EC 2.3.1.5: arylamine N-acetyltransferase

TransferasesOpen in Browse

CatLog read 173 records for EC 2.3.1.5 from 9 papers, for 19 organisms. Names in these papers: arylamine N-acetyltransferase (NAT), arylamine N-acetyltransferase 2 (NAT2), arylamine N-acetyltransferase (TBNAT), human NAT2 and 7 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 78 records for EC 2.3.1.5 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.5 in Browse.

Papers

Papers with records for EC 2.3.1.5
Paper	Organisms	Records
Identification and functional characterization of arylamine N-acetyltransferases in eubacteria: evidence for highly selective acetylation of 5-aminosalicylic acid	Bacteroides sp., Citrobacter amalonaticus and 12 more	42
Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190	hamster	33
Arylamine N-acetyltransferases: characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2	Homo sapiens	30
Kinetic and chemical mechanism of arylamine N-acetyltransferase from Mycobacterium tuberculosis	Mycobacterium tuberculosis	19
Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis	Mycobacterium marinum, Mycobacterium tuberculosis	15
Purification and biochemical properties of an N-hydroxyarylamine O-acetyltransferase from Escherichia coli	Escherichia coli	11
Arylamine N-acetyltransferase responsible for acetylation of 2-aminophenols in Streptomyces griseus	Streptomyces griseus	9
An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases	Mycobacterium smegmatis	8
NMR-based model reveals the structural determinants of mammalian arylamine N-acetyltransferase substrate specificity	Homo sapiens, hamster	6

Records

Records for EC 2.3.1.5 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
arylamine N-acetyltransferase (MMNAT)	Mycobacterium marinum	4-anisidine	5.2	3.7	1.405	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (MMNAT), 4-anisidine
arylamine N-acetyltransferase (MMNAT)	Mycobacterium marinum	5-aminosalicylic acid	5.2	1.7	3.058	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (MMNAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (MMNAT)	Mycobacterium marinum	acetyl coenzyme A	—	0.158	—	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (MMNAT), acetyl coenzyme A
arylamine N-acetyltransferase (MMNAT)	Mycobacterium marinum	isoniazid	1.7	6.2	0.274	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (MMNAT), isoniazid
arylamine N-acetyltransferase (MMNAT)chimera MM12TB3	Mycobacterium marinum	4-anisidine	0.3	1.8	0.166	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (MMNAT) chimera MM12TB3, 4-anisidine
arylamine N-acetyltransferase (MMNAT)chimera MM12TB3	Mycobacterium marinum	5-aminosalicylic acid	1.8	1.2	1.5	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (MMNAT) chimera MM12TB3, 5-aminosalicylic acid
arylamine N-acetyltransferase (MMNAT)chimera MM12TB3	Mycobacterium marinum	acetyl coenzyme A	—	0.181	—	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (MMNAT) chimera MM12TB3, acetyl coenzyme A
arylamine N-acetyltransferase (MMNAT)chimera MM12TB3	Mycobacterium marinum	isoniazid	0.3	6.1	0.0091	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (MMNAT) chimera MM12TB3, isoniazid
arylamine N-acetyltransferase (MSNAT)	Mycobacterium smegmatis	4-Anisidine	0.03	1.8	0.017	pH 8, 37 °C	PMID 12628650	Open record: arylamine N-acetyltransferase (MSNAT), 4-Anisidine
arylamine N-acetyltransferase (MSNAT)	Mycobacterium smegmatis	4-Bromoaniline	0.0086	1.8	0.0048	pH 8, 37 °C	PMID 12628650	Open record: arylamine N-acetyltransferase (MSNAT), 4-Bromoaniline
arylamine N-acetyltransferase (MSNAT)	Mycobacterium smegmatis	4-Butoxyaniline	0.039	0.33	0.12	pH 8, 37 °C	PMID 12628650	Open record: arylamine N-acetyltransferase (MSNAT), 4-Butoxyaniline
arylamine N-acetyltransferase (MSNAT)	Mycobacterium smegmatis	4-Chloroaniline	0.0069	2	0.0035	pH 8, 37 °C	PMID 12628650	Open record: arylamine N-acetyltransferase (MSNAT), 4-Chloroaniline
arylamine N-acetyltransferase (MSNAT)	Mycobacterium smegmatis	4-Ethoxyaniline	0.036	1.01	0.036	pH 8, 37 °C	PMID 12628650	Open record: arylamine N-acetyltransferase (MSNAT), 4-Ethoxyaniline
arylamine N-acetyltransferase (MSNAT)	Mycobacterium smegmatis	4-Iodoaniline	0.0098	1	0.0097	pH 8, 37 °C	PMID 12628650	Open record: arylamine N-acetyltransferase (MSNAT), 4-Iodoaniline
arylamine N-acetyltransferase (MSNAT)	Mycobacterium smegmatis	5-Aminosalicylate	0.044	0.25	0.18	pH 8, 37 °C	PMID 12628650	Open record: arylamine N-acetyltransferase (MSNAT), 5-Aminosalicylate
arylamine N-acetyltransferase (MSNAT)	Mycobacterium smegmatis	Hydralazine	0.063	0.08	0.79	pH 8, 37 °C	PMID 12628650	Open record: arylamine N-acetyltransferase (MSNAT), Hydralazine
