CatLogenzyme kinetics catalog

EC 2.5.1.31: ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]

TransferasesOpen in Browse

CatLog read 159 records for EC 2.5.1.31 from 10 papers, for 2 organisms. Names in these papers: undecaprenyl diphosphate synthase (UPP synthase), undecaprenyl pyrophosphate synthase (UPPs), undecaprenyl pyrophosphate synthase (UPPS), undecaprenyl diphosphate (UPP) synthase and 1 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 25 records for EC 2.5.1.31 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.5.1.31 in Browse.

Papers

PaperOrganismsRecords
Identification of Significant residues for homoallylic substrate binding of Micrococcus luteus B-P 26 undecaprenyl diphosphate synthaseMicrococcus luteus30
Mutational analysis of allylic substrate binding site of Micrococcus luteus B-P 26 undecaprenyl diphosphate synthaseMicrococcus luteus26
Significance of Asn-77 and Trp-78 in the catalytic function of undecaprenyl diphosphate synthase of Micrococcus luteus B-P 26Micrococcus luteus21
Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutantsEscherichia coli15
Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthaseEscherichia coli15
Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in…Escherichia coli14
Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysisEscherichia coli12
Effect of site-directed mutagenesis of the conserved aspartate and glutamate on E. coli undecaprenyl pyrophosphate synthase catalysisEscherichia coli10
Significance of highly conserved aromatic residues in Micrococcus luteus B-P 26 undecaprenyl diphosphate synthaseMicrococcus luteus10
Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and tritonEscherichia coli6

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
undecaprenyl diphosphate (UPP) synthaseMicrococcus luteus(E,E)-farnesyl diphosphate1.660.0036460 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthaseMicrococcus luteus(E,E,E)-geranylgeranyl diphosphate—0.0088—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant D29AMicrococcus luteus(E,E)-farnesyl diphosphate0.01670.03320.503 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant D29AMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.02580.0055.2 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant D29AMicrococcus luteusisopentenyl diphosphate—0.0452—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant E76QMicrococcus luteus(E,E)-farnesyl diphosphate0.5050.0023220 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant E76QMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.6040.0023260 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant E76QMicrococcus luteusisopentenyl diphosphate—0.0114—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant E84QMicrococcus luteus(E,E)-farnesyl diphosphate1.090.011495.6 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant E84QMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate1.070.006180 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant E84QMicrococcus luteusisopentenyl diphosphate—0.0307—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant G32RMicrococcus luteus(E,E)-farnesyl diphosphate0.4620.0033140 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant G32RMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.6080.0043140 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant G32RMicrococcus luteusisopentenyl diphosphate—0.006—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant G32R-R42GMicrococcus luteus(E,E)-farnesyl diphosphate0.960.005190 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant G32R-R42GMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate1.110.0059190 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant G32R-R42GMicrococcus luteusisopentenyl diphosphate—0.0059—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R33AMicrococcus luteus(E,E)-farnesyl diphosphate0.05420.1440.376 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R33AMicrococcus luteus(E,E,E)-geranylgeranyl diphosphate—0.064—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R33AMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.08130.00958.6 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R42GMicrococcus luteus(E,E)-farnesyl diphosphate0.2160.004944 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R42GMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.3820.004585 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R42GMicrococcus luteusisopentenyl diphosphate—0.0242—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R80AMicrococcus luteus(E,E)-farnesyl diphosphate0.0040.02310.17 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R80AMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.005790.00610.95 calc.pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate (UPP) synthasevariant R80AMicrococcus luteusisopentenyl diphosphate—0.0491—pH 7.5, 37 °CPMID 12680756Open
