EC 5.3.1.12: glucuronate isomerase
IsomerasesOpen in Browse
CatLog read 22 records for EC 5.3.1.12 from 1 paper, for 1 organism. Names in these papers: uronate isomerase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 6 records for EC 5.3.1.12 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 5.3.1.12 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily | Escherichia coli | 22 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| uronate isomerase | Escherichia coli | D-glucuronate | 196 | 0.5 | 400 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase, D-glucuronate |
| uronate isomerasevariant D238N | Escherichia coli | D-glucuronate | 60 | 1.3 | 46 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant D238N, D-glucuronate |
| uronate isomerasevariant D412A | Escherichia coli | D-glucuronate | 0.009 | 0.4 | 0.021 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant D412A, D-glucuronate |
| uronate isomerasevariant D412N | Escherichia coli | D-glucuronate | 0.6 | 1 | 0.6 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant D412N, D-glucuronate |
| uronate isomerasevariant H297A | Escherichia coli | D-glucuronate | 10 | 220 | 0.043 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant H297A, D-glucuronate |
| uronate isomerasevariant H297N | Escherichia coli | D-glucuronate | 30 | 56 | 0.5 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant H297N, D-glucuronate |
| uronate isomerasevariant H33A | Escherichia coli | D-glucuronate | 0.6 | 0.2 | 3 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant H33A, D-glucuronate |
| uronate isomerasevariant H33N | Escherichia coli | D-glucuronate | 2.1 | 0.05 | 47 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant H33N, D-glucuronate |
| uronate isomerasevariant H35A | Escherichia coli | D-glucuronate | 0.7 | 39 | 0.018 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant H35A, D-glucuronate |
| uronate isomerasevariant H35N | Escherichia coli | D-glucuronate | 4 | 9.4 | 0.43 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant H35N, D-glucuronate |
| uronate isomerasevariant H59A | Escherichia coli | D-glucuronate | 0.6 | 0.7 | 0.83 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant H59A, D-glucuronate |
| uronate isomerasevariant H59N | Escherichia coli | D-glucuronate | 15 | 0.7 | 21 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant H59N, D-glucuronate |
| uronate isomerasevariant R186K | Escherichia coli | D-glucuronate | 54 | 2.6 | 21 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant R186K, D-glucuronate |
| uronate isomerasevariant R186M | Escherichia coli | D-glucuronate | 4.7 | 38 | 0.13 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant R186M, D-glucuronate |
| uronate isomerasevariant R302K | Escherichia coli | D-glucuronate | 160 | 2.5 | 63 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant R302K, D-glucuronate |
| uronate isomerasevariant R302M | Escherichia coli | D-glucuronate | 180 | 200 | 0.88 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant R302M, D-glucuronate |
| uronate isomerasevariant R414K | Escherichia coli | D-glucuronate | 5.8 | 0.82 | 7.1 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant R414K, D-glucuronate |
| uronate isomerasevariant R414M | Escherichia coli | D-glucuronate | 0.7 | 1.4 | 0.54 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant R414M, D-glucuronate |
| uronate isomerasevariant W381A | Escherichia coli | D-glucuronate | 250 | 21 | 12 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant W381A, D-glucuronate |
| uronate isomerasevariant W381F | Escherichia coli | D-glucuronate | 16 | 1.7 | 9.5 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant W381F, D-glucuronate |
| uronate isomerasevariant Y60A | Escherichia coli | D-glucuronate | 13.9 | 0.21 | 66 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant Y60A, D-glucuronate |
| uronate isomerasevariant Y60F | Escherichia coli | D-glucuronate | 21.7 | 0.16 | 140 | pH 8, 30 °C | PMID 19678710 | Open record: uronate isomerase variant Y60F, D-glucuronate |