EC 6.3.2.7: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase
LigasesOpen in Browse
CatLog read 6 records for EC 6.3.2.7 from 2 papers, for 1 organism. Names in these papers: MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase), MurE (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase; L-lysine-adding).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 20 records for EC 6.3.2.7 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.3.2.7 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Purification and biochemical characterization of Mur ligases from Staphylococcus aureus | Staphylococcus aureus | 4 |
| Specificity determinants for lysine incorporation in Staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex | Staphylococcus aureus | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| MurE (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase; L-lysine-adding)variant D406A | Staphylococcus aureus | L-lysine | 0.001 | 2.8 | 0.001 | pH 8.6, 37 °C | PMID 24064214 | Open record: MurE (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase; L-lysine-adding) variant D406A, L-lysine |
| MurE (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase; L-lysine-adding)variant P408A | Staphylococcus aureus | L-lysine | 0.283 | 3.1 | 0.091 | pH 8.6, 37 °C | PMID 24064214 | Open record: MurE (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase; L-lysine-adding) variant P408A, L-lysine |
| MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase) | Staphylococcus aureus | adenosine 5'-triphosphate | — | 0.53 | — | pH 8.6, 37 °C | PMID 20659527 | Open record: MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase), adenosine 5'-triphosphate |
| MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase) | Staphylococcus aureus | L-lysine | — | 0.55 | — | pH 8.6, 37 °C | PMID 20659527 | Open record: MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase), L-lysine |
| MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase) | Staphylococcus aureus | L-ornithine | — | 37 | — | pH 8.6, 37 °C | PMID 20659527 | Open record: MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase), L-ornithine |
| MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase) | Staphylococcus aureus | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate | — | 0.087 | — | pH 8.6, 37 °C | PMID 20659527 | Open record: MurE ligase (UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase), UDP-N-acetylmuramoyl-L-alanyl-D-glutamate |