arylamine N-acetyltransferase (NAT)	Bacteroides sp.	4-aminobenzoic acid	—	0.87	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminobenzoic acid
arylamine N-acetyltransferase (NAT)	Citrobacter amalonaticus	2-aminofluorene	—	0.082	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Citrobacter amalonaticus	5-aminosalicylic acid	—	0.112	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Citrobacter farmeri	2-aminofluorene	—	0.064	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Citrobacter farmeri	4-aminosalicylic acid	—	1.79	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Citrobacter farmeri	5-aminosalicylic acid	—	0.061	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Citrobacter farmeri	sulfamethazine	—	0.07	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), sulfamethazine
arylamine N-acetyltransferase (NAT)	Citrobacter freundii	2-aminofluorene	—	0.165	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Citrobacter freundii	4-aminosalicylic acid	—	2.2	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Citrobacter freundii	5-aminosalicylic acid	—	0.158	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Citrobacter koseri	2-aminofluorene	—	0.096	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Citrobacter koseri	4-aminosalicylic acid	—	0.86	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Citrobacter koseri	5-aminosalicylic acid	—	0.21	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Citrobacter koseri	sulfamethazine	—	0.115	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), sulfamethazine
arylamine N-acetyltransferase (NAT)	Escherichia coli	2-aminofluorene	—	0.127	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Escherichia coli	2-aminofluorene	—	0.205	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Escherichia coli	4-aminosalicylic acid	—	1.24	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Escherichia coli	4-aminosalicylic acid	—	1.16	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Escherichia coli	5-aminosalicylic acid	—	0.117	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Escherichia coli	sulfamethazine	—	0.059	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), sulfamethazine
arylamine N-acetyltransferase (NAT)	Escherichia coli	sulfamethazine	—	0.121	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), sulfamethazine
arylamine N-acetyltransferase (NAT)	Helicobacter pylori	2-aminofluorene	—	0.106	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Klebsiella oxytoca	2-aminofluorene	—	0.158	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Klebsiella oxytoca	5-aminosalicylic acid	—	0.347	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Klebsiella rhinoscleromatis	2-aminofluorene	—	0.141	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Klebsiella rhinoscleromatis	sulfamethazine	—	0.146	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), sulfamethazine
arylamine N-acetyltransferase (NAT)	Morganella morganii	2-aminofluorene	—	0.117	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Pseudomonas aeruginosa	2-aminofluorene	—	0.044	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Pseudomonas aeruginosa	4-aminobenzoic acid	—	1.2	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminobenzoic acid
arylamine N-acetyltransferase (NAT)	Pseudomonas aeruginosa	4-aminosalicylic acid	—	0.258	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Pseudomonas aeruginosa	5-aminosalicylic acid	—	0.026	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Salmonella enterica serovar Typhimurium	2-aminofluorenecell lysate of the NAT-overproducing strain YG1024	—	0.365	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Salmonella enterica serovar Typhimurium	2-aminofluorenebacterial cell lysate	—	0.397	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Salmonella enterica serovar Typhimurium	2-aminofluorenebacterial cell lysate	—	0.404	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Salmonella enterica serovar Typhimurium	2-aminofluorenebacterial cell lysate	—	0.311	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Salmonella enterica serovar Typhimurium	4-aminobenzoic acid	—	51.6	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 4-aminobenzoic acid
arylamine N-acetyltransferase (NAT)	Salmonella enterica serovar Typhimurium	5-aminosalicylic acid	—	0.208	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (NAT)	Salmonella enterica serovar Typhimurium	sulfamethazine	—	0.283	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), sulfamethazine
