EC 2.3.1.82: aminoglycoside 6'-N-acetyltransferase

TransferasesOpen in Browse

CatLog read 134 records for EC 2.3.1.82 from 6 papers, for 4 organisms. Names in these papers: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)), ANT(3″)-Ii/AAC(6′)-IId, AAC(6')-Ig and 3 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 141 records for EC 2.3.1.82 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.82 in Browse.

Papers

Papers with records for EC 2.3.1.82
Paper	Organisms	Records
Molecular mechanism of the enterococcal aminoglycoside 6'-N-acetyltransferase': role of GNAT-conserved residues in the chemistry of antibiotic inactivation	Enterococcus faecium	39
Domain dissection and characterization of the aminoglycoside resistance enzyme ANT(3″)-Ii/AAC(6')-IId from Serratia marcescens	Serratia marcescens	26
The molecular basis of the expansive substrate specificity of the antibiotic resistance enzyme aminoglycoside acetyltransferase-6'-aminoglycoside phosphotransferase-2". The role of ASP-99 as an…	—	21
Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia	Stenotrophomonas maltophilia	18
Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes	Acinetobacter haemolyticus	16
Overexpression and characterization of the chromosomal aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium	Enterococcus faecium	14

Records

Records for EC 2.3.1.82 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
AAC(6')-Iak	Stenotrophomonas maltophilia	amikacin	0.11	0.032	4		PMID 25092711	Open record: AAC(6')-Iak, amikacin
AAC(6')-Iak	Stenotrophomonas maltophilia	arbekacin	0.57	0.036	16		PMID 25092711	Open record: AAC(6')-Iak, arbekacin
AAC(6')-Iak	Stenotrophomonas maltophilia	dibekacin	0.25	0.024	10		PMID 25092711	Open record: AAC(6')-Iak, dibekacin
AAC(6')-Iak	Stenotrophomonas maltophilia	isepamicin	0.05	0.044	1		PMID 25092711	Open record: AAC(6')-Iak, isepamicin
AAC(6')-Iak	Stenotrophomonas maltophilia	kanamycin	0.04	0.03	1		PMID 25092711	Open record: AAC(6')-Iak, kanamycin
AAC(6')-Iak	Stenotrophomonas maltophilia	neomycin	0.32	0.01	34		PMID 25092711	Open record: AAC(6')-Iak, neomycin
AAC(6')-Iak	Stenotrophomonas maltophilia	netilmicin	0.3	0.07	4		PMID 25092711	Open record: AAC(6')-Iak, netilmicin
AAC(6')-Iak	Stenotrophomonas maltophilia	sisomicin	0.16	0.004	38		PMID 25092711	Open record: AAC(6')-Iak, sisomicin
AAC(6')-Iak	Stenotrophomonas maltophilia	tobramycin	0.08	0.016	6		PMID 25092711	Open record: AAC(6')-Iak, tobramycin
AAC(6')-Ig	Acinetobacter haemolyticus	2′-N-ethyl netilmicin	0.097	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, 2′-N-ethyl netilmicin
AAC(6')-Ig	Acinetobacter haemolyticus	amikacin	0.328	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, amikacin
AAC(6')-Ig	Acinetobacter haemolyticus	amikacin	0.382	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, amikacin
AAC(6')-Ig	Acinetobacter haemolyticus	arbekacin	0.077	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, arbekacin
AAC(6')-Ig	Acinetobacter haemolyticus	butirosin A	0.107	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, butirosin A
AAC(6')-Ig	Acinetobacter haemolyticus	butirosin A	0.21	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, butirosin A
AAC(6')-Ig	Acinetobacter haemolyticus	dibekacin	0.127	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, dibekacin
AAC(6')-Ig	Acinetobacter haemolyticus	gentamicin	0.055	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, gentamicin
AAC(6')-Ig	Acinetobacter haemolyticus	isepamicin	0.779	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, isepamicin
AAC(6')-Ig	Acinetobacter haemolyticus	isepamicin	1.56	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, isepamicin
AAC(6')-Ig	Acinetobacter haemolyticus	kanamycin B	0.181	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, kanamycin B
AAC(6')-Ig	Acinetobacter haemolyticus	kanamycin B	0.352	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, kanamycin B
AAC(6')-Ig	Acinetobacter haemolyticus	neomycin C	0.057	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, neomycin C
AAC(6')-Ig	Acinetobacter haemolyticus	ribostamycin	0.072	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, ribostamycin
AAC(6')-Ig	Acinetobacter haemolyticus	sisomicin	0.13	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, sisomicin
AAC(6')-Ig	Acinetobacter haemolyticus	tobramycin	0.085	—	—	pH 8, 37 °C	PMID 27785912	Open record: AAC(6')-Ig, tobramycin
AAC(6')-Iz	Stenotrophomonas maltophilia	amikacin	0.26	0.024	11		PMID 25092711	Open record: AAC(6')-Iz, amikacin
AAC(6')-Iz	Stenotrophomonas maltophilia	arbekacin	0.57	0.017	36		PMID 25092711	Open record: AAC(6')-Iz, arbekacin
AAC(6')-Iz	Stenotrophomonas maltophilia	dibekacin	0.46	0.031	15		PMID 25092711	Open record: AAC(6')-Iz, dibekacin
AAC(6')-Iz	Stenotrophomonas maltophilia	isepamicin	0.11	0.049	2		PMID 25092711	Open record: AAC(6')-Iz, isepamicin
AAC(6')-Iz	Stenotrophomonas maltophilia	kanamycin	0.05	0.044	1		PMID 25092711	Open record: AAC(6')-Iz, kanamycin
AAC(6')-Iz	Stenotrophomonas maltophilia	neomycin	0.29	0.013	23		PMID 25092711	Open record: AAC(6')-Iz, neomycin
AAC(6')-Iz	Stenotrophomonas maltophilia	netilmicin	0.34	0.025	13		PMID 25092711	Open record: AAC(6')-Iz, netilmicin
AAC(6')-Iz	Stenotrophomonas maltophilia	sisomicin	0.2	0.007	28		PMID 25092711	Open record: AAC(6')-Iz, sisomicin
