EC 4.2.1.20: tryptophan synthase

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CatLog read 162 records for EC 4.2.1.20 from 10 papers, for 8 organisms. Names in these papers: tryptophan synthase alpha2.beta2 complex, tryptophan synthase α2β2 complex (β-replacement reaction), tryptophan synthase, tryptophan synthase alpha subunit (alphaTS) and 20 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 58 records for EC 4.2.1.20 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.2.1.20 in Browse.

Papers

Papers with records for EC 4.2.1.20
Paper	Organisms	Records
Enzymatic properties of mutant Escherichia coli tryptophan synthase alpha-subunits	Escherichia coli	88
Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium	Salmonella typhimurium	12
A novel tryptophan synthase beta-subunit from the hyperthermophile Thermotoga maritima. Quaternary structure, steady-state kinetics, and putative physiological role	Thermotoga maritima	10
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation	Pyrococcus furiosus	10
Severing of a hydrogen bond disrupts amino acid networks in the catalytically active state of the alpha subunit of tryptophan synthase	Escherichia coli	9
Directed Evolution Improves the Enzymatic Synthesis of L-5-Hydroxytryptophan by an Engineered Tryptophan Synthase	Escherichia coli	9
A naturally occurring standalone TrpB enzyme provides insights into allosteric communication within tryptophan synthase	Pelodictyon luteolum	8
The tryptophan synthase β-subunit paralogs TrpB1 and TrpB2 in Thermococcus kodakarensis are both involved in tryptophan biosynthesis and indole salvage	Thermococcus kodakarensis	6
Substitution of a Surface-Exposed Residue Involved in an Allosteric Network Enhances Tryptophan Synthase Function in Cells	Escherichia coli	6
TrpB2 enzymes are O-phospho-l-serine dependent tryptophan synthases	Arabidopsis thaliana, Sulfolobus solfataricus and 1 more	4

Records

Records for EC 4.2.1.20 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
atTrpB2o	Arabidopsis thaliana	O-phospho-L-serine	0.015	0.01	1.5	pH 7.5, 30 °C	PMID 25184516	Open record: atTrpB2o, O-phospho-L-serine
ssTrpB2a	Sulfolobus solfataricus	O-phospho-L-serine	0.015	0.014	1.1	pH 7.5, 60 °C	PMID 25184516	Open record: ssTrpB2a, O-phospho-L-serine
ssTrpB2i	Sulfolobus solfataricus	O-phospho-L-serine	0.3	0.015	20	pH 7.5, 60 °C	PMID 25184516	Open record: ssTrpB2i, O-phospho-L-serine
tmTrpB2o	Thermotoga maritima	O-phospho-L-serine	0.414	0.316	1.3	pH 7.5, 80 °C	PMID 25184516	Open record: tmTrpB2o, O-phospho-L-serine
TrpB1 (tryptophan synthase beta-subunit)	Thermococcus kodakarensis	indole(no TrpA)	1.04	0.0629	17	pH 7.5, 85 °C	PMID 24835339	Open record: TrpB1 (tryptophan synthase beta-subunit), indole
TrpB1 (tryptophan synthase beta-subunit)	Thermococcus kodakarensis	indolewith 5 µg TrpA (TrpAB complex)	3.46	0.035	99	pH 7.5, 85 °C	PMID 24835339	Open record: TrpB1 (tryptophan synthase beta-subunit), indole
TrpB1 (tryptophan synthase beta-subunit)	Thermococcus kodakarensis	L-serine	0.0018	12	1.5 × 10⁻⁴	pH 7.5, 85 °C	PMID 24835339	Open record: TrpB1 (tryptophan synthase beta-subunit), L-serine
TrpB2 (tryptophan synthase beta-subunit paralog)	Thermococcus kodakarensis	indole(no TrpA)	0.39	0.0081	48	pH 7.5, 85 °C	PMID 24835339	Open record: TrpB2 (tryptophan synthase beta-subunit paralog), indole
TrpB2 (tryptophan synthase beta-subunit paralog)	Thermococcus kodakarensis	indole	0.39	0.0076	51	pH 7.5, 85 °C	PMID 24835339	Open record: TrpB2 (tryptophan synthase beta-subunit paralog), indole
TrpB2 (tryptophan synthase beta-subunit paralog)	Thermococcus kodakarensis	L-serine	0.0056	1.58	0.00354	pH 7.5, 85 °C	PMID 24835339	Open record: TrpB2 (tryptophan synthase beta-subunit paralog), L-serine
tryptophan synthase	Escherichia coli	L-serine	0.38	0.33	1.15	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase, L-serine
tryptophan synthasevariant A67M	Escherichia coli	L-serine	0.12	0.21	0.57	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase variant A67M, L-serine
tryptophan synthasevariant D381G	Escherichia coli	L-serine	0.41	0.31	1.32	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase variant D381G, L-serine
tryptophan synthasevariant H313F	Escherichia coli	L-serine	0.32	0.29	1.1	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase variant H313F, L-serine
tryptophan synthasevariant L80H	Escherichia coli	L-serine	0.29	0.25	0.86	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase variant L80H, L-serine
tryptophan synthasevariant N64G/S352P	Escherichia coli	L-serine	0.16	0.23	0.69	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase variant N64G/S352P, L-serine
tryptophan synthasevariant P257R	Escherichia coli	L-serine	0.1	0.21	0.47	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase variant P257R, L-serine
tryptophan synthasevariant T319S	Escherichia coli	L-serine	0.32	0.3	1.06	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase variant T319S, L-serine
tryptophan synthasevariant V231A/K382G	Escherichia coli	L-serine	1.22	0.28	4.36	pH 8.5, 35 °C	PMID 34097254	Open record: tryptophan synthase variant V231A/K382G, L-serine
tryptophan synthase [tmTrpA·tmTrpB1]2 complex	Thermotoga maritima	indoleglycerol phosphate	4.14	0.016	260	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase [tmTrpA·tmTrpB1]2 complex, indoleglycerol phosphate