arylamine N-acetyltransferase (NAT)	Serratia marcescens	2-aminofluorene	—	0.079	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), 2-aminofluorene
arylamine N-acetyltransferase (NAT)	Serratia marcescens	sulfamethazine	—	0.55	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase (NAT), sulfamethazine
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	1-hydrazinylphthalazine	44	0.61	72	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 1-hydrazinylphthalazine
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	2-amino-4-chlorophenol	21	1.9	11	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 2-amino-4-chlorophenol
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	2-amino-4-methylphenol	70	3.06	23	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 2-amino-4-methylphenol
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	2-aminophenol	51	5.79	8.9	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 2-aminophenol
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	3-amino-4-hydroxybenzoic acid0.1 mM DTNB; AcCoA fixed at 0.8 mM; amine substrate varied	94	0.32	290	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 3-amino-4-hydroxybenzoic acid
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	3-amino-4-hydroxybenzoic acidcontinuous DTNB assay; cosubstrate AcCoA (varied)	154	0.836	184 calc.	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 3-amino-4-hydroxybenzoic acid
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	4-amino-3-hydroxybenzoic acid	66	0.9	73	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 4-amino-3-hydroxybenzoic acid
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	4-aminobenzoic acid	0.7	5	0.15	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 4-aminobenzoic acid
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	4-chloroaniline	0.2	6	0.038	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 4-chloroaniline
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	4-fluoroaniline	0.9	51	0.012	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 4-fluoroaniline
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	4-hydroxybenzohydrazide	10.9	20	0.55	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 4-hydroxybenzohydrazide
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	4-methylaniline	0.8	11	0.076	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), 4-methylaniline
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	5-aminosalicylic acid	0.017	1	0.018	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (TBNAT), 5-aminosalicylic acid
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	acetyl coenzyme A0.1 mM DTNB; AHB fixed at 1.5 mM; (AHB, 1.5 mM)	—	0.14	—	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), acetyl coenzyme A
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	acetyl coenzyme Acontinuous DTNB assay; (AHB, varied)	—	0.358	—	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), acetyl coenzyme A
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	acetyl coenzyme A	—	0.56	—	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (TBNAT), acetyl coenzyme A
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	aniline	0.28	23	0.017	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), aniline
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	anisidine	2.9	14	0.21	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), anisidine
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	benzohydrazide	1.9	14	0.14	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), benzohydrazide
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	hydralazine	0.02	0.68	0.0294	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (TBNAT), hydralazine
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	pyridine-3-carbohydrazide	0.6	14	0.045	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), pyridine-3-carbohydrazide
arylamine N-acetyltransferase (TBNAT)	Mycobacterium tuberculosis	pyridine-4-carbohydrazide	4.9	102	0.049	pH 7.7, 25 °C	PMID 18795795	Open record: arylamine N-acetyltransferase (TBNAT), pyridine-4-carbohydrazide
arylamine N-acetyltransferase (TBNAT)chimera TB12MM3	Mycobacterium tuberculosis	4-anisidine	0.6	2.3	0.26	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (TBNAT) chimera TB12MM3, 4-anisidine
arylamine N-acetyltransferase (TBNAT)chimera TB12MM3	Mycobacterium tuberculosis	5-aminosalicylic acid	1.8	1.2	1.5	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (TBNAT) chimera TB12MM3, 5-aminosalicylic acid