AAC(6')-Iz	Stenotrophomonas maltophilia	tobramycin	0.25	0.012	21		PMID 25092711	Open record: AAC(6')-Iz, tobramycin
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))	—	fortimicin A	0.28	0.0254	11	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)), fortimicin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))	—	neamine	0.43	0.0783	5.6	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)), neamine
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))	—	paromomycin	0.059	0.324	0.18	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)), paromomycin
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99A	—	acetyl-CoA	0.035	0.0453	0.79	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99A, acetyl-CoA
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99A	—	fortimicin A	2 × 10⁻⁴	—	—	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99A, fortimicin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99A	—	kanamycin A	0.033	0.126	0.26	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99A, kanamycin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99A	—	neamine	0.029	0.443	0.065	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99A, neamine
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99E	—	acetyl-CoA	0.11	0.017	6.5	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99E, acetyl-CoA
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99E	—	fortimicin A	0.006	0.07	0.082	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99E, fortimicin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99E	—	kanamycin A	0.19	0.102	1.8	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99E, kanamycin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99E	—	neamine	0.066	0.229	0.29	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99E, neamine
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99E	—	paromomycin	4 × 10⁻⁴	—	—	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99E, paromomycin
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99N	—	acetyl-CoA	0.17	0.0399	4.4	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99N, acetyl-CoA
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99N	—	fortimicin A	8 × 10⁻⁴	—	—	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99N, fortimicin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99N	—	kanamycin A	0.038	0.0902	0.43	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99N, kanamycin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant D99N	—	neamine	0.028	0.509	0.055	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant D99N, neamine
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant Y96F	—	acetyl-CoA	1.3	0.0736	18	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant Y96F, acetyl-CoA
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant Y96F	—	fortimicin A	0.45	0.0435	10	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant Y96F, fortimicin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant Y96F	—	kanamycin A	1.1	0.079	13	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant Y96F, kanamycin A
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant Y96F	—	neamine	1.3	0.326	3.9	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant Y96F, neamine
AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″))variant Y96F	—	paromomycin	0.026	0.771	0.033	pH 7.5, 37 °C	PMID 12566434	Open record: AAC(6′)-Ie (aminoglycoside 6′-N/O-acetyltransferase domain of bifunctional AAC(6′)-APH(2″)) variant Y96F, paromomycin
AAC(6′)-IId	Serratia marcescens	acetyl-CoA	12.1	0.147	82	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, acetyl-CoA
AAC(6′)-IId	Serratia marcescens	amikacin	7.09	0.127	62.4	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, amikacin
AAC(6′)-IId	Serratia marcescens	gentamicin	3.33	0.0143	234	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, gentamicin
AAC(6′)-IId	Serratia marcescens	kanamycin A	2.13	0.016	133	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, kanamycin A
AAC(6′)-IId	Serratia marcescens	neomycin B	11.1	0.0321	346	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, neomycin B
AAC(6′)-IId	Serratia marcescens	netilmicin	3.21	0.00387	829	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, netilmicin
AAC(6′)-IId	Serratia marcescens	ribostamycin	5.7	0.0693	82.2	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, ribostamycin
AAC(6′)-IId	Serratia marcescens	sisomicin	5.35	0.00492	1.09 × 10³	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, sisomicin
AAC(6′)-IId	Serratia marcescens	tobramycin	3.73	0.0148	252	pH 7.5	PMID 23485681	Open record: AAC(6′)-IId, tobramycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	acetyl coenzyme A	0.403	0.0235	17	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, acetyl coenzyme A
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Amikacin	0.106	0.0131	8.1	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Amikacin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Butirosin	0.466	0.014	33	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Butirosin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Dibekacin	0.632	0.036	17	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Dibekacin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Gentamicin B	0.388	0.0223	17	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Gentamicin B
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Kanamycin A	0.816	0.0199	46	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Kanamycin A
