EC 3.1.3.16: protein-serine/threonine phosphatase
HydrolasesOpen in Browse
CatLog read 73 records for EC 3.1.3.16 from 4 papers, for 2 organisms. Names in these papers: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), MptpB, PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain, PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain and 2 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 101 records for EC 3.1.3.16 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.1.3.16 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5 | Homo sapiens | 39 |
| MptpB, a virulence factor from Mycobacterium tuberculosis, exhibits triple-specificity phosphatase activity | Mycobacterium tuberculosis | 19 |
| Biochemical characterization of the phosphatase domain of the tumor suppressor PH domain leucine-rich repeat protein phosphatase | Homo sapiens | 12 |
| Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution | Homo sapiens | 3 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| MptpB | Mycobacterium tuberculosis | 4-nitrophenyl phosphate | 134.7 | 0.17 | 791 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, 4-nitrophenyl phosphate |
| MptpB | Mycobacterium tuberculosis | adenosine 5′-monophosphate | 60.97 | 1.749 | 35 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, adenosine 5′-monophosphate |
| MptpB | Mycobacterium tuberculosis | DADEpYLIPQQG | 158.3 | 0.327 | 484 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, DADEpYLIPQQG |
| MptpB | Mycobacterium tuberculosis | dioctanoyl phosphatidylinositol 3,5-bisphosphate (diC8-PtdIns(3,5)P2) | 75.4 | 0.028 | 2723 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, dioctanoyl phosphatidylinositol 3,5-bisphosphate (diC8-PtdIns(3,5)P2) |
| MptpB | Mycobacterium tuberculosis | dioctanoyl phosphatidylinositol 3-phosphate (diC8-PtdIns3P) | 38.5 | 0.018 | 2148 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, dioctanoyl phosphatidylinositol 3-phosphate (diC8-PtdIns3P) |
| MptpB | Mycobacterium tuberculosis | dioctanoyl phosphatidylinositol 4-phosphate (diC8-PtdIns4P) | 100.3 | 0.074 | 1.35 × 10³ | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, dioctanoyl phosphatidylinositol 4-phosphate (diC8-PtdIns4P) |
| MptpB | Mycobacterium tuberculosis | dioctanoyl phosphatidylinositol 5-phosphate (diC8-PtdIns5P) | 80.5 | 0.064 | 1266 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, dioctanoyl phosphatidylinositol 5-phosphate (diC8-PtdIns5P) |
| MptpB | Mycobacterium tuberculosis | inosine 5′-monophosphate | 88.4 | 1.196 | 74 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, inosine 5′-monophosphate |
| MptpB | Mycobacterium tuberculosis | KRpTIRR | 9.12 | 0.076 | 120 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, KRpTIRR |
| MptpB | Mycobacterium tuberculosis | phosphoserine | 18.32 | 0.44 | 41 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, phosphoserine |
| MptpB | Mycobacterium tuberculosis | phosphothreonine | 12.5 | 0.253 | 50 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, phosphothreonine |
| MptpB | Mycobacterium tuberculosis | phosphotyrosine | 60 | 0.291 | 206 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, phosphotyrosine |
| MptpB | Mycobacterium tuberculosis | RRApSVA | 18.08 | 0.078 | 232 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, RRApSVA |
| MptpB | Mycobacterium tuberculosis | TRDIpYETDYYRK | 159.6 | 0.217 | 736 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB, TRDIpYETDYYRK |
| MptpBvariant K164A | Mycobacterium tuberculosis | 4-nitrophenyl phosphate | 163.9 | 0.087 | 1.88 × 10³ | pH 6, 37 °C | PMID 17584180 | Open record: MptpB variant K164A, 4-nitrophenyl phosphate |
| MptpBvariant K164A | Mycobacterium tuberculosis | dioctanoyl phosphatidylinositol 3,5-bisphosphate (diC8-PtdIns(3,5)P2) | 12.7 | 0.022 | 579 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB variant K164A, dioctanoyl phosphatidylinositol 3,5-bisphosphate (diC8-PtdIns(3,5)P2) |
| MptpBvariant K164A | Mycobacterium tuberculosis | dioctanoyl phosphatidylinositol 3-phosphate (diC8-PtdIns3P) | 14.6 | 0.0055 | 264 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB variant K164A, dioctanoyl phosphatidylinositol 3-phosphate (diC8-PtdIns3P) |