arylamine N-acetyltransferase (TBNAT)chimera TB12MM3	Mycobacterium tuberculosis	acetyl coenzyme A	—	0.07	—	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (TBNAT) chimera TB12MM3, acetyl coenzyme A
arylamine N-acetyltransferase (TBNAT)chimera TB12MM3	Mycobacterium tuberculosis	isoniazid	0.1	4.7	0.121	pH 8	PMID 19636684	Open record: arylamine N-acetyltransferase (TBNAT) chimera TB12MM3, isoniazid
arylamine N-acetyltransferase 1 (NAT1)	Homo sapiens	5-aminosalicylic acid	—	0.0067	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase 1 (NAT1), 5-aminosalicylic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	AcCoAPNA acetylation followed at 430; cosubstrate PNA	—	1.49	0.17	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, AcCoA
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	AcCoAresidual PABA quantified as the DMAB Schiff base at 450	—	2.7	3	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, AcCoA
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	anisidine	28	0.25	114	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, anisidine
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	p-aminobenzoic acidPNPA as acetyl donor; MOPS buffer 100 mM; 150 mM NaCl	38	0.11	345	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, p-aminobenzoic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	p-aminobenzoic acidAcCoA as acetyl donor; dimethylglutaric acid buffer 50 mM	8.14	0.28	29	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, p-aminobenzoic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	p-aminobenzoyl-glutamic acid	16	6.2	2.6	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, p-aminobenzoyl-glutamic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; Table 2	—	7.4	3.8	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; cosubstrate PABA	—	7.5	5	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; Table 2	—	5.6	2.8	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	p-nitrophenyl acetatesingle-turnover stopped-flow acetylation by PNPA; 3% DMSO	—	2.8	—	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190A	hamster	PNA	0.25	2.92	0.087	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190A, PNA
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	AcCoAPNA acetylation followed at 430; cosubstrate PNA	—	0.14	2.23	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, AcCoA
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	AcCoAresidual PABA quantified as the DMAB Schiff base at 450	—	1.8	106	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, AcCoA
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	anisidine	288	0.58	496	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, anisidine
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	p-aminobenzoic acidPNPA as acetyl donor; MOPS buffer 100 mM; 150 mM NaCl	393	0.22	1786	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, p-aminobenzoic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	p-aminobenzoic acidAcCoA as acetyl donor; dimethylglutaric acid buffer 50 mM	189	0.14	1.36 × 10³	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, p-aminobenzoic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	p-aminobenzoyl-glutamic acid	86	2.5	34	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, p-aminobenzoyl-glutamic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; Table 2	—	7.8	37	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; cosubstrate PABA	—	7.7	51	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; Table 2	—	2.8	30	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	p-nitrophenyl acetatesingle-turnover stopped-flow acetylation by PNPA; 3% DMSO	—	3.5	—	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190F	hamster	PNA	0.31	0.48	0.66	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190F, PNA
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	AcCoAPNA acetylation followed at 430; cosubstrate PNA	—	0.71	1.26	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, AcCoA
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	AcCoAresidual PABA quantified as the DMAB Schiff base at 450	—	1.9	30	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, AcCoA
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	anisidine	85	0.18	483	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, anisidine