tryptophan synthase [tmTrpA·tmTrpB1]2 complex	Thermotoga maritima	L-serine	4.26	0.13	34	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase [tmTrpA·tmTrpB1]2 complex, L-serine
tryptophan synthase alpha subunit (alone, without beta2 subunit)	Escherichia coli	indole-3-glycerol phosphate	0.005	0.25	0.02	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha subunit (alone, without beta2 subunit), indole-3-glycerol phosphate
tryptophan synthase alpha subunit (alphaTS)	Escherichia coli	indole	0.095	0.926	0.103	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS), indole
tryptophan synthase alpha subunit (alphaTS)variant A71G	Escherichia coli	indole	0.02	1.84	0.0109	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS) variant A71G, indole
tryptophan synthase alpha subunit (alphaTS)variant T183V	Escherichia coli	indole	0.007	1.1	0.00636	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS) variant T183V, indole
tryptophan synthase alpha subunit (alphaTS)variant T183V/A158G	Escherichia coli	indole	0.007	0.804	0.00871	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS) variant T183V/A158G, indole
tryptophan synthase alpha subunit (alphaTS)variant T183V/A180G	Escherichia coli	indole	0.007	1.52	0.00461	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS) variant T183V/A180G, indole
tryptophan synthase alpha subunit (alphaTS)variant T183V/A185G	Escherichia coli	indole	0.007	0.782	0.00895	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS) variant T183V/A185G, indole
tryptophan synthase alpha subunit (alphaTS)variant T183V/A59G	Escherichia coli	indole	0.01	3.35	0.00299	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS) variant T183V/A59G, indole
tryptophan synthase alpha subunit (alphaTS)variant T183V/A67G	Escherichia coli	indole	0.011	0.842	0.0131	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS) variant T183V/A67G, indole
tryptophan synthase alpha subunit (alphaTS)variant T183V/A71G	Escherichia coli	indole	0.003	1.7	0.00176	pH 7.6, 25 °C	PMID 25377949	Open record: tryptophan synthase alpha subunit (alphaTS) variant T183V/A71G, indole
tryptophan synthase alpha subunit (αTS)	Escherichia coli	indole-3-glycerol phosphate	2.88 × 10⁻⁴	0.94	3.1 × 10⁻⁴	pH 7.5	PMID 34124159	Open record: tryptophan synthase alpha subunit (αTS), indole-3-glycerol phosphate
tryptophan synthase alpha subunit (αTS)variant A198W	Escherichia coli	indole-3-glycerol phosphate	3.81 × 10⁻⁴	1.31	2.9 × 10⁻⁴	pH 7.5	PMID 34124159	Open record: tryptophan synthase alpha subunit (αTS) variant A198W, indole-3-glycerol phosphate
tryptophan synthase alpha-subunit (tmTrpA) in the [tmTrpA·tmTrpB1]2 complex	Thermotoga maritima	indoleglycerol phosphate	5.6	0.19	29.5	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase alpha-subunit (tmTrpA) in the [tmTrpA·tmTrpB1]2 complex, indoleglycerol phosphate
tryptophan synthase alpha-subunit (tmTrpA), separated	Thermotoga maritima	indoleglycerol phosphate	0.174	1.62	0.11	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase alpha-subunit (tmTrpA), separated, indoleglycerol phosphate
tryptophan synthase alpha2.beta2 complex	Escherichia coli	indole	9.54	0.03	318	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex, indole
tryptophan synthase alpha2.beta2 complex	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.48	0.46	1.04	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complex	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6.64	0.041	162	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant A67V	Escherichia coli	indole	1.04	0.038	27	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant A67V, indole
tryptophan synthase alpha2.beta2 complexvariant A67V	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.047	0.51	0.09	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant A67V, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant A67V	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	0.7	0.15	4.7	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant A67V, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant C81R	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.233	0.23	1.01	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant C81R, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant C81R	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	3.83	0.028	136	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant C81R, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D112G	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.458	0.42	1.09	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D112G, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D112G	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	5.74	0.04	144	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D112G, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D112G (DG112)	Escherichia coli	indole-3-glycerol phosphate	—	—	1.09	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D112G (DG112), indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D112N	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.473	0.44	1.07	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D112N, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D112N	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	5.52	0.035	158	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D112N, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D112N (DN112)	Escherichia coli	indole-3-glycerol phosphate	—	—	1.07	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D112N (DN112), indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D46G	Escherichia coli	indole-3-glycerol phosphate	5.8	0.03	193	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D46G, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D46N	Escherichia coli	indole-3-glycerol phosphate	6.07	0.034	178	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D46N, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D56G	Escherichia coli	indole	0.19	0.024	7.9	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D56G, indole
