EC 6.1.1.1: tyrosine-tRNA ligase
LigasesOpen in Browse
CatLog read 41 records for EC 6.1.1.1 from 4 papers, for 3 organisms. Names in these papers: tyrosyl-tRNA synthetase (TyrRS), tyrosyl-tRNA synthetase (TyrRSapm).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 63 records for EC 6.1.1.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.1.1.1 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Biochemical Characterization of the Lysine Acetylation of Tyrosyl-tRNA Synthetase in Escherichia coli | Escherichia coli | 14 |
| Changing the amino acid specificity of yeast tyrosyl-tRNA synthetase by genetic engineering | Saccharomyces cerevisiae | 12 |
| Virus-encoded aminoacyl-tRNA synthetases: structural and functional characterization of mimivirus TyrRS and MetRS | Acanthamoeba polyphaga mimivirus | 11 |
| A mutant Escherichia coli tyrosyl-tRNA synthetase utilizes the unnatural amino acid azatyrosine more efficiently than tyrosine | Escherichia coli | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| tyrosyl-tRNA synthetase (TyrRS) | Escherichia coli | ATP | — | 0.43 | 33.02 | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS), ATP |
| tyrosyl-tRNA synthetase (TyrRS) | Escherichia coli | Escherichia coli tRNA(Tyr), in vitro T7 transcript | 1.32 | 3.7 × 10⁻⁴ | 3.51 × 10³ | pH 7.2, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS), Escherichia coli tRNA(Tyr), in vitro T7 transcript |
| tyrosyl-tRNA synthetase (TyrRS) | Escherichia coli | L-beta-(5-hydroxy-2-pyridyl)-alanine | 0.11 | 0.0177 | 6.2 calc. | pH 7.5, 30 °C | PMID 11006270 | Open record: tyrosyl-tRNA synthetase (TyrRS), L-beta-(5-hydroxy-2-pyridyl)-alanine |
| tyrosyl-tRNA synthetase (TyrRS) | Escherichia coli | L-tyrosine | 0.74 | 0.0033 | 220 calc. | pH 7.5, 30 °C | PMID 11006270 | Open record: tyrosyl-tRNA synthetase (TyrRS), L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS) | Escherichia coli | L-tyrosine | 14.2 | 0.00713 | 1.99 × 10³ | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS), L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant F130S | Escherichia coli | L-beta-(5-hydroxy-2-pyridyl)-alanine | 0.042 | 0.0376 | 1.1 calc. | pH 7.5, 30 °C | PMID 11006270 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant F130S, L-beta-(5-hydroxy-2-pyridyl)-alanine |
| tyrosyl-tRNA synthetase (TyrRS)variant F130S | Escherichia coli | L-tyrosine | 1.4 | 0.0661 | 21 calc. | pH 7.5, 30 °C | PMID 11006270 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant F130S, L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant K144AcK | Escherichia coli | ATP | — | 0.45 | 27.33 | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K144AcK, ATP |
| tyrosyl-tRNA synthetase (TyrRS)variant K144AcK | Escherichia coli | Escherichia coli tRNA(Tyr), in vitro T7 transcript | 1.17 | 4.2 × 10⁻⁴ | 2.78 × 10³ | pH 7.2, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K144AcK, Escherichia coli tRNA(Tyr), in vitro T7 transcript |
| tyrosyl-tRNA synthetase (TyrRS)variant K144AcK | Escherichia coli | L-tyrosine | 12.3 | 0.00782 | 1.57 × 10³ | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K144AcK, L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant K235AcK | Escherichia coli | ATP | — | 0.71 | 0.14 | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K235AcK, ATP |
| tyrosyl-tRNA synthetase (TyrRS)variant K235AcK | Escherichia coli | L-tyrosine | 0.1 | 0.00845 | 10 | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K235AcK, L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant K355AcK | Escherichia coli | ATP | — | 0.49 | 24.29 | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K355AcK, ATP |
| tyrosyl-tRNA synthetase (TyrRS)variant K355AcK | Escherichia coli | Escherichia coli tRNA(Tyr), in vitro T7 transcript | 1.09 | 4.8 × 10⁻⁴ | 2.27 × 10³ | pH 7.2, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K355AcK, Escherichia coli tRNA(Tyr), in vitro T7 transcript |
| tyrosyl-tRNA synthetase (TyrRS)variant K355AcK | Escherichia coli | L-tyrosine | 11.9 | 0.00669 | 1.78 × 10³ | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K355AcK, L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant K85AcK | Escherichia coli | ATP | — | 2.23 | 0.9 | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K85AcK, ATP |
| tyrosyl-tRNA synthetase (TyrRS)variant K85AcK | Escherichia coli | Escherichia coli tRNA(Tyr), in vitro T7 transcript | 0.15 | 4.5 × 10⁻⁴ | 330 | pH 7.2, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K85AcK, Escherichia coli tRNA(Tyr), in vitro T7 transcript |