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	p-aminobenzoic acidPNPA as acetyl donor; MOPS buffer 100 mM; 150 mM NaCl	60	0.08	746	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, p-aminobenzoic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	p-aminobenzoic acidAcCoA as acetyl donor; dimethylglutaric acid buffer 50 mM	58	0.06	974	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, p-aminobenzoic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	p-aminobenzoyl-glutamic acid	77	2.7	28	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, p-aminobenzoyl-glutamic acid
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; Table 2	—	10.1	8.4	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; cosubstrate PABA	—	4.5	13	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	p-nitrophenyl acetatePNPA as acetyl donor; 0.1 mM DTT; 4% DMSO; Table 2	—	11	7	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	p-nitrophenyl acetatesingle-turnover stopped-flow acetylation by PNPA; 3% DMSO	—	4.1	—	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, p-nitrophenyl acetate
arylamine N-acetyltransferase 2 (NAT2)variant Y190I	hamster	PNA	0.89	1.51	0.6	pH 7, 25 °C	PMID 19860825	Open record: arylamine N-acetyltransferase 2 (NAT2) variant Y190I, PNA
arylamine N-acetyltransferase 2 (NAT2)	Homo sapiens	5-aminosalicylic acid	—	0.184	—	37 °C	PMID 11344150	Open record: arylamine N-acetyltransferase 2 (NAT2), 5-aminosalicylic acid
hamster NAT2	hamster	2-methylaniline	4.8	1.1	4.2	pH 7, 23 °C	PMID 16959263	Open record: hamster NAT2, 2-methylaniline
hamster NAT2	hamster	4-amino-3-methylbenzoic acid	14.2	0.18	78.7	pH 7, 23 °C	PMID 16959263	Open record: hamster NAT2, 4-amino-3-methylbenzoic acid
human NAT1	Homo sapiens	2,3-dimethylaniline	27	1.11	24	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 2,3-dimethylaniline
human NAT1	Homo sapiens	2,4-dimethylaniline	67	2.06	32	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 2,4-dimethylaniline
human NAT1	Homo sapiens	2,5-dimethylaniline	5.7	6.73	0.85	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 2,5-dimethylaniline
human NAT1	Homo sapiens	2-aminofluorene	449	0.109	4.12 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 2-aminofluorene
human NAT1	Homo sapiens	2-methylaniline	6.3	1.2	5	pH 7, 23 °C	PMID 16959263	Open record: human NAT1, 2-methylaniline
human NAT1	Homo sapiens	2-methylaniline	12	2.32	5.2	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 2-methylaniline
human NAT1	Homo sapiens	3,4-dimethylaniline	461	0.352	1.31 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 3,4-dimethylaniline
human NAT1	Homo sapiens	3,5-dimethylaniline	308	0.742	415	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 3,5-dimethylaniline
human NAT1	Homo sapiens	3-ethylaniline	310	0.576	538	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 3-ethylaniline
human NAT1	Homo sapiens	4-amino-3-methylbenzoic acid	16.6	0.17	96.8	pH 7, 23 °C	PMID 16959263	Open record: human NAT1, 4-amino-3-methylbenzoic acid
human NAT1	Homo sapiens	4-aminobiphenyl	243	0.191	1.27 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 4-aminobiphenyl
human NAT1	Homo sapiens	4-ethylaniline	430	0.205	2.1 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 4-ethylaniline
human NAT1	Homo sapiens	4-methylaniline	303	0.483	627	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, 4-methylaniline
human NAT1	Homo sapiens	aniline	281	2.49	113	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, aniline
human NAT1	Homo sapiens	p-aminobenzoic acid	298	0.084	3.55 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, p-aminobenzoic acid
human NAT1	Homo sapiens	p-aminosalicylic acid	591	0.059	1 × 10⁴	pH 7, 37 °C	PMID 17672512	Open record: human NAT1, p-aminosalicylic acid
human NAT2	Homo sapiens	2,3-dimethylaniline	256	5.53	46	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 2,3-dimethylaniline
human NAT2	Homo sapiens	2,4-dimethylaniline	661	5.03	131	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 2,4-dimethylaniline
human NAT2	Homo sapiens	2,5-dimethylaniline	313	3.12	100	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 2,5-dimethylaniline
human NAT2	Homo sapiens	2-aminofluorene	759	0.286	2.65 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 2-aminofluorene
human NAT2	Homo sapiens	2-ethylaniline	61	2.11	29	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 2-ethylaniline
human NAT2	Homo sapiens	2-methylaniline	72	6.6	10.8	pH 7, 23 °C	PMID 16959263	Open record: human NAT2, 2-methylaniline
human NAT2	Homo sapiens	2-methylaniline	111	7.18	15	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 2-methylaniline
human NAT2	Homo sapiens	3,4-dimethylaniline	800	0.688	1.16 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 3,4-dimethylaniline
