EC 6.1.1.26: pyrrolysine-tRNAPyl ligase
LigasesOpen in Browse
CatLog read 2 records for EC 6.1.1.26 from 1 paper, for 1 organism. Names in these papers: N-acetyl lysyl-tRNA synthetase MmAcKRS1 (pyrrolysyl-tRNA synthetase, PylRS, variant), N-acetyl lysyl-tRNA synthetase MmAcKRS2 (pyrrolysyl-tRNA synthetase, PylRS, variant).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 15 records for EC 6.1.1.26 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.1.1.26 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| N-acetyl lysyl-tRNA synthetases evolved by a CcdB-based selection possess N-acetyl lysine specificity in vitro and in vivo | Methanosarcina mazei | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| N-acetyl lysyl-tRNA synthetase MmAcKRS1 (pyrrolysyl-tRNA synthetase, PylRS, variant)variant L301M/Y306L/L309A/C348F | Methanosarcina mazei | N-Acetyl lysine | 0.0323 | 35.3 | 9.15 × 10⁻⁴ calc. | PMID 22289181 | Open record: N-acetyl lysyl-tRNA synthetase MmAcKRS1 (pyrrolysyl-tRNA synthetase, PylRS, variant) variant L301M/Y306L/L309A/C348F, N-Acetyl lysine | |
| N-acetyl lysyl-tRNA synthetase MmAcKRS2 (pyrrolysyl-tRNA synthetase, PylRS, variant)variant L301M/Y306L/C348S/A315V | Methanosarcina mazei | N-Acetyl lysine | 0.00731 | 7.8 | 9.4 × 10⁻⁴ calc. | PMID 22289181 | Open record: N-acetyl lysyl-tRNA synthetase MmAcKRS2 (pyrrolysyl-tRNA synthetase, PylRS, variant) variant L301M/Y306L/C348S/A315V, N-Acetyl lysine |