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Kanamycin B	1.08	0.0189	57	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Kanamycin B
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Neamine	0.419	0.00582	72	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Neamine
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Neomycin C	0.205	0.00531	39	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Neomycin C
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Netilmicin	0.512	0.00638	80	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Netilmicin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	propionyl coenzyme A	0.317	0.0195	16	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, propionyl coenzyme A
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Ribostamycin	0.338	0.00908	37	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Ribostamycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Sisomicin	0.37	0.0117	32	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Sisomicin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii	Enterococcus faecium	Tobramycin	1.11	0.022	51	pH 6, 37 °C	PMID 9145851	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii, Tobramycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant E72A	Enterococcus faecium	acetyl-CoA	0.99	0.154	6.4	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant E72A, acetyl-CoA
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant E72A	Enterococcus faecium	amikacin	0.05	0.38	0.13	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant E72A, amikacin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant E72A	Enterococcus faecium	kanamycin A	0.55	3.49	0.16	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant E72A, kanamycin A
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant E72A	Enterococcus faecium	neamine	0.44	0.482	0.91	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant E72A, neamine
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant E72A	Enterococcus faecium	neomycin	1.1	0.029	38	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant E72A, neomycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant E72A	Enterococcus faecium	ribostamycin	0.35	0.301	1.2	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant E72A, ribostamycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant E72A	Enterococcus faecium	tobramycin	1.1	1.15	0.96	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant E72A, tobramycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant H74A	Enterococcus faecium	acetyl-CoA	0.18	0.0073	25	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant H74A, acetyl-CoA
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant H74A	Enterococcus faecium	amikacin	0.04	0.0582	0.71	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant H74A, amikacin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant H74A	Enterococcus faecium	kanamycin A	0.05	0.0144	3.3	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant H74A, kanamycin A
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant H74A	Enterococcus faecium	neamine	0.15	0.0432	3.5	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant H74A, neamine
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant H74A	Enterococcus faecium	neomycin	0.19	0.0182	10	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant H74A, neomycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant H74A	Enterococcus faecium	ribostamycin	0.23	0.0381	6	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant H74A, ribostamycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant H74A	Enterococcus faecium	tobramycin	0.3	0.0369	8.2	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant H74A, tobramycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76A	Enterococcus faecium	acetyl-CoA	0.23	0.0033	69	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76A, acetyl-CoA
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76A	Enterococcus faecium	amikacin	0.03	0.0114	2.5	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76A, amikacin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76A	Enterococcus faecium	kanamycin A	0.27	0.0257	11	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76A, kanamycin A
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76A	Enterococcus faecium	neamine	0.38	0.0224	17	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76A, neamine
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76A	Enterococcus faecium	neomycin	0.16	0.019	8.4	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76A, neomycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76A	Enterococcus faecium	ribostamycin	0.15	0.0214	7	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76A, ribostamycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76A	Enterococcus faecium	tobramycin	0.89	0.062	14	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76A, tobramycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76P	Enterococcus faecium	acetyl-CoA	0.06	0.0489	1.2	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76P, acetyl-CoA
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76P	Enterococcus faecium	neamine	0.002	0.0682	0.031	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76P, neamine