undecaprenyl diphosphate synthase (UPP synthase)Micrococcus luteus(all-E)-farnesyl diphosphate—0.0083—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)Micrococcus luteus(Z,E,E)-geranylgeranyl diphosphate1.770.0082220 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)Micrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0082—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)Micrococcus luteusfarnesyl diphosphate1.220.0083150 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)Micrococcus luteusisopentenyl diphosphate1.850.0078240 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)Micrococcus luteusisopentenyl diphosphate1.220.0078160 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant D221AMicrococcus luteus(all-E)-farnesyl diphosphate—0.0035—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant D221AMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0181—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant D221AMicrococcus luteusisopentenyl diphosphate0.4710.017726.6 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant D226AMicrococcus luteus(all-E)-farnesyl diphosphate—0.0112—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant D226AMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0075—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant D226AMicrococcus luteusisopentenyl diphosphate0.9990.01759 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E193QMicrococcus luteus(all-E)-farnesyl diphosphate—0.0066—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E193QMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0081—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E193QMicrococcus luteusisopentenyl diphosphate0.4010.020419.7 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E201QMicrococcus luteus(all-E)-farnesyl diphosphate—0.0116—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E201QMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0177—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E201QMicrococcus luteusisopentenyl diphosphate0.980.018354 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E216QMicrococcus luteus(all-E)-farnesyl diphosphate—0.0054—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E216QMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0058—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant E216QMicrococcus luteusisopentenyl diphosphate0.0670.09090.74 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant F207SMicrococcus luteus(all-E)-farnesyl diphosphate0.0030.02220.14pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant F207SMicrococcus luteusisopentenyl diphosphate0.010.10310.1pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant F73AMicrococcus luteus(all-E)-farnesyl diphosphate—0.0092—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant F73AMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0094—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant F73AMicrococcus luteusisopentenyl diphosphate0.0730.25250.29 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77AMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.002610.01020.256 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77AMicrococcus luteusfarnesyl diphosphate0.001250.01470.0850 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77AMicrococcus luteusisopentenyl diphosphate0.001640.0120.14 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77DMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.004150.0080.52 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77DMicrococcus luteusfarnesyl diphosphate0.002720.01390.196 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77DMicrococcus luteusisopentenyl diphosphate0.004730.0150.32 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77QMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.002310.0050.46 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77QMicrococcus luteusfarnesyl diphosphate0.001550.01040.149 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant N77QMicrococcus luteusisopentenyl diphosphate0.00270.0090.30 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant R197SMicrococcus luteus(all-E)-farnesyl diphosphate—0.018—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant R197SMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.006—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant R197SMicrococcus luteusisopentenyl diphosphate0.0010.05610.018 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant R203SMicrococcus luteus(all-E)-farnesyl diphosphate—0.0136—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant R203SMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0081—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant R203SMicrococcus luteusisopentenyl diphosphate0.0010.06210.016 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant S74AMicrococcus luteus(all-E)-farnesyl diphosphate—0.0096—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant S74AMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate—0.0053—pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant S74AMicrococcus luteusisopentenyl diphosphate0.1010.12680.797 calc.pH 7.3, 37 °CPMID 11346651Open
