CatLogenzyme kinetics catalog

EC 1.8.1.14: CoA-disulfide reductase

OxidoreductasesOpen in Browse

CatLog read 38 records for EC 1.8.1.14 from 5 papers, for 3 organisms. Names in these papers: coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADR, coenzyme A-disulfide reductase (CoADR, BACoADR), coenzyme A-disulfide reductase (phCoADR), coenzyme A disulfide reductase (phCoADR; previously NOX2) and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 13 records for EC 1.8.1.14 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.8.1.14 in Browse.

Papers

PaperOrganismsRecords
Structure and substrate specificity of the pyrococcal coenzyme A disulfide reductases/polysulfide reductases (CoADR/Psr): implications for S(0)-based respiration and a sulfur-dependent antioxidant…Pyrococcus horikoshii11
Pyridine nucleotide complexes with Bacillus anthracis coenzyme A-disulfide reductase: a structural analysis of dual NAD(P)H specificityBacillus anthracis8
A broader active site in Pyrococcus horikoshii CoA disulfide reductase accommodates larger substrates and reveals evidence of subunit asymmetryPyrococcus horikoshii8
Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii. Implications for this disulfide metabolism of anaerobic hyperthermophilesPyrococcus horikoshii6
Coenzyme A disulfide reductase, the primary low molecular weight disulfide reductase from Staphylococcus aureus. Purification and characterization of the native enzymeStaphylococcus aureus5