human NAT2	Homo sapiens	3,5-dimethylaniline	1.22 × 10³	0.28	4.36 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 3,5-dimethylaniline
human NAT2	Homo sapiens	3-ethylaniline	1.96 × 10³	1.32	1.49 × 10³	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 3-ethylaniline
human NAT2	Homo sapiens	4-amino-3-methylbenzoic acid	1.3	11	0.11	pH 7, 23 °C	PMID 16959263	Open record: human NAT2, 4-amino-3-methylbenzoic acid
human NAT2	Homo sapiens	4-aminobiphenyl	256	0.486	527	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 4-aminobiphenyl
human NAT2	Homo sapiens	4-ethylaniline	700	3.27	214	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 4-ethylaniline
human NAT2	Homo sapiens	4-methylaniline	1.6 × 10³	11.8	136	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, 4-methylaniline
human NAT2	Homo sapiens	aniline	711	11.2	63	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, aniline
human NAT2	Homo sapiens	p-aminobenzoic acid	38	152	0.25	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, p-aminobenzoic acid
human NAT2	Homo sapiens	p-aminosalicylic acid	27	5.39	5	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, p-aminosalicylic acid
human NAT2	Homo sapiens	sulfamethazine	387	5.39	72	pH 7, 37 °C	PMID 17672512	Open record: human NAT2, sulfamethazine
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	2-aminophenol	—	1.94	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), 2-aminophenol
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	2-methoxyaniline	—	0.41	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), 2-methoxyaniline
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	3-aminophenol	—	1.71	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), 3-aminophenol
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	4-aminobenzoic acid	—	0.36	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), 4-aminobenzoic acid
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	4-aminophenol	—	0.54	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), 4-aminophenol
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	4-ethoxyaniline	—	0.89	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), 4-ethoxyaniline
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	4-methoxyaniline	—	0.83	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), 4-methoxyaniline
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	4-methylaniline	—	0.63	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), 4-methylaniline
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	aniline	—	0.55	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), aniline
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	anthranilic acid (2-aminobenzoic acid)	—	0.48	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), anthranilic acid (2-aminobenzoic acid)
N-hydroxyarylamine O-acetyltransferase (HNhoA)	Escherichia coli	isonicotinic acid hydrazide	—	0.59	—	pH 7.4, 37 °C	PMID 10806332	Open record: N-hydroxyarylamine O-acetyltransferase (HNhoA), isonicotinic acid hydrazide
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	2-amino-4-chlorophenol	0.27	0.81	0.34	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), 2-amino-4-chlorophenol
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	2-amino-4-methylphenol	1.3	1.9	0.65	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), 2-amino-4-methylphenol
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	2-aminophenol	0.41	1.4	0.28	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), 2-aminophenol
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	3-amino-4-hydroxybenzaldehyde	0.29	2.6	0.1	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), 3-amino-4-hydroxybenzaldehyde
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	3-amino-4-hydroxybenzenesulfonic acid	1.1	12	0.089	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), 3-amino-4-hydroxybenzenesulfonic acid
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	3-amino-4-hydroxybenzoic acid	1.3	2	0.63	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), 3-amino-4-hydroxybenzoic acid
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	4-amino-3-hydroxybenzoic acid	0.0093	2.2	0.0039	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), 4-amino-3-hydroxybenzoic acid
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	5-aminosalicylic acid	0.011	0.84	0.01	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), 5-aminosalicylic acid
SgNAT (arylamine N-acetyltransferase)	Streptomyces griseus	isoniazid	0.024	3.7	0.0061	pH 7, 30 °C	PMID 17158669	Open record: SgNAT (arylamine N-acetyltransferase), isoniazid