undecaprenyl diphosphate synthase (UPP synthase)variant W210AMicrococcus luteus(all-E)-farnesyl diphosphate0.0020.00151.3pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant W210AMicrococcus luteusisopentenyl diphosphate0.0020.01750.12pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant W224AMicrococcus luteus(all-E)-farnesyl diphosphate0.0710.12130.6pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant W224AMicrococcus luteusisopentenyl diphosphate0.0710.03562pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78DMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.30.00838 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78DMicrococcus luteusfarnesyl diphosphate0.1510.1550.974 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78DMicrococcus luteusisopentenyl diphosphate0.3970.013130.3 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78IMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate1.370.01972 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78IMicrococcus luteusfarnesyl diphosphate0.4560.04959.21 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78IMicrococcus luteusisopentenyl diphosphate0.7830.014155.5 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78RMicrococcus luteus(Z,E,E)-geranylgeranyl diphosphate0.8990.01560 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78RMicrococcus luteusfarnesyl diphosphate0.4340.12073.60 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant W78RMicrococcus luteusisopentenyl diphosphate0.8030.016548.7 calc.pH 7.5, 37 °CPMID 11098133Open
undecaprenyl diphosphate synthase (UPP synthase)variant Y148FMicrococcus luteus(all-E)-farnesyl diphosphate0.0150.00285pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant Y148FMicrococcus luteusisopentenyl diphosphate0.1150.02295pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant Y71SMicrococcus luteus(all-E)-farnesyl diphosphate0.1110.007714pH 7.5, 30 °CPMID 14769870Open
undecaprenyl diphosphate synthase (UPP synthase)variant Y71SMicrococcus luteusisopentenyl diphosphate0.110.02544.3pH 7.5, 30 °CPMID 14769870Open
undecaprenyl pyrophosphate synthase (UPPS)Escherichia coli(S)-farnesyl thiopyrophosphate3.1 × 10⁻⁷——pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)Escherichia coliall-trans-farnesyl pyrophosphate2.54 × 10⁻⁴6.2 × 10³ calc.pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPs)Escherichia colifarnesyl pyrophosphate0.05 mM MgCl2—0.0015—PMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)Escherichia colifarnesyl pyrophosphate1 mM MgCl2—3.7 × 10⁻⁴—PMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)Escherichia colifarnesyl pyrophosphate3 mM MgCl2—4.4 × 10⁻⁴—PMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)Escherichia colifarnesyl pyrophosphate50 mM MgCl2—0.00157—PMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPS)Escherichia coligeranyl pyrophosphate1.70.03647 calc.pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)Escherichia coliisopentenyl pyrophosphate—0.0041—pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)Escherichia coliisopentenyl pyrophosphatecosubstrate GPP—0.083—pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)Escherichia coliisopentenyl pyrophosphate8.5 × 10⁻⁵——pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPs)Escherichia coliisopentenyl pyrophosphate0.05 mM MgCl21.230.0115107 calc.PMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)Escherichia coliisopentenyl pyrophosphate1 mM MgCl21.980.0097200 calc.PMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)Escherichia coliisopentenyl pyrophosphate3 mM MgCl21.920.0175110 calc.PMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)Escherichia coliisopentenyl pyrophosphate50 mM MgCl2—0.291—PMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)variant D150AEscherichia coliisopentenyl pyrophosphate1.10.2075.3 calc.pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant D150AEscherichia colitrans,trans-farnesyl pyrophosphate—4 × 10⁻⁴—pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant D218AEscherichia coliisopentenyl pyrophosphate0.220.004450 calc.pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant D218AEscherichia colitrans,trans-farnesyl pyrophosphate—4 × 10⁻⁴—pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant D26AEscherichia coliisopentenyl pyrophosphate0.00330.01410.23 calc.pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant D26AEscherichia colitrans,trans-farnesyl pyrophosphate—5 × 10⁻⁴—pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant D26EEscherichia colifarnesyl pyrophosphate—6.7 × 10⁻⁴—pH 7.5, 25 °CPMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)variant D26EEscherichia coliisopentenyl pyrophosphate3.66 × 10⁻⁴0.02080.0176 calc.pH 7.5, 25 °CPMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)variant D26KEscherichia colifarnesyl pyrophosphate—4.6 × 10⁻⁴—pH 7.5, 25 °CPMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)variant D26KEscherichia coliisopentenyl pyrophosphate7.66 × 10⁻⁵0.00920.0083 calc.pH 7.5, 25 °CPMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)variant D26REscherichia colifarnesyl pyrophosphate—5.5 × 10⁻⁴—pH 7.5, 25 °CPMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)variant D26REscherichia coliisopentenyl pyrophosphate6.33 × 10⁻⁵0.02230.00284 calc.pH 7.5, 25 °CPMID 15788389Open
undecaprenyl pyrophosphate synthase (UPPs)variant E213AEscherichia coliisopentenyl pyrophosphate0.0260.280.093 calc.pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant E213AEscherichia colitrans,trans-farnesyl pyrophosphate—7 × 10⁻⁴—pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant E73AEscherichia coliisopentenyl pyrophosphate0.30.016219 calc.pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPs)variant E73AEscherichia colitrans,trans-farnesyl pyrophosphate—4 × 10⁻⁴—pH 7.5, 25 °CPMID 11076526Open