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
coenzyme A disulfide reductase (CoADR)Staphylococcus aureus3′-dephospho-coenzyme A disulfide1.4 × 10³0.141 × 10⁴pH 7.8, 37 °CPMID 9488707Open
coenzyme A disulfide reductase (CoADR)Staphylococcus aureus4,4′-diphosphopantethine5400.083.3 × 10³pH 7.8, 37 °CPMID 9488707Open
coenzyme A disulfide reductase (CoADR)Staphylococcus aureuscoenzyme A disulfide1 × 10³0.0118 × 10⁴pH 7.8, 37 °CPMID 9488707Open
coenzyme A disulfide reductase (CoADR)Staphylococcus aureuscoenzyme A-glutathione mixed disulfide8001.1720pH 7.8, 37 °CPMID 9488707Open
coenzyme A disulfide reductase (CoADR)Staphylococcus aureusNADPH1.02 × 10³0.00166 × 10⁵pH 7.8, 37 °CPMID 9488707Open
coenzyme A disulfide reductase (phCoADR; previously NOX2)Pyrococcus horikoshiicoenzyme A disulfide7.10.03240 calc.pH 7.5, 75 °CPMID 15720393Open
coenzyme A disulfide reductase (phCoADR; previously NOX2)Pyrococcus horikoshiiFAD5.90.022270 calc.pH 7.5, 75 °CPMID 15720393Open
coenzyme A disulfide reductase (phCoADR; previously NOX2)Pyrococcus horikoshiiNADHCoA disulfide reductase activity; cosubstrate CoA disulfide8.10.073110 calc.pH 7.5, 75 °CPMID 15720393Open
coenzyme A disulfide reductase (phCoADR; previously NOX2)Pyrococcus horikoshiiNADH100 µM FAD (footnote c); 115 µM O2 (Results text)8.20.073110 calc.pH 7.5, 75 °CPMID 15720393Open
coenzyme A disulfide reductase (phCoADR; previously NOX2)Pyrococcus horikoshiiNADPHCoA disulfide reductase activity; cosubstrate CoA disulfide7.2——pH 7.5, 75 °CPMID 15720393Open
coenzyme A disulfide reductase (phCoADR; previously NOX2)Pyrococcus horikoshiiNADPH100 µM FAD (footnote c); cosubstrate FAD20.013150 calc.pH 7.5, 75 °CPMID 15720393Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshii5,5'-dithiobis-2-nitrobenzoic acid0.690.1295.35pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiiCoA polysulfide6.560.094969pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiicoenzyme A persulfide100 µM NADH fixed (Table 2 footnote a); cosubstrate NADH1.110.020554pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiicoenzyme A persulfide100 µM NADPH fixed (Table 2 footnote a); cosubstrate NADPH1.50.056227pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiiglutathione persulfide0.35——pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiiNADHpersulfide; cosubstrate CoA persulfide1.070.013977pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiiNADHpolysulfide; cosubstrate CoA polysulfide8.860.12579pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiiNADPHpersulfide; cosubstrate CoA persulfide2.080.0127160pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiiNADPHpolysulfide; cosubstrate CoA polysulfide16.10.01411.2 × 10³pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiipolysulfide1.040.012385pH 8.1, 50 °CPMID 23530771Open
coenzyme A disulfide reductase/polysulfide reductase (CoADR/Psr), phCoADRPyrococcus horikoshiiTNB persulfide3.370.0251135pH 8.1, 50 °CPMID 23530771Open
coenzyme A-disulfide reductase (CoADR, BACoADR)Bacillus anthraciscoenzyme A-disulfidecosubstrate NADH—0.002—PMID 18399646Open
coenzyme A-disulfide reductase (CoADR, BACoADR)Bacillus anthraciscoenzyme A-disulfidecosubstrate NADPH—0.006—PMID 18399646Open
coenzyme A-disulfide reductase (CoADR, BACoADR)Bacillus anthracisNADH270.0012.7 × 10⁴PMID 18399646Open
coenzyme A-disulfide reductase (CoADR, BACoADR)Bacillus anthracisNADPH280.0039.3 × 10³PMID 18399646Open
coenzyme A-disulfide reductase (CoADR, BACoADR)variant Y367FBacillus anthracisNADH7——25 °CPMID 18399646Open
coenzyme A-disulfide reductase (CoADR, BACoADR)variant Y367FBacillus anthracisNADPH5——25 °CPMID 18399646Open
coenzyme A-disulfide reductase (CoADR, BACoADR)variant Y425FBacillus anthracisNADH0.9——25 °CPMID 18399646Open
coenzyme A-disulfide reductase (CoADR, BACoADR)variant Y425FBacillus anthracisNADPH0.3——25 °CPMID 18399646Open
coenzyme A-disulfide reductase (phCoADR)Pyrococcus horikoshiicoenzyme A disulfidecosubstrate NADPH4.40.05285 calc.pH 7.5, 75 °CPMID 29988575Open
coenzyme A-disulfide reductase (phCoADR)Pyrococcus horikoshiicoenzyme A disulfidecosubstrate NADH5.430.0286190 calc.pH 7.5, 75 °CPMID 29988575Open
coenzyme A-disulfide reductase (phCoADR)Pyrococcus horikoshiiNADH2.30.07332 calc.pH 7.5, 75 °CPMID 29988575Open
coenzyme A-disulfide reductase (phCoADR)Pyrococcus horikoshiiNADPH5.8——pH 7.5, 75 °CPMID 29988575Open
coenzyme A-disulfide reductase (phCoADR)variant Y65A/Y66A/P67G/H367GPyrococcus horikoshiicoenzyme A disulfidecosubstrate NADPH18.80.057330 calc.pH 7.5, 75 °CPMID 29988575Open
coenzyme A-disulfide reductase (phCoADR)variant Y65A/Y66A/P67G/H367GPyrococcus horikoshiicoenzyme A disulfidecosubstrate NADH1.80.08621 calc.pH 7.5, 75 °CPMID 29988575Open
coenzyme A-disulfide reductase (phCoADR)variant Y65A/Y66A/P67G/H367GPyrococcus horikoshiiNADH8.10.075110 calc.pH 7.5, 75 °CPMID 29988575Open
coenzyme A-disulfide reductase (phCoADR)variant Y65A/Y66A/P67G/H367GPyrococcus horikoshiiNADPH21.60.01641.32 × 10³ calc.pH 7.5, 75 °CPMID 29988575Open