tryptophan synthase alpha2.beta2 complexvariant D56G	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.054	0.22	0.24	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D56G, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant D56G	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	0.09	0.074	1.2	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant D56G, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant F114L	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.311	0.31	1.01	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant F114L, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant F114L	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6.18	0.064	97	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant F114L, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant F22S	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.048	0.27	0.18	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant F22S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant F22S	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	0.48	0.596	0.8	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant F22S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant G44S	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.408	0.37	1.1	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant G44S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant G44S	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6.09	0.037	165	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant G44S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant G51D	Escherichia coli	indole	4.29	0.018	238	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant G51D, indole
tryptophan synthase alpha2.beta2 complexvariant G51D	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.122	—	0.31	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant G51D, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant G51D	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	1.11	0.277	4	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant G51D, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant G51D (GD51)	Escherichia coli	indole-3-glycerol phosphate	—	0.39	—	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant G51D (GD51), indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant M101I	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.31	0.33	0.92	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant M101I, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant M101I	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	5.5	0.076	72	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant M101I, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant M101T	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.39	0.43	0.91	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant M101T, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant M101T	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	5.45	0.07	78	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant M101T, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant M101V	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.39	0.41	0.95	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant M101V, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant M101V	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	5.86	0.093	63	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant M101V, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant N104S	Escherichia coli	indole	2.7	0.032	84	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant N104S, indole
tryptophan synthase alpha2.beta2 complexvariant N104S	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.451	0.49	0.92	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant N104S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant N104S	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	4.93	0.065	76	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant N104S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P21S	Escherichia coli	indole	9.51	0.03	317.1	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P21S, indole
tryptophan synthase alpha2.beta2 complexvariant P21S	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.408	—	1.05	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P21S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P21S	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6.55	0.053	124	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P21S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P21S (PS21)	Escherichia coli	indole-3-glycerol phosphate	—	0.39	—	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P21S (PS21), indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P28L	Escherichia coli	indole	6.72	0.021	320	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P28L, indole