| MptpBvariant K164A | Mycobacterium tuberculosis | dioctanoyl phosphatidylinositol 4-phosphate (diC8-PtdIns4P) | 82.6 | 0.103 | 800 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB variant K164A, dioctanoyl phosphatidylinositol 4-phosphate (diC8-PtdIns4P) |
| MptpBvariant K164A | Mycobacterium tuberculosis | dioctanoyl phosphatidylinositol 5-phosphate (diC8-PtdIns5P) | 35.9 | 0.086 | 416 | pH 6, 37 °C | PMID 17584180 | Open record: MptpB variant K164A, dioctanoyl phosphatidylinositol 5-phosphate (diC8-PtdIns5P) |
| PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) | Homo sapiens | p-nitrophenyl phosphate | — | 1.5 | — | pH 7.5 | PMID 24892992 | Open record: PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1), p-nitrophenyl phosphate |
| PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain | Homo sapiens | p-nitrophenyl phosphateGST-tagged phosphatase (PP2C) domain; GST tag not removed | 0.0018 | 2.1 | 9 × 10⁻⁴ | pH 7.5 | PMID 24892992 | Open record: PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain, p-nitrophenyl phosphate |
| PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain | Homo sapiens | p-nitrophenyl phosphate | — | 1.5 | — | pH 7.5 | PMID 24892992 | Open record: PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain, p-nitrophenyl phosphate |
| PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain | Homo sapiens | p-nitrophenyl phosphate | 0.0022 | — | — | PMID 24892992 | Open record: PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain, p-nitrophenyl phosphate | |
| PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain | Homo sapiens | p-nitrophenyl phosphate | — | — | 2.94 × 10⁻⁵ | PMID 24892992 | Open record: PHLPP1 (PH domain leucine-rich repeat protein phosphatase 1) phosphatase domain, p-nitrophenyl phosphate | |
| PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain | Homo sapiens | HFPQF(pS)YSAS, serine-phosphorylated Akt hydrophobic-motif peptideGST-tagged phosphatase (PP2C) domain; GST tag not removed | 1.1 | 0.139 | 8 | pH 7.5 | PMID 24892992 | Open record: PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain, HFPQF(pS)YSAS, serine-phosphorylated Akt hydrophobic-motif peptide |
| PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain | Homo sapiens | HFPQF(pS)YSAS, serine-phosphorylated Akt hydrophobic-motif peptideresidue range not stated | 0.9 | 0.0405 | 22 | pH 7.5 | PMID 24892992 | Open record: PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain, HFPQF(pS)YSAS, serine-phosphorylated Akt hydrophobic-motif peptide |
| PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain | Homo sapiens | p-nitrophenyl phosphateGST-tagged phosphatase (PP2C) domain; GST tag not removed | 0.0018 | 1.8 | 0.001 | pH 7.5 | PMID 24892992 | Open record: PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain, p-nitrophenyl phosphate |
| PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain | Homo sapiens | p-nitrophenyl phosphateresidue range not stated | 0.37 | 1.3 | 0.285 | pH 7.5 | PMID 24892992 | Open record: PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain, p-nitrophenyl phosphate |
| PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain | Homo sapiens | p-nitrophenyl phosphate | — | — | 2.017 × 10⁻⁵ | PMID 24892992 | Open record: PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain, p-nitrophenyl phosphate | |
| PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain | Homo sapiens | RRA(pT)VA, threonine-phosphorylated peptide Arg-Arg-Ala-pThr-Val-AlaGST-tagged phosphatase (PP2C) domain; GST tag not removed | 0.15 | 0.064 | 2.3 | pH 7.5 | PMID 24892992 | Open record: PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain, RRA(pT)VA, threonine-phosphorylated peptide Arg-Arg-Ala-pThr-Val-Ala |
| PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain | Homo sapiens | RRA(pT)VA, threonine-phosphorylated peptide Arg-Arg-Ala-pThr-Val-Alaresidue range not stated | 1.1 | 0.063 | 18 | pH 7.5 | PMID 24892992 | Open record: PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) phosphatase domain, RRA(pT)VA, threonine-phosphorylated peptide Arg-Arg-Ala-pThr-Val-Ala |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | AAA(pT)VA phosphopeptide (phosphorylated residue in parentheses) | 1.052 | 0.206 | 5.2 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), AAA(pT)VA phosphopeptide (phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | AGPAL(pS)PVPPV phosphopeptide (Bcl2 Ser-87 site of the protein; phosphorylated residue in parentheses) | 1.307 | 0.357 | 3.3 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), AGPAL(pS)PVPPV phosphopeptide (Bcl2 Ser-87 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | ALSAG(pS)NEYLR phosphopeptide (ASK1 Ser-958 site of the protein; phosphorylated residue in parentheses) | 0.652 | 2.749 | 0.17 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), ALSAG(pS)NEYLR phosphopeptide (ASK1 Ser-958 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | ASQEP(pS)PAASA phosphopeptide (Drp1 Ser-548 site of the protein; phosphorylated residue in parentheses) | 0.615 | 0.114 | 5 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), ASQEP(pS)PAASA phosphopeptide (Drp1 Ser-548 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | DDA(pT)VA phosphopeptide (phosphorylated residue in parentheses) | 1.297 | 0.072 | 18 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), DDA(pT)VA phosphopeptide (phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | END(pT)INASL phosphopeptide (phosphorylated residue in parentheses) | 1.202 | 0.113 | 10.7 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), END(pT)INASL phosphopeptide (phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | ESEME(pT)PSAIN phosphopeptide (Bcl-XL Thr-47 site of the protein; phosphorylated residue in parentheses) | 0.385 | 0.05 | 8.3 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), ESEME(pT)PSAIN phosphopeptide (Bcl-XL Thr-47 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | HSAPP(pS)PEEKD phosphopeptide (ASK1 Ser-1033 site of the protein; phosphorylated residue in parentheses) | 0.857 | 0.026 | 32 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), HSAPP(pS)PEEKD phosphopeptide (ASK1 Ser-1033 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) | 1.332 | 0.023 | 57 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | NPCTE(pT)FTGTL phosphopeptide (ASK1 Thr-838 site of the protein; phosphorylated residue in parentheses) | 1.163 | 0.065 | 18 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), NPCTE(pT)FTGTL phosphopeptide (ASK1 Thr-838 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | PVART(pS)PLQTP phosphopeptide (Bcl2 Ser-70 site of the protein; phosphorylated residue in parentheses) | 0.642 | 0.098 | 6.7 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), PVART(pS)PLQTP phosphopeptide (Bcl2 Ser-70 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | RGRGS(pS)VGGGS phosphopeptide (ASK1 Ser-83 site of the protein; phosphorylated residue in parentheses) | 0.0255 | 0.656 | 0.033 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), RGRGS(pS)VGGGS phosphopeptide (ASK1 Ser-83 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | RRA(pS)VA phosphopeptide (phosphorylated residue in parentheses) | 0.928 | 1.354 | 0.67 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), RRA(pS)VA phosphopeptide (phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | RRA(pT)VA phosphopeptide (phosphorylated residue in parentheses) | 0.605 | 1.954 | 0.33 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), RRA(pT)VA phosphopeptide (phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | SQLHI(pT)PGTAY phosphopeptide (Bcl-XL Thr-115 site of the protein; phosphorylated residue in parentheses) | 0.395 | 0.48 | 0.83 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), SQLHI(pT)PGTAY phosphopeptide (Bcl-XL Thr-115 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | VARKL(pS)AREQR phosphopeptide (Drp1 Ser-637 site of the protein; phosphorylated residue in parentheses) | 0.862 | 0.409 | 2.2 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), VARKL(pS)AREQR phosphopeptide (Drp1 Ser-637 