe(II)) |
| ferrochelatase (HemH)variant R31G (M5) | Bacillus subtilis | protoporphyrin IX | 0.02 | 8.3 × 10⁻⁴ | 24 calc. | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant R31G (M5), protoporphyrin IX |
| ferrochelatase (HemH)variant T302A (M1) | Bacillus subtilis | ferrous iron (Fe(II)) | — | 0.019 | — | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant T302A (M1), ferrous iron (Fe(II)) |
| ferrochelatase (HemH)variant T302A (M1) | Bacillus subtilis | protoporphyrin IX | 0.032 | 7.9 × 10⁻⁴ | 40 calc. | pH 7.6, 30 °C | PMID 15300829 | Open record: ferrochelatase (HemH) variant T302A (M1), protoporphyrin IX |