| tyrosyl-tRNA synthetase (TyrRS)variant K85AcK | Escherichia coli | L-tyrosine | 2 | 0.00678 | 290 | pH 7.5, 37 °C | PMID 28741290 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant K85AcK, L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS) | Saccharomyces cerevisiae | 3-chloro-L-tyrosine | 0.13 | 2.04 | 0.065 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS), 3-chloro-L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS) | Saccharomyces cerevisiae | 3-fluoro-DL-tyrosine | 4.96 | 0.625 | 7.97 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS), 3-fluoro-DL-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS) | Saccharomyces cerevisiae | D-tyrosine | 1.2 | 0.459 | 2.62 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS), D-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS) | Saccharomyces cerevisiae | L-3,4-dihydroxyphenylalanine | 1.65 | 1.84 | 0.895 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS), L-3,4-dihydroxyphenylalanine |
| tyrosyl-tRNA synthetase (TyrRS) | Saccharomyces cerevisiae | L-tyrosine | 4.37 | 0.012 | 360 calc. | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS), L-tyrosine | |
| tyrosyl-tRNA synthetase (TyrRS) | Saccharomyces cerevisiae | L-tyrosine | 4.6 | 0.014 | 321 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS), L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant Y43G | Saccharomyces cerevisiae | 3-chloro-L-tyrosine | 1.46 | 2.43 | 0.602 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant Y43G, 3-chloro-L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant Y43G | Saccharomyces cerevisiae | 3-fluoro-DL-tyrosine | 0.62 | 1.3 | 0.475 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant Y43G, 3-fluoro-DL-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant Y43G | Saccharomyces cerevisiae | 3-iodo-L-tyrosine | 0.48 | 1.15 | 0.425 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant Y43G, 3-iodo-L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant Y43G | Saccharomyces cerevisiae | D-tyrosine | 0.37 | 14 | 0.027 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant Y43G, D-tyrosine |
| tyrosyl-tRNA synthetase (TyrRS)variant Y43G | Saccharomyces cerevisiae | L-3,4-dihydroxyphenylalanine | 0.67 | 0.56 | 1.02 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant Y43G, L-3,4-dihydroxyphenylalanine |
| tyrosyl-tRNA synthetase (TyrRS)variant Y43G | Saccharomyces cerevisiae | L-tyrosine | 0.95 | 1.19 | 0.804 | 30 °C | PMID 11530018 | Open record: tyrosyl-tRNA synthetase (TyrRS) variant Y43G, L-tyrosine |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | P. falciparum tRNATyr transcript | 0.0183 | 0.004 | 4.6 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), P. falciparum tRNATyr transcript |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr (native) | 0.126 | 5 × 10⁻⁴ | 250 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr (native) |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript | 0.142 | 0.0017 | 84 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript A36G | 0.0073 | 0.02 | 0.36 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript A36G |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript A36U | 0.0149 | 0.0154 | 0.968 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript A36U |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript G34A | 0.0075 | 0.0013 | 5.8 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript G34A |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript G34C | 0.0093 | 0.0014 | 6.6 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript G34C |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript G34U | 0.0083 | 0.0013 | 6.4 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript G34U |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript U35A | 0.0025 | 0.016 | 0.16 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript U35A |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript U35C | 0.01 | 0.0333 | 0.30 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript U35C |
| tyrosyl-tRNA synthetase (TyrRSapm) | Acanthamoeba polyphaga mimivirus | yeast tRNATyr transcript U35G | 0.0011 | 0.0093 | 0.12 calc. | pH 7.5, 30 °C | PMID 17855524 | Open record: tyrosyl-tRNA synthetase (TyrRSapm), yeast tRNATyr transcript U35G |