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76P	Enterococcus faecium	neomycin	0.04	0.0573	0.65	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76P, neomycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76P	Enterococcus faecium	ribostamycin	0.01	0.107	0.077	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76P, ribostamycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant L76P	Enterococcus faecium	tobramycin	0.01	0.146	0.038	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant L76P, tobramycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147A	Enterococcus faecium	acetyl-CoA	0.01	0.0047	1.6	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147A, acetyl-CoA
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147A	Enterococcus faecium	kanamycin A	0.01	0.11	0.056	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147A, kanamycin A
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147A	Enterococcus faecium	neamine	0.004	0.169	0.022	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147A, neamine
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147A	Enterococcus faecium	neomycin	0.001	0.0386	0.036	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147A, neomycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147A	Enterococcus faecium	ribostamycin	0.02	0.109	0.15	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147A, ribostamycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147A	Enterococcus faecium	tobramycin	0.004	0.147	0.026	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147A, tobramycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147F	Enterococcus faecium	acetyl-CoA	0.07	0.0041	18	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147F, acetyl-CoA
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147F	Enterococcus faecium	amikacin	0.003	2.19	0.0012	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147F, amikacin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147F	Enterococcus faecium	kanamycin A	0.03	0.34	0.1	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147F, kanamycin A
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147F	Enterococcus faecium	neamine	0.05	0.15	0.32	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147F, neamine
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147F	Enterococcus faecium	neomycin	0.07	0.0553	1.3	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147F, neomycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147F	Enterococcus faecium	ribostamycin	0.12	0.306	0.4	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147F, ribostamycin
aminoglycoside 6'-N-acetyltransferase AAC(6')-Iivariant Y147F	Enterococcus faecium	tobramycin	0.1	0.136	0.71	pH 6, 37 °C	PMID 14717599	Open record: aminoglycoside 6'-N-acetyltransferase AAC(6')-Ii variant Y147F, tobramycin
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	acetyl-CoA	1.62	0.215	8.38	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, acetyl-CoA
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	amikacin	2.92	5.56 × 10⁻⁴	5.25 × 10³	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, amikacin
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	ATP	0.753	0.0279	27	pH 7.5, 25 °C	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, ATP
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	CTP	0.531	0.131	4.04	pH 7.5, 25 °C	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, CTP
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	dATP	0.405	0.0209	19.4	pH 7.5, 25 °C	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, dATP
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	dCTP	1.11	0.166	6.7	pH 7.5, 25 °C	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, dCTP
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	dUTP	0.535	0.0747	7.16	pH 7.5, 25 °C	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, dUTP
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	gentamicin	1.11	0.00504	220	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, gentamicin
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	ITP	0.148	0.0306	4.83	pH 7.5, 25 °C	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, ITP
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	kanamycin A	3.81	0.00202	1.89 × 10³	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, kanamycin A
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	neomycin B	9.06	0.023	394	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, neomycin B
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	netilmicin	1.91	0.00177	1.08 × 10³	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, netilmicin
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	ribostamycin	3.88	0.016	243	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, ribostamycin
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	sisomicin	2.93	0.0022	1.33 × 10³	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, sisomicin
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	spectinomycin	0.748	1.59 × 10⁻⁴	4.7 × 10³	pH 7.5, 25 °C	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, spectinomycin
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	tobramycin	3.84	0.00792	485	pH 7.5	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, tobramycin
ANT(3″)-Ii/AAC(6′)-IId	Serratia marcescens	UTP	0.526	0.105	5.02	pH 7.5, 25 °C	PMID 23485681	Open record: ANT(3″)-Ii/AAC(6′)-IId, UTP