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)no WDXNWD peptide added; Table 2 | 1.027 | 0.028 | 37 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)effector peptide: 0 µM WT(52–74) peptide (no peptide) | 2.2 | 0.102 | 22 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)effector peptide: 40 µM WT(52–74) peptide; Table 3 series | 0.55 | 0.076 | 6.7 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)effector peptide: 100 µM A4(52–74) peptide; Table 3 series | 0.47 | 0.061 | 6.7 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; no WDXNWD peptide added; Fig. 2C experiment | — | 0.058 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; no WDXNWD peptide added; Fig. 2C experiment | — | 0.057 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; no WDXNWD peptide added; Fig. 3B experiment | — | 0.059 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; effector peptide: 5 µM WT(52–74) peptide | — | 0.114 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; effector peptide: 20 µM WT(52–74) peptide | — | 0.126 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; effector peptide: 30 µM WT(52–74) peptide | — | 0.074 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; ΔN25-PGAM5: lacking the first 25 residues | — | 0.096 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; effector peptide: 10 µM A4(52–74) peptide | — | 0.056 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses)10 nM enzyme; effector peptide: 50 µM A4(52–74) peptide | — | 0.046 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) | Homo sapiens | YLRSI(pS)LPVPV phosphopeptide (ASK1 Ser-966 site of the protein; phosphorylated residue in parentheses) | 0.483 | 0.237 | 2 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase), YLRSI(pS)LPVPV phosphopeptide (ASK1 Ser-966 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses)effector peptide: 0 µM WT(52–74) peptide (no peptide) | 0.0128 | 0.446 | 0.028 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses)effector peptide: 4 µM WT(52–74) peptide; Table 3 series | 0.18 | 0.818 | 0.223 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses)effector peptide: 15 µM WT(52–74) peptide; Table 3 series | 0.48 | 0.48 | 1 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses)effector peptide: 15 µM A4(52–74) peptide; Table 3 series | 0.0155 | 0.721 | 0.022 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses)500 nM enzyme; no WDXNWD peptide added; Fig. 3C experiment | — | 0.167 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses)500 nM enzyme; effector peptide: 0.5 µM WT(52–74) peptide | — | 0.423 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses)500 nM enzyme; effector peptide: 1 µM WT(52–74) peptide | — | 0.948 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses)500 nM enzyme; effector peptide: 2 µM WT(52–74) peptide | — | 0.777 | — | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, NFEDH(pS)APPSP phosphopeptide (ASK1 Ser-1029 site of the protein; phosphorylated residue in parentheses) |
| phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase)variant W58A/D59A/W62A/D63A | Homo sapiens | WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) | 0.0073 | 0.503 | 0.015 | pH 7.4 | PMID 25012655 | Open record: phosphoglycerate mutase 5 (PGAM5), long isoform PGAM5-L (Ser/Thr protein phosphatase) variant W58A/D59A/W62A/D63A, WHLAD(pS)PAVNG phosphopeptide (Bcl-XL Ser-62 site of the protein; phosphorylated residue in parentheses) |
| pyridoxal phosphatase (PLP phosphatase, hPLPP) | Homo sapiens | pyridoxal 5'-phosphate | 1.52 | 0.0025 | 608 | pH 7.4, 37 °C | PMID 14522954 | Open record: pyridoxal phosphatase (PLP phosphatase, hPLPP), pyridoxal 5'-phosphate |
| pyridoxal phosphatase (PLP phosphatase, hPLPP) | Homo sapiens | pyridoxamine 5'-phosphate | 0.45 | 0.0806 | 5.58 | pH 7.4, 37 °C | PMID 14522954 | Open record: pyridoxal phosphatase (PLP phosphatase, hPLPP), pyridoxamine 5'-phosphate |
| pyridoxal phosphatase (PLP phosphatase, hPLPP) | Homo sapiens | pyridoxine 5'-phosphate | 1.25 | 0.0434 | 27 | pH 7.4, 37 °C | PMID 14522954 | Open record: pyridoxal phosphatase (PLP phosphatase, hPLPP), pyridoxine 5'-phosphate |