tryptophan synthase alpha2.beta2 complexvariant P28L	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.222	0.26	0.85	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P28L, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P28L	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	3.61	0.024	150	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P28L, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P28S	Escherichia coli	indole	9.47	0.034	278.6	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P28S, indole
tryptophan synthase alpha2.beta2 complexvariant P28S	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.419	—	0.95	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P28S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P28S	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6.12	0.039	157	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P28S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P53H	Escherichia coli	indole	0.49	0.024	20	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P53H, indole
tryptophan synthase alpha2.beta2 complexvariant P53H	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.039	0.39	0.1	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P53H, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P53H	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	1.1	0.119	9.3	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P53H, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P53T	Escherichia coli	indole	1.85	0.01	185	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P53T, indole
tryptophan synthase alpha2.beta2 complexvariant P53T	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.269	0.54	0.5	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P53T, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P53T	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	3.88	0.107	36.2	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P53T, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P62Q	Escherichia coli	indole	8.31	0.021	396	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P62Q, indole
tryptophan synthase alpha2.beta2 complexvariant P62Q	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.465	0.47	0.99	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P62Q, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P62Q	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	4.88	0.029	168	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P62Q, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P78L	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.422	0.29	1.11	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P78L, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P78L	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6	0.059	102	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P78L, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P78S	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.451	0.42	1.07	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P78S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P78S	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6.05	0.041	148	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P78S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant P98S	Escherichia coli	indole	9.04	0.026	350 calc.	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P98S, indole
tryptophan synthase alpha2.beta2 complexvariant P98S	Escherichia coli	indole-3-glycerol phosphate	0.476	0.48	0.99	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant P98S, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Q65R	Escherichia coli	indole	11.64	0.04	291	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Q65R, indole
tryptophan synthase alpha2.beta2 complexvariant Q65R	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.054	0.13	0.41	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Q65R, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Q65R	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	2.9	0.021	138	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Q65R, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant S33L	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.437	0.41	1.07	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant S33L, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant S33L	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	5.17	0.035	148	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant S33L, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant S6P	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.523	0.49	1.07	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant S6P, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant S6P	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6.2	0.031	200	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant S6P, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant T24M	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.58	0.98	1	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant T24M, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant T24M	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	6.49	0.049	132	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant T24M, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant T63K	Escherichia coli	indole	9.84	0.032	307	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant T63K, indole
