EC 6.3.3.4: (carboxyethyl)arginine beta-lactam-synthase

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CatLog read 22 records for EC 6.3.3.4 from 2 papers, for 1 organism. Names in these papers: β-lactam synthetase (βLS), β-lactam synthetase (β-LS).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 4 records for EC 6.3.3.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.3.3.4 in Browse.

Papers

Papers with records for EC 6.3.3.4
Paper	Organisms	Records
Engineering the synthetic potential of β-lactam synthetase and the importance of catalytic loop dynamics	—	18
A conserved tyrosyl-glutamyl catalytic dyad in evolutionarily linked enzymes: carbapenam synthetase and beta-lactam synthetase	Streptomyces clavuligerus	4

Records

Records for EC 6.3.3.4 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
β-lactam synthetase (β-LS)	Streptomyces clavuligerus	(2S,5S)-carboxymethylproline	0.026	4.9	0.0053 calc.	pH 8.3, 25 °C	PMID 19371088	Open record: β-lactam synthetase (β-LS), (2S,5S)-carboxymethylproline
β-lactam synthetase (β-LS)variant E382D	Streptomyces clavuligerus	N2-(2-carboxyethyl)-L-arginine	0.193	2.8	0.069	pH 8.8, 25 °C	PMID 19371088	Open record: β-lactam synthetase (β-LS) variant E382D, N2-(2-carboxyethyl)-L-arginine
β-lactam synthetase (β-LS)variant Y348A	Streptomyces clavuligerus	N2-(2-carboxyethyl)-L-arginine	0.0082	0.19	0.043	pH 8.8, 25 °C	PMID 19371088	Open record: β-lactam synthetase (β-LS) variant Y348A, N2-(2-carboxyethyl)-L-arginine
β-lactam synthetase (β-LS)variant Y348F	Streptomyces clavuligerus	N2-(2-carboxyethyl)-L-arginine	0.155	1.4	0.11	pH 8.8, 25 °C	PMID 19371088	Open record: β-lactam synthetase (β-LS) variant Y348F, N2-(2-carboxyethyl)-L-arginine
β-lactam synthetase (βLS)	—	N2-(2-carboxyethyl)-L-arginine	0.87	0.037	24 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS), N2-(2-carboxyethyl)-L-arginine
β-lactam synthetase (βLS)	—	N2-[(2R)-2-carboxybutyl]-L-arginine	0.004	—	—		PMID 23616913	Open record: β-lactam synthetase (βLS), N2-[(2R)-2-carboxybutyl]-L-arginine
β-lactam synthetase (βLS)	—	N2-[(2R)-2-carboxypropyl]-L-arginine	0.032	0.04	0.80 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS), N2-[(2R)-2-carboxypropyl]-L-arginine
β-lactam synthetase (βLS)	—	N2-[(2S)-2-carboxybutyl]-L-arginine	0.0023	0.06	0.038 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS), N2-[(2S)-2-carboxybutyl]-L-arginine
β-lactam synthetase (βLS)	—	N2-[(2S)-2-carboxypropyl]-L-arginine	0.023	0.06	0.38 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS), N2-[(2S)-2-carboxypropyl]-L-arginine
β-lactam synthetase (βLS)variant H447A	—	N2-(2-carboxyethyl)-L-arginine	0.016	0.9	0.018 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant H447A, N2-(2-carboxyethyl)-L-arginine
β-lactam synthetase (βLS)variant H447A	—	N2-[(2R)-2-carboxypropyl]-L-arginine	0.003	—	—		PMID 23616913	Open record: β-lactam synthetase (βLS) variant H447A, N2-[(2R)-2-carboxypropyl]-L-arginine
β-lactam synthetase (βLS)variant H447A	—	N2-[(2S)-2-carboxybutyl]-L-arginine	0.001	—	—		PMID 23616913	Open record: β-lactam synthetase (βLS) variant H447A, N2-[(2S)-2-carboxybutyl]-L-arginine
β-lactam synthetase (βLS)variant H447A	—	N2-[(2S)-2-carboxypropyl]-L-arginine	0.013	0.08	0.16 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant H447A, N2-[(2S)-2-carboxypropyl]-L-arginine
β-lactam synthetase (βLS)variant V446A	—	N2-(2-carboxyethyl)-L-arginine	0.28	0.36	0.78 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446A, N2-(2-carboxyethyl)-L-arginine
β-lactam synthetase (βLS)variant V446A	—	N2-[(2R)-2-carboxybutyl]-L-arginine	0.004	—	—		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446A, N2-[(2R)-2-carboxybutyl]-L-arginine
β-lactam synthetase (βLS)variant V446A	—	N2-[(2R)-2-carboxypropyl]-L-arginine	0.014	0.33	0.042 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446A, N2-[(2R)-2-carboxypropyl]-L-arginine
β-lactam synthetase (βLS)variant V446A	—	N2-[(2S)-2-carboxybutyl]-L-arginine	0.004	0.04	0.10 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446A, N2-[(2S)-2-carboxybutyl]-L-arginine
β-lactam synthetase (βLS)variant V446A	—	N2-[(2S)-2-carboxypropyl]-L-arginine	0.34	0.46	0.74 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446A, N2-[(2S)-2-carboxypropyl]-L-arginine
β-lactam synthetase (βLS)variant V446G	—	N2-(2-carboxyethyl)-L-arginine	0.13	0.61	0.21 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446G, N2-(2-carboxyethyl)-L-arginine
β-lactam synthetase (βLS)variant V446G	—	N2-[(2R)-2-carboxypropyl]-L-arginine	0.07	1.9	0.037 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446G, N2-[(2R)-2-carboxypropyl]-L-arginine
β-lactam synthetase (βLS)variant V446G	—	N2-[(2S)-2-carboxybutyl]-L-arginine	0.002	—	—		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446G, N2-[(2S)-2-carboxybutyl]-L-arginine
β-lactam synthetase (βLS)variant V446G	—	N2-[(2S)-2-carboxypropyl]-L-arginine	0.13	1.2	0.11 calc.		PMID 23616913	Open record: β-lactam synthetase (βLS) variant V446G, N2-[(2S)-2-carboxypropyl]-L-arginine