CatLogenzyme kinetics catalog

EC 5.4.2.1: phosphoglycerate mutase

IsomerasesOpen in Browse

CatLog read 41 records for EC 5.4.2.1 from 6 papers, for 4 organisms. Names in these papers: phosphoglycerate mutase, BB isoenzyme (BB-PGAM), phosphoglycerate mutase, cofactor-dependent phosphoglycerate mutase (dPGM), cofactor-independent phosphoglycerate mutase (iPGM) and 2 more.

EC 5.4.2.1 is no longer current; BRENDA: “transferred to EC 5.4.2.11 and EC 5.4.2.12”.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

Papers

PaperOrganismsRecords
Characterization of the first described mutation of human red blood cell phosphoglycerate mutaseHomo sapiens25
Development of a mutagenesis, expression and purification system for yeast phosphoglycerate mutase. Investigation of the role of active-site His181Saccharomyces cerevisiae8
The two analogous phosphoglycerate mutases of Escherichia coliEscherichia coli4
Control of glucose utilization in working perfused rat heartRattus norvegicus2
Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistrySaccharomyces cerevisiae1
A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymesSaccharomyces cerevisiae1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
cofactor-dependent phosphoglycerate mutase (dPGM)Escherichia coli2-phosphoglycerate2200.191.1 × 10³pH 7, 30 °CPMID 10437801Open
cofactor-dependent phosphoglycerate mutase (dPGM)Escherichia coli3-phosphoglycerate3300.21.6 × 10³pH 7, 30 °CPMID 10437801Open
cofactor-independent phosphoglycerate mutase (iPGM)Escherichia coli2-phosphoglycerate100.097100pH 7, 30 °CPMID 10437801Open
cofactor-independent phosphoglycerate mutase (iPGM)Escherichia coli3-phosphoglycerate220.21100pH 7, 30 °CPMID 10437801Open
Gpm1p (GPM, phosphoglycerate mutase)Saccharomyces cerevisiae2-phosphoglycerate4001.41280 calc.30 °CPMID 23831062Open
phosphoglycerate mutaseSaccharomyces cerevisiae2,3-bisphosphoglycerateunstimulated (no 2-phosphoglycollate)0.0087——pH 8, 30 °CPMID 1386023Open
phosphoglycerate mutaseSaccharomyces cerevisiae2,3-bisphosphoglyceratestimulated by 1 mM 2-phosphoglycollate0.16——pH 8, 30 °CPMID 1386023Open
phosphoglycerate mutaseSaccharomyces cerevisiae2,3-bisphosphoglycerate—0.0024—pH 8, 30 °CPMID 1386023Open
phosphoglycerate mutaseSaccharomyces cerevisiae2,3-bisphosphoglycerate—0.0081—pH 7, 30 °CPMID 1386023Open
phosphoglycerate mutaseSaccharomyces cerevisiae3-phospho-D-glycerate—1.2—pH 7, 30 °CPMID 10951190Open
phosphoglycerate mutaseSaccharomyces cerevisiae3-phosphoglycerate4900.74660pH 7, 30 °CPMID 1386023Open
phosphoglycerate mutaseSaccharomyces cerevisiae3-phosphoglycerate0.0074——pH 8, 30 °CPMID 1386023Open
phosphoglycerate mutasevariant H181ASaccharomyces cerevisiae2,3-bisphosphoglycerate—0.087—pH 7, 30 °CPMID 1386023Open
phosphoglycerate mutasevariant H181ASaccharomyces cerevisiae3-phosphoglycerate0.0780.0263pH 7, 30 °CPMID 1386023Open
phosphoglycerate mutase (3-P-glycerate mutase)Rattus norvegicus2-phosphoglycerate—0.139—pH 7.2, 38 °CPMID 7929251Open
phosphoglycerate mutase (3-P-glycerate mutase)Rattus norvegicus3-phosphoglycerate—0.145—pH 7.2, 38 °CPMID 7929251Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglycerate—0.001—pH 7.4, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglyceratefixed 0.1 mM 3-PGA; cosubstrate 3-PGA (0.1 mM)—2 × 10⁻⁴—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglyceratefixed 1 mM 3-PGA; cosubstrate 3-PGA (1 mM)—0.0013—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglyceratefixed 0.1 mM 3-PGA; cosubstrate 3-PGA (0.1 mM)—5 × 10⁻⁵—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglyceratefixed 1 mM 3-PGA; cosubstrate 3-PGA (1 mM)—4 × 10⁻⁴—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglyceratefixed 0.1 mM 3-PGA; cosubstrate 3-PGA (0.1 mM)—2 × 10⁻⁴—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglyceratefixed 1 mM 3-PGA; cosubstrate 3-PGA (1 mM)—0.0012—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglyceratefixed 0.1 mM 3-PGA; cosubstrate 3-PGA (0.1 mM)—1 × 10⁻⁴—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens2,3-bisphosphoglyceratefixed 1 mM 3-PGA; cosubstrate 3-PGA (1 mM)—8 × 10⁻⁴—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglycerate—0.4—pH 7.4, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglyceratefixed 0.5 μM 2,3-BPGA; cosubstrate 2,3-BPGA (0.5 μM)—0.1—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglyceratefixed 10 μM 2,3-BPGA; cosubstrate 2,3-BPGA (10 μM)—0.3—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglyceratefixed 0.5 μM 2,3-BPGA; cosubstrate 2,3-BPGA (0.5 μM)—0.1—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglyceratefixed 10 μM 2,3-BPGA; cosubstrate 2,3-BPGA (10 μM)—0.1—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglyceratefixed 0.5 μM 2,3-BPGA; cosubstrate 2,3-BPGA (0.5 μM)—0.2—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglyceratefixed 10 μM 2,3-BPGA; cosubstrate 2,3-BPGA (10 μM)—0.5—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglyceratefixed 0.5 μM 2,3-BPGA; cosubstrate 2,3-BPGA (0.5 μM)—0.1—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)Homo sapiens3-phosphoglyceratefixed 10 μM 2,3-BPGA; cosubstrate 2,3-BPGA (10 μM)—0.5—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)variant M230IHomo sapiens2,3-bisphosphoglyceratefixed 1 mM 3-PGA; cosubstrate 3-PGA (1 mM)—1 × 10⁻⁴—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)variant M230IHomo sapiens2,3-bisphosphoglyceratefixed 0.1 mM 3-PGA; cosubstrate 3-PGA (0.1 mM)—3 × 10⁻⁵—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)variant M230IHomo sapiens2,3-bisphosphoglyceratefixed 1 mM 3-PGA; cosubstrate 3-PGA (1 mM)—2 × 10⁻⁴—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)variant M230IHomo sapiens3-phosphoglyceratefixed 0.5 μM 2,3-BPGA; cosubstrate 2,3-BPGA (0.5 μM)—0.3—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)variant M230IHomo sapiens3-phosphoglyceratefixed 10 μM 2,3-BPGA; cosubstrate 2,3-BPGA (10 μM)—0.5—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)variant M230IHomo sapiens3-phosphoglyceratefixed 0.5 μM 2,3-BPGA; cosubstrate 2,3-BPGA (0.5 μM)—0.2—pH 7.1, 30 °CPMID 15949708Open
phosphoglycerate mutase, BB isoenzyme (BB-PGAM)variant M230IHomo sapiens3-phosphoglyceratefixed 10 μM 2,3-BPGA; cosubstrate 2,3-BPGA (10 μM)—0.3—pH 7.1, 30 °CPMID 15949708Open