tryptophan synthase alpha2.beta2 complexvariant T63K	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.136	0.15	0.91	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant T63K, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant T63K	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	2.71	0.059	46 calc.	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant T63K, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y102C	Escherichia coli	indole	0.76	0.04	19	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y102C, indole
tryptophan synthase alpha2.beta2 complexvariant Y102C	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.048	0.45	0.11	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y102C, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y102C	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	1.21	0.253	4.8	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y102C, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y102H	Escherichia coli	indole	7.63	0.032	238	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y102H, indole
tryptophan synthase alpha2.beta2 complexvariant Y102H	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.49	1.3	0.34	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y102H, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y102H	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	4.62	0.124	37.4	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y102H, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y115C	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.458	0.42	1.09	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y115C, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y115C	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	5.47	0.041	133	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y115C, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y115C (YC115)	Escherichia coli	indole-3-glycerol phosphate	—	—	1.09	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y115C (YC115), indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y4C	Escherichia coli	indole-3-glycerol phosphateno L-serine; InGP varied 0.05-0.2 mM	0.333	0.39	0.85	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y4C, indole-3-glycerol phosphate
tryptophan synthase alpha2.beta2 complexvariant Y4C	Escherichia coli	indole-3-glycerol phosphateInGP varied 0.05-0.2 mM with 40 mM L-serine	4.88	0.052	94	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase alpha2.beta2 complex variant Y4C, indole-3-glycerol phosphate
tryptophan synthase beta subunit (plTrpB)	Pelodictyon luteolum	indoleTrpB in isolation (no plTrpA)	—	0.039	8.97	pH 7.5, 30 °C	PMID 40100167	Open record: tryptophan synthase beta subunit (plTrpB), indole
tryptophan synthase beta subunit (plTrpB)	Pelodictyon luteolum	indole	—	0.065	14.3	pH 7.5, 30 °C	PMID 40100167	Open record: tryptophan synthase beta subunit (plTrpB), indole
tryptophan synthase beta subunit (plTrpB)	Pelodictyon luteolum	L-serineTrpB in isolation (no plTrpA)	0.35	21	0.017	pH 7.5, 30 °C	PMID 40100167	Open record: tryptophan synthase beta subunit (plTrpB), L-serine
tryptophan synthase beta subunit (plTrpB)	Pelodictyon luteolum	L-serine	0.93	5.6	0.166	pH 7.5, 30 °C	PMID 40100167	Open record: tryptophan synthase beta subunit (plTrpB), L-serine
tryptophan synthase beta subunit (plTrpB)variant E46A/E52D/T63S/S197T/A289G/M290N (plTrpB-con)	Pelodictyon luteolum	indoleTrpB in isolation (no plTrpA)	—	0.059	0.153	pH 7.5, 30 °C	PMID 40100167	Open record: tryptophan synthase beta subunit (plTrpB) variant E46A/E52D/T63S/S197T/A289G/M290N (plTrpB-con), indole
tryptophan synthase beta subunit (plTrpB)variant E46A/E52D/T63S/S197T/A289G/M290N (plTrpB-con)	Pelodictyon luteolum	indole	—	0.38	0.553	pH 7.5, 30 °C	PMID 40100167	Open record: tryptophan synthase beta subunit (plTrpB) variant E46A/E52D/T63S/S197T/A289G/M290N (plTrpB-con), indole
tryptophan synthase beta subunit (plTrpB)variant E46A/E52D/T63S/S197T/A289G/M290N (plTrpB-con)	Pelodictyon luteolum	L-serineTrpB in isolation (no plTrpA)	0.009	5.8	0.0016	pH 7.5, 30 °C	PMID 40100167	Open record: tryptophan synthase beta subunit (plTrpB) variant E46A/E52D/T63S/S197T/A289G/M290N (plTrpB-con), L-serine
tryptophan synthase beta subunit (plTrpB)variant E46A/E52D/T63S/S197T/A289G/M290N (plTrpB-con)	Pelodictyon luteolum	L-serine	0.21	0.013	16.2	pH 7.5, 30 °C	PMID 40100167	Open record: tryptophan synthase beta subunit (plTrpB) variant E46A/E52D/T63S/S197T/A289G/M290N (plTrpB-con), L-serine
tryptophan synthase beta subunit (βTS) in the α2β2 complex	Escherichia coli	indole	3.81	0.025	150	pH 7.5	PMID 34124159	Open record: tryptophan synthase beta subunit (βTS) in the α2β2 complex, indole
tryptophan synthase beta subunit (βTS) in the α2β2 complexvariant A198W αTS subunit	Escherichia coli	indole	3.08	0.016	190	pH 7.5	PMID 34124159	Open record: tryptophan synthase beta subunit (βTS) in the α2β2 complex variant A198W αTS subunit, indole
