EC 5.3.1.24: phosphoribosylanthranilate isomerase

IsomerasesOpen in Browse

CatLog read 5 records for EC 5.3.1.24 from 3 papers, for 2 organisms. Names in these papers: indole-3-glycerol phosphate synthase (ecIGPS), IGPS:PRAI (bifunctional indoleglycerol phosphate synthase:phosphoribosyl anthranilate isomerase), phosphoribosyl anthranilate isomerase (monofunctional PRAI domain of IGPS:PRAI), phosphoribosylanthranilate isomerase (TrpF).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 35 records for EC 5.3.1.24 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 5.3.1.24 in Browse.

Papers

Papers with records for EC 5.3.1.24
Paper	Organisms	Records
Differences in the catalytic mechanisms of mesophilic and thermophilic indole-3-glycerol phosphate synthase enzymes at their adaptive temperatures	Escherichia coli	2
Indoleglycerol phosphate synthase-phosphoribosyl anthranilate isomerase: comparison of the bifunctional enzyme from Escherichia coli with engineered monofunctional domains	Escherichia coli	2
Two (betaalpha)(8)-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates	Thermotoga maritima	1

Records

Records for EC 5.3.1.24 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
IGPS:PRAI (bifunctional indoleglycerol phosphate synthase:phosphoribosyl anthranilate isomerase)	Escherichia coli	N-(5-phospho-beta-D-ribosyl)anthranilate	40	0.0049	8.2 × 10³	pH 7.5, 25 °C	PMID 7727400	Open record: IGPS:PRAI (bifunctional indoleglycerol phosphate synthase:phosphoribosyl anthranilate isomerase), N-(5-phospho-beta-D-ribosyl)anthranilate
indole-3-glycerol phosphate synthase (ecIGPS)	Escherichia coli	1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate	4.1	—	—	pH 7.5, 25 °C	PMID 22274606	Open record: indole-3-glycerol phosphate synthase (ecIGPS), 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate
indole-3-glycerol phosphate synthase (ecIGPS)	Escherichia coli	1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate	9.3	0.0016	5.7 × 10³	pH 7.5, 37 °C	PMID 22274606	Open record: indole-3-glycerol phosphate synthase (ecIGPS), 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate
phosphoribosyl anthranilate isomerase (monofunctional PRAI domain of IGPS:PRAI)variant V330A (PRAI[ML256-452])	Escherichia coli	N-(5-phospho-beta-D-ribosyl)anthranilate	32	0.0047	6.8 × 10³	pH 7.5, 25 °C	PMID 7727400	Open record: phosphoribosyl anthranilate isomerase (monofunctional PRAI domain of IGPS:PRAI) variant V330A (PRAI[ML256-452]), N-(5-phospho-beta-D-ribosyl)anthranilate
phosphoribosylanthranilate isomerase (TrpF)variant D126N	Thermotoga maritima	phosphoribosylanthranilate	—	0.0021	—	pH 7.5, 25 °C	PMID 12356303	Open record: phosphoribosylanthranilate isomerase (TrpF) variant D126N, phosphoribosylanthranilate