EC 1.14.17.3: peptidylglycine monooxygenase
OxidoreductasesOpen in Browse
CatLog read 76 records for EC 1.14.17.3 from 3 papers, for 1 organism. Names in these papers: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 57 records for EC 1.14.17.3 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.14.17.3 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM) | Rattus norvegicus | 57 |
| Glutathione, S-substituted glutathiones, and leukotriene C4 as substrates for peptidylglycine alpha-amidating monooxygenase | Rattus norvegicus | 12 |
| Use of endoproteases to identify catalytic domains, linker regions, and functional interactions in soluble peptidylglycine alpha-amidating monooxygenase | Rattus norvegicus | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | glutathione | — | 0.13 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, glutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | leukotriene C4 | — | 0.035 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, leukotriene C4 |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-(1,2-dicarboxyethyl)glutathione | — | 1.1 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-(1,2-dicarboxyethyl)glutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-(p-nitrobenzyl)glutathione | — | 0.027 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-(p-nitrobenzyl)glutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-butylglutathione | — | 0.067 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-butylglutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-decylglutathioneapparent Km | — | 0.016 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-decylglutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-decylglutathioneapparent kcat/Km | — | — | 260 | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-decylglutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-ethylglutathione | — | 0.23 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-ethylglutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-hexylglutathione | — | 0.035 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-hexylglutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-methylglutathione | — | 0.27 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-methylglutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-octylglutathione | — | 0.032 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-octylglutathione |
| bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A | Rattus norvegicus | S-propylglutathione | — | 0.11 | — | pH 6, 37 °C | PMID 12646261 | Open record: bifunctional peptidylglycine α-amidating monooxygenase (PAM), type A, S-propylglutathione |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | L-pyroglutamylglycine | 9.3 | 0.31 | 30 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), L-pyroglutamylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(1H-indol-3-ylacetyl)glycine | 7.3 | 0.3 | 25 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(1H-indol-3-ylacetyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(2,6-difluorobenzoyl)glycine | 4.3 | 19 | 0.23 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(2,6-difluorobenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(2-aminobenzoyl)glycine | 4.2 | 1.4 | 2.9 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(2-aminobenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(2-furoyl)glycine | 7.5 | 2.7 | 2.8 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(2-furoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(2-hydroxybenzoyl)glycine | 4.9 | 0.86 | 7.1 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(2-hydroxybenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(2-iodobenzoyl)glycine | 3.1 | 3.4 | 0.91 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(2-iodobenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(2-methyl-3-phenylpropanoyl)glycine | 18 | 4.1 | 4.3 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(2-methyl-3-phenylpropanoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(2-methylbenzoyl)glycine | 7.9 | 4.3 | 1.8 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(2-methylbenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(2-phenylethanethioyl)glycine | 2.4 | 0.024 | 100 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(2-phenylethanethioyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(3-chlorobenzoyl)glycine | 7.8 | 2.2 | 3.6 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(3-chlorobenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(3-methylbenzoyl)glycine | 6.4 | 1.4 | 4.7 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(3-methylbenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(3-phenylpropanethioyl)glycine | 1.6 | 0.038 | 42 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(3-phenylpropanethioyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(3-phenylpropanoyl)glycine | 9.9 | 0.94 | 11 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(3-phenylpropanoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-aminobenzoyl)glycine | 5.6 | 2.6 | 2.2 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-aminobenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-bromobenzoyl)glycine | 2.5 | 0.52 | 4.9 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-bromobenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-chlorobenzoyl)glycine | 4.1 | 0.62 | 6.6 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-chlorobenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-ethylbenzoyl)glycine | 3.6 | 1.2 | 3.1 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-ethylbenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-hydroxybenzoyl)glycine | 5.8 | 1.7 | 3.5 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-hydroxybenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-methoxybenzoyl)glycine | 5.3 | 0.82 | 6.4 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-methoxybenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-methylbenzoyl)glycine | 5.7 | 1.8 | 3.2 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-methylbenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-methylpentanoyl)glycine | 6.6 | 0.28 | 23 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-methylpentanoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-nitrobenzoyl)glycine | 4.2 | 0.47 | 8.9 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-nitrobenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-nitrobenzoyl)glycylglycine | 8.7 | 0.11 | 76 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-nitrobenzoyl)glycylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-phenylbutanoyl)glycine | 11 | 0.16 | 70 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-phenylbutanoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(4-propylbenzoyl)glycine | 5.1 | 1.2 | 4.2 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(4-propylbenzoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(5-phenylpentanoyl)glycine | 12 | 0.15 | 76 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(5-phenylpentanoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(6-phenylhexanoyl)glycine | 11 | 0.051 | 200 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(6-phenylhexanoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(8-phenyloctanoyl)glycine | 8 | 0.1 | 76 