tryptophan synthase beta-subunit 1 (tmTrpB1) in the [tmTrpA·tmTrpB1]2 complex	Thermotoga maritima	indole	10	0.025	400	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase beta-subunit 1 (tmTrpB1) in the [tmTrpA·tmTrpB1]2 complex, indole
tryptophan synthase beta-subunit 1 (tmTrpB1) in the [tmTrpA·tmTrpB1]2 complex	Thermotoga maritima	L-serine	8	3.7	2.2	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase beta-subunit 1 (tmTrpB1) in the [tmTrpA·tmTrpB1]2 complex, L-serine
tryptophan synthase beta-subunit 1 (tmTrpB1), separated beta2 dimer	Thermotoga maritima	indole	4.2	0.04	100	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase beta-subunit 1 (tmTrpB1), separated beta2 dimer, indole
tryptophan synthase beta-subunit 1 (tmTrpB1), separated beta2 dimer	Thermotoga maritima	L-serine	3.8	110	0.034	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase beta-subunit 1 (tmTrpB1), separated beta2 dimer, L-serine
tryptophan synthase beta-subunit 2 (tmTrpB2), beta2 homodimer	Thermotoga maritima	indole	0.46	—	—	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase beta-subunit 2 (tmTrpB2), beta2 homodimer, indole
tryptophan synthase beta-subunit 2 (tmTrpB2), beta2 homodimer	Thermotoga maritima	L-serine	0.44	50.2	0.0087	pH 7.5, 80 °C	PMID 11756459	Open record: tryptophan synthase beta-subunit 2 (tmTrpB2), beta2 homodimer, L-serine
tryptophan synthase beta-subunit PfTrpB	Pyrococcus furiosus	indole	0.31	0.077	4	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase beta-subunit PfTrpB, indole
tryptophan synthase beta-subunit PfTrpB	Pyrococcus furiosus	L-serine	—	1.2	—	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase beta-subunit PfTrpB, L-serine
tryptophan synthase beta-subunit PfTrpBvariant E17G/I68V/T292S/F274S/T321A	Pyrococcus furiosus	indole	2.2	0.011	200	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase beta-subunit PfTrpB variant E17G/I68V/T292S/F274S/T321A, indole
tryptophan synthase beta-subunit PfTrpBvariant E17G/I68V/T292S/F274S/T321A	Pyrococcus furiosus	L-serine	—	1.2	—	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase beta-subunit PfTrpB variant E17G/I68V/T292S/F274S/T321A, L-serine
tryptophan synthase beta-subunit PfTrpBvariant P12L/E17G/I68V/T292S/F274S/T321A	Pyrococcus furiosus	indole	2.9	0.0087	330	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase beta-subunit PfTrpB variant P12L/E17G/I68V/T292S/F274S/T321A, indole
tryptophan synthase beta-subunit PfTrpBvariant P12L/E17G/I68V/T292S/F274S/T321A	Pyrococcus furiosus	L-serine	—	0.7	—	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase beta-subunit PfTrpB variant P12L/E17G/I68V/T292S/F274S/T321A, L-serine
tryptophan synthase beta-subunit PfTrpBvariant T292S	Pyrococcus furiosus	indole	1.1	0.014	78	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase beta-subunit PfTrpB variant T292S, indole
tryptophan synthase beta-subunit PfTrpBvariant T292S	Pyrococcus furiosus	L-serine	—	0.84	—	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase beta-subunit PfTrpB variant T292S, L-serine
tryptophan synthase beta2 subunit (alone, without alpha subunit)	Escherichia coli	indole	0.23	0.034	6.6	pH 7.8, 37 °C	PMID 1939081	Open record: tryptophan synthase beta2 subunit (alone, without alpha subunit), indole
tryptophan synthase PfTrpS (alpha2beta2 complex of PfTrpA and PfTrpB)	Pyrococcus furiosus	indole	1	0.02	50	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase PfTrpS (alpha2beta2 complex of PfTrpA and PfTrpB), indole
tryptophan synthase PfTrpS (alpha2beta2 complex of PfTrpA and PfTrpB)	Pyrococcus furiosus	L-serine	—	0.6	—	pH 8, 75 °C	PMID 26553994	Open record: tryptophan synthase PfTrpS (alpha2beta2 complex of PfTrpA and PfTrpB), L-serine
tryptophan synthase α2β2 complex	Escherichia coli	indole-3-glycerol phosphate	2.83	0.49	5.8	pH 7.5	PMID 34124159	Open record: tryptophan synthase α2β2 complex, indole-3-glycerol phosphate
tryptophan synthase α2β2 complexvariant A198W	Escherichia coli	indole-3-glycerol phosphate	4.14	0.42	9.9	pH 7.5	PMID 34124159	Open record: tryptophan synthase α2β2 complex variant A198W, indole-3-glycerol phosphate
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewithout monovalent cations (MVC-free)	0.24	1.6	0.16	pH 6.5, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 100 mM CsCl	6	9	0.67	pH 6.5, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 250 mM NaCl	1.9	4.78	0.41	pH 6.5, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 100 mM KCl	2.08	1.89	1.11	pH 6.5, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewithout monovalent cations (MVC-free)	0.91	1.6	0.57	pH 7.8, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 100 mM CsCl	8.7	5.6	1.59	pH 7.8, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 250 mM NaCl	2.8	0.52	4.9	pH 7.8, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 100 mM KCl	4.8	0.58	8.42	pH 7.8, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewithout monovalent cations (MVC-free)	1.37	2.7	0.52	pH 8.5, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 100 mM CsCl	6.15	1.9	3.31	pH 8.5, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 250 mM NaCl	1.9	0.14	13.66	pH 8.5, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine
tryptophan synthase α2β2 complex (β-replacement reaction)	Salmonella typhimurium	L-serinewith 100 mM KCl	4	0.27	14.76	pH 8.5, 20 °C	PMID 17927213	Open record: tryptophan synthase α2β2 complex (β-replacement reaction), L-serine