CatLogenzyme kinetics catalog

EC 6.3.2.13: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase

LigasesOpen in Browse

CatLog read 20 records for EC 6.3.2.13 from 1 paper, for 1 organism. Names in these papers: MurE ligase (UDP-MurNAc-tripeptide ligase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 30 records for EC 6.3.2.13 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.3.2.13 in Browse.

Papers

PaperOrganismsRecords
Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosisMycobacterium tuberculosis20

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
MurE ligase (UDP-MurNAc-tripeptide ligase)Mycobacterium tuberculosisATP1.30.01776 calc.pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)Mycobacterium tuberculosismeso-2,6-diaminopimelic acid—0.078—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)Mycobacterium tuberculosisUDP-N-acetylmuramoyl-L-alanyl-D-glutamate—0.024—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant D392AMycobacterium tuberculosisATP0.10.11.0 calc.pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant D392AMycobacterium tuberculosismeso-2,6-diaminopimelic acid—0.113—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant D392AMycobacterium tuberculosisUDP-N-acetylmuramoyl-L-alanyl-D-glutamate—0.016—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant E220AMycobacterium tuberculosisATP0.570.1234.6 calc.pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant E220AMycobacterium tuberculosismeso-2,6-diaminopimelic acid—0.052—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant E220AMycobacterium tuberculosisUDP-N-acetylmuramoyl-L-alanyl-D-glutamate—0.148—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant K157AMycobacterium tuberculosisATP0.0830.00810 calc.pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant K157AMycobacterium tuberculosismeso-2,6-diaminopimelic acid—0.012—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant N449DMycobacterium tuberculosisATP0.050.060.83 calc.pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant N449DMycobacterium tuberculosismeso-2,6-diaminopimelic acid—0.324—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant N449DMycobacterium tuberculosisUDP-N-acetylmuramoyl-L-alanyl-D-glutamate—0.007—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant R451AMycobacterium tuberculosisATP0.0670.0154.4 calc.pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant R451AMycobacterium tuberculosismeso-2,6-diaminopimelic acid—0.473—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant R451AMycobacterium tuberculosisUDP-N-acetylmuramoyl-L-alanyl-D-glutamate—0.005—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant ΔN24 (MurEtr)Mycobacterium tuberculosisATP1.120.02153 calc.pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant ΔN24 (MurEtr)Mycobacterium tuberculosismeso-2,6-diaminopimelic acid—0.065—pH 8.5, 37 °CPMID 21153518Open
MurE ligase (UDP-MurNAc-tripeptide ligase)variant ΔN24 (MurEtr)Mycobacterium tuberculosisUDP-N-acetylmuramoyl-L-alanyl-D-glutamate—0.019—pH 8.5, 37 °CPMID 21153518Open