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(8-phenyloctanoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(benzyloxycarbonyl)-D-alanine | 1.4 | 35 | 0.041 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(benzyloxycarbonyl)-D-alanine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(benzyloxycarbonyl)glycine | 8.6 | 0.59 | 15 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(benzyloxycarbonyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(chloroacetyl)glycylglycine | 8.9 | 0.42 | 21 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(chloroacetyl)glycylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(phenylacetyl)glycine | 7.4 | 0.16 | 46 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(phenylacetyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(phenylcarbamoyl)glycine | 9.7 | 0.36 | 27 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(phenylcarbamoyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(pyridine-3-carbonyl)glycine | 8 | 1.9 | 4.2 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(pyridine-3-carbonyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(tert-butoxycarbonyl)glycine | 6.3 | 3.7 | 1.7 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(tert-butoxycarbonyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(tert-butoxycarbonyl)glycylglycine | 7.5 | 0.3 | 25 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(tert-butoxycarbonyl)glycylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-(thiophene-2-carbonyl)glycine | 9.3 | 1.6 | 6 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-(thiophene-2-carbonyl)glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-[(2-Phenylcyclopropyl)carbonyl] glycine | 10 | 0.9 | 11 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-[(2-Phenylcyclopropyl)carbonyl] glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-[(benzylsulfanyl)carbonyl]glycine | 0.69 | 0.059 | 12 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-[(benzylsulfanyl)carbonyl]glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-[(phenylsulfanyl)acetyl]glycine | 4.6 | 0.19 | 25 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-[(phenylsulfanyl)acetyl]glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-[(propan-2-ylsulfanyl)acetyl]glycine | 1.8 | 0.22 | 8.2 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-[(propan-2-ylsulfanyl)acetyl]glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-[(pyridin-2-ylsulfanyl)acetyl]glycine | 3 | 0.036 | 83 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-[(pyridin-2-ylsulfanyl)acetyl]glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-[3-(furan-2-yl)acryloyl]glycine | 3.4 | 1.2 | 2.8 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-[3-(furan-2-yl)acryloyl]glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-[4-(trifluoromethyl)benzoyl]glycine | 2.8 | 0.77 | 3.6 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-[4-(trifluoromethyl)benzoyl]glycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-acetyl-D-alanine | 1.3 | 1.4 × 10³ | 9.5 × 10⁻⁴ | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-acetyl-D-alanine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-acetylglycine | 8 | 9.3 | 0.86 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-acetylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-acetylglycine2.5% (v/v) DMSO | — | 15 | — | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-acetylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-acetylglycylglycine | 8.9 | 1.5 | 5.9 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-acetylglycylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-benzoyl-D-alanine | 0.27 | 84 | 0.0032 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-benzoyl-D-alanine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-benzoylglycine | 8.2 | 1.3 | 6.2 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-benzoylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-benzoylglycylglycine | 12 | 0.078 | 160 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-benzoylglycylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-benzoylglycylglycylglycine | 8.8 | 0.31 | 29 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-benzoylglycylglycylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-cinnamoylglycine | 8.4 | 0.23 | 36 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-cinnamoylglycine |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-dansyl-Tyr-Val-D-Ala | 0.91 | 0.031 | 30 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-dansyl-Tyr-Val-D-Ala |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-dansyl-Tyr-Val-Gly1% (v/v) ethanol; (5.0 mM) and O2 (200 uM), fixed | 1.4 | 0.0027 | 500 | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-dansyl-Tyr-Val-Gly |
| peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity) | Rattus norvegicus | N-dansyl-Tyr-Val-Gly1.0% (v/v) ethanol; 6.0 mM sodium ascorbate; 2.5% (v/v) DMSO | — | 0.0149 | — | pH 6, 37 °C | PMID 18952446 | Open record: peptidylglycine alpha-amidating monooxygenase (bifunctional PAM; PHM activity), N-dansyl-Tyr-Val-Gly |
| peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM | Rattus norvegicus | N-acetyl-L-tyrosyl-L-valyl-glycinesecreted by stably transfected hEK-293 cells; purified | 7 | 0.014 | 500 calc. | pH 5.5, 37 °C | PMID 8486658 | Open record: peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM, N-acetyl-L-tyrosyl-L-valyl-glycine |
| peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM | Rattus norvegicus | N-acetyl-L-tyrosyl-L-valyl-glycineTable II | 16 | 0.008 | 2.0 × 10³ calc. | pH 5.5, 37 °C | PMID 8486658 | Open record: peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM, N-acetyl-L-tyrosyl-L-valyl-glycine |
| peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM | Rattus norvegicus | N-acetyl-L-tyrosyl-L-valyl-glycineTable II | 14 | 0.009 | 1.6 × 10³ calc. | pH 5.5, 37 °C | PMID 8486658 | Open record: peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM, N-acetyl-L-tyrosyl-L-valyl-glycine |
| peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM | Rattus norvegicus | N-acetyl-L-tyrosyl-L-valyl-glycinerPAM-3 digested with endoprotease Lys-C (36-kDa PHM protein) | 17 | 0.011 | 1.5 × 10³ calc. | pH 5.5, 37 °C | PMID 8486658 | Open record: peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM, N-acetyl-L-tyrosyl-L-valyl-glycine |
| peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM | Rattus norvegicus | N-acetyl-L-tyrosyl-L-valyl-glycinerPHM-s pool C; secreted by hEK-293 cells; Table II | 4 | 0.018 | 220 calc. | pH 5.5, 37 °C | PMID 8486658 | Open record: peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM, N-acetyl-L-tyrosyl-L-valyl-glycine |
| peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM | Rattus norvegicus | N-acetyl-L-tyrosyl-L-valyl-glycinesecreted by stably transfected hEK-293 cells; purified | — | 0.018 | — | pH 5.5, 37 °C | PMID 8486658 | Open record: peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM, N-acetyl-L-tyrosyl-L-valyl-glycine |
| peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM | Rattus norvegicus | N-acetyl-L-tyrosyl-L-valyl-glycinerPAM-3 digested with trypsin (0.1 µg trypsin/ug PAM-3) | — | 0.008 | — | pH 5.5, 37 °C | PMID 8486658 | Open record: peptidylglycine alpha-hydroxylating monooxygenase (PHM) activity of PAM, N-acetyl-L-tyrosyl-L-valyl-glycine |