undecaprenyl pyrophosphate synthase (UPPS)variant F89AEscherichia coliall-trans-geranylgeranyl pyrophosphate0.70.001700 calc.pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant F89AEscherichia colifarnesyl pyrophosphate0.610.0026230 calc.pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant F89AEscherichia coliisopentenyl pyrophosphatecosubstrate FPP—0.084—pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant F89AEscherichia coliisopentenyl pyrophosphatecosubstrate GGPP—0.018—pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPs)variant H199AEscherichia colifarnesyl pyrophosphate—2.8 × 10⁻⁴—pH 7.5, 25 °CPMID 12756244Open
undecaprenyl pyrophosphate synthase (UPPs)variant H199AEscherichia coliisopentenyl pyrophosphate2.20.016140 calc.pH 7.5, 25 °CPMID 12756244Open
undecaprenyl pyrophosphate synthase (UPPs)variant H199A/E213AEscherichia colifarnesyl pyrophosphate—6.6 × 10⁻⁴—pH 7.5, 25 °CPMID 12756244Open
undecaprenyl pyrophosphate synthase (UPPs)variant H199A/E213AEscherichia coliisopentenyl pyrophosphate0.00250.2790.0090 calc.pH 7.5, 25 °CPMID 12756244Open
undecaprenyl pyrophosphate synthase (UPPs)variant H43AEscherichia colifarnesyl pyrophosphate—0.003—pH 7.5, 25 °CPMID 12756244Open
undecaprenyl pyrophosphate synthase (UPPs)variant H43AEscherichia coliisopentenyl pyrophosphate0.00260.0630.041 calc.pH 7.5, 25 °CPMID 12756244Open
undecaprenyl pyrophosphate synthase (UPPS)variant L85AEscherichia coliall-trans-geranylgeranyl pyrophosphate0.180.0012150 calc.pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant L85AEscherichia colifarnesyl pyrophosphate0.0950.001659 calc.pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant L85AEscherichia coliisopentenyl pyrophosphatecosubstrate FPP—0.617—pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant L85AEscherichia coliisopentenyl pyrophosphatecosubstrate GGPP—0.06—pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant L88AEscherichia coliall-trans-geranylgeranyl pyrophosphate0.327 × 10⁻⁴460 calc.pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant L88AEscherichia colifarnesyl pyrophosphate0.230.0021110 calc.pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant L88AEscherichia coliisopentenyl pyrophosphatecosubstrate FPP—0.173—pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant L88AEscherichia coliisopentenyl pyrophosphatecosubstrate GGPP—0.042—pH 7.5, 25 °CPMID 15447632Open
undecaprenyl pyrophosphate synthase (UPPS)variant W149FEscherichia coliall-trans-farnesyl pyrophosphate1.77 × 10⁻⁴2.4 × 10³ calc.pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W149FEscherichia coliisopentenyl pyrophosphate—0.02—pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W207FEscherichia coliall-trans-farnesyl pyrophosphate1.50.0034440 calc.pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W207FEscherichia coliisopentenyl pyrophosphate—0.023—pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W221FEscherichia coliall-trans-farnesyl pyrophosphate3.55 × 10⁻⁴7.0 × 10³ calc.pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W221FEscherichia coliisopentenyl pyrophosphate—0.014—pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W31FEscherichia coliall-trans-farnesyl pyrophosphate1.10.002550 calc.pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W31FEscherichia coliisopentenyl pyrophosphate—0.0059—pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W75FEscherichia coliall-trans-farnesyl pyrophosphate1.10.0018610 calc.pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W75FEscherichia coliisopentenyl pyrophosphate—0.026—pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W91FEscherichia coliall-trans-farnesyl pyrophosphate2.54 × 10⁻⁴6.2 × 10³ calc.pH 7.5, 25 °CPMID 11744728Open
undecaprenyl pyrophosphate synthase (UPPS)variant W91FEscherichia coliisopentenyl pyrophosphate—0.0072—pH 7.5, 25 °CPMID 11744728Open
undecaprenyl-pyrophosphate synthase (UPPs)Escherichia colifarnesyl pyrophosphate—4 × 10⁻⁴—pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)Escherichia coliisopentenyl pyrophosphate2.50.0041610 calc.pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant E81AEscherichia colifarnesyl pyrophosphate—4 × 10⁻⁴—pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant E81AEscherichia coliisopentenyl pyrophosphate0.40.0884.5 calc.pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant N74AEscherichia colifarnesyl pyrophosphate—4 × 10⁻⁴—pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant N74AEscherichia coliisopentenyl pyrophosphate0.0220.0082.8 calc.pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant R77AEscherichia colifarnesyl pyrophosphate—0.0016—pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant R77AEscherichia coliisopentenyl pyrophosphate1.4 × 10⁻⁴0.01570.0089 calc.pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant S71AEscherichia colifarnesyl pyrophosphate—0.001—pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant S71AEscherichia coliisopentenyl pyrophosphate0.110.1330.83 calc.pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant W75AEscherichia colifarnesyl pyrophosphate—0.0032—pH 7.5, 25 °CPMID 11581264Open
undecaprenyl-pyrophosphate synthase (UPPs)variant W75AEscherichia coliisopentenyl pyrophosphate1.10.04624 calc.pH 7.5, 25